scholarly journals C-reactive Protein Predicts Systolic Blood Pressure and Pulse Pressure but not Diastolic Blood Pressure: the Cardiovascular Disease Risk Factors Two-Township Study

2013 ◽  
Vol 26 (5) ◽  
pp. 657-664 ◽  
Author(s):  
S.-Y. Chuang ◽  
P.-F. Hsu ◽  
H.-Y. Chang ◽  
C.-H. Bai ◽  
W.-T. Yeh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Pulse Pressure ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers

2017 ◽  
Vol 32 (2) ◽  
pp. 154-164 ◽  
Author(s):  
Christopher J. Morris ◽  
Taylor E. Purvis ◽  
Joseph Mistretta ◽  
Kun Hu ◽  
Frank A. J. L. Scheer
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
C Reactive Protein ◽  
Shift Workers ◽  
Circadian Misalignment ◽  
Reactive Protein ◽  
Hs Crp

Shift work is a risk factor for inflammation, hypertension, and cardiovascular disease. This increased risk cannot be fully explained by classical risk factors. Shift workers’ behavioral and environmental cycles are typically misaligned relative to their endogenous circadian system. However, there is little information on the impact of acute circadian misalignment on cardiovascular disease risk in shift workers, independent of differences in work stress, food quality, and other factors that are likely to differ between night and day shifts. Thus, our objectives were to determine the independent effect of circadian misalignment on 24-h high-sensitivity C-reactive protein (hs-CRP; a marker of systemic inflammation) and blood pressure levels—cardiovascular disease risk factors—in chronic shift workers. Chronic shift workers undertook two 3-day laboratory protocols that simulated night work, comprising 12-hour inverted behavioral and environmental cycles (circadian misalignment) or simulated day work (circadian alignment), using a randomized, crossover design. Circadian misalignment increased 24-h hs-CRP by 11% ( p < 0.0001). Circadian misalignment increased 24-h systolic blood pressure (SBP) and diastolic blood pressure (DBP) by 1.4 mmHg and 0.8 mmHg, respectively (both p ≤ 0.038). The misalignment-mediated increase in 24-h SBP was primarily explained by an increase in SBP during the wake period (+1.7 mmHg; p = 0.017), whereas the misalignment-mediated increase in 24-h DBP was primarily explained by an increase in DBP during the sleep opportunity (+1.8 mmHg; p = 0.005). Circadian misalignment per se increases hs-CRP and blood pressure in shift workers. This may help explain the increased inflammation, hypertension, and cardiovascular disease risk in shift workers.

scholarly journals The Effects of Job Instability and Financial Strain on C-Reactive Protein in a Sample of Mexican Immigrants

2016 ◽  
Vol 26 (1) ◽  
pp. 37 ◽  
Author(s):  
Patrick R. Steffen ◽  
Jill Walker ◽  
Richard Meredith ◽  
Chris Anderson
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Job Stress ◽  
Mexican Immigrants ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Financial Strain ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Job Instability

<p><strong>Objective:</strong> Mexican immigrants have lower cardiovascular disease risk than US citizens, but risk increases with level of acculturation. Our study investigated whether job stress and financial strain would be related to inflammation (C-reactive protein), lipids, and blood pressure, and if they would play a role in the acculturation process in Mexican immigrants.  </p><p><strong>Method:</strong> A sample of 310 Mexican immigrants living in the United States were studied on measures of job stress, financial strain, acculturation, and cardiovascular disease risk factors (C-reactive protein, lipids, and blood pressure). </p><p><strong>Results:</strong> Job instability, financial strain, and acculturation, were related to inflammation, but psychological demands and decision latitude were not related. Lipids and clinic blood pressure were not related to the variables of interest. Body mass index was related to both increased acculturation and inflammation, and when controlling for BMI, acculturation was no longer a significant predictor of inflammation. Job instability and financial strain remained significant predictors of inflammation after controlling for BMI, gender, and age. Job instability and financial strain were not related to acculturation, suggesting that these factors are significant stressors for both newly arrived and more established immigrants.</p><p><strong>Conclusions:</strong> Job instability and financial strain predict increased inflammation in Mexican immigrants but they do not play a role in the relationship between acculturation and C-reactive protein. The effects of acculturation on inflammation in this study were mediated by BMI. <em>Ethn Dis.</em> 2016;26(1):37-44; doi: 10.18865/ed.26.1.37</p>

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