scholarly journals RBANS Validity Measures and the TOMM in Veterans Undergoing Seizure Monitoring

2020 ◽  
Author(s):  
Laurence Binder ◽  
Martin C Salinsky ◽  
Daniel Storzbach ◽  
Sandy K Tadrous-Furnanz
Keyword(s):  
Positive Likelihood Ratio ◽  
Epileptic Seizures ◽  
Cutoff Score ◽  
Performance Validity ◽  
Test Of Memory Malingering ◽  
Psychogenic Nonepileptic Seizures ◽  
Neuropsychological Status ◽  
Embedded Measures ◽  
Validity Measures ◽  
Nonepileptic Seizures

Abstract Objective To assess the validity of embedded measures of performance validity, the effort index (EI) and effort scale (ES) of the repeatable battery for the assessment of neuropsychological status (RBANS), in Veterans with seizures; to compare the frequency of failure on the test of memory malingering (TOMM) in patients with epileptic versus psychogenic nonepileptic seizures (PNES). Methods Seizure diagnosis was established for 309 participants in epilepsy monitoring units using conventional diagnostic criteria who completed both the TOMM and RBANS. The criterion for performance invalidity was failure on any trial of the TOMM. We examined multiple EI and ES cutoffs to establish optimal sensitivity and specificity. Results An RBANS EI cutoff score of greater than three was optimal with specificity of .98, sensitivity of.19, and positive Likelihood Ratio of 10 but was not useful when below this cutoff. Confidence intervals indicate the need for confirmation of a failed EI with another performance validity test (PVT). No ES cutoff had sufficient specificity for clinical use. Invalid TOMM performance but not invalid RBANS performance was significantly more common in persons with PNES than in persons with epileptic seizures. Conclusions In Veterans undergoing seizure monitoring, the RBANS EI was useful as a screen when positive that requires confirmation with another PVT. The RBANS ES was not useful. Invalid performance on the TOMM was more common in persons with PNES than in persons with epileptic seizures.

scholarly journals Neuropsychological aspects of psychogenic nonepileptic seizures

2007 ◽  
Vol 13 (4 suppl 1) ◽  
pp. 24-27
Author(s):  
Mirna Wetters Portuguez ◽  
Danielle Irigoyen da Costa ◽  
Sabine Possa Marroni ◽  
Vanessa Pagliarini ◽  
Karin Vieira
Keyword(s):  
Sexual Abuse ◽  
Physical Abuse ◽  
Multidisciplinary Team ◽  
Emotional Abuse ◽  
Epileptic Seizures ◽  
Mental Processes ◽  
Psychogenic Nonepileptic Seizures ◽  
Therapeutic Procedures ◽  
Nonepileptic Seizures ◽  
The Brain

Psychogenic nonepileptic seizures (PNES) may be defined as paroxysmal changes in behavior that are similar to epileptic seizures but are not associated with quantifiable alterations in the electrical activity of the brain. At the Epilepsy Surgery Program (ESP) of the São Lucas Hospital at PUCRS (HSL-PUCRS), we studied 52 individuals (37 females and 15 males) with a diagnosis of PNES, associated (57%) or not (23%) with refractory epileptic seizures. We found emotional abuse (100%), physical abuse (80%), emotional neglect (80%), physical negligence (70%) and sexual abuse (30%), mood (40%) and anxiety disorders (50%), as the main psychological components in such population. Although the medical and psychosocial impact of PNES can be estimated as significant, the absence of specialized services for its treatment is striking. Multiple diagnostic and therapeutic procedures and the participation of a specialized multidisciplinary team – where neuropsychology functions as a link between the mental processes/psychopathologies and the brain – are required to ensure proper management of such cases.

Mechanisms of Possible Neurocognitive Dysfunction

2017 ◽  
Author(s):  
Daniel L. Drane ◽  
Dona E. C. Locke
Keyword(s):  
Neuropsychological Testing ◽  
Psychological Theory ◽  
Future Research ◽  
Performance Validity ◽  
Post Traumatic Stress ◽  
Neurocognitive Dysfunction ◽  
Psychogenic Nonepileptic Seizures ◽  
Nonepileptic Seizures ◽  
Performance Validity Measures ◽  
Validity Tests

This chapter covers what is known about the possible mechanisms of neurocognitive dysfunction in patients with psychogenic nonepileptic seizures (PNES). It begins with a review of all research examining possible cognitive deficits in this population. Cognitive research in PNES is often obscured by noise created by a host of comorbid conditions (e.g., depression, post-traumatic stress disorder, chronic pain) and associated issues (e.g., effects of medications and psychological processes that can compromise attention or broader cognition). More recent studies employing performance validity tests raise the possibility that studies finding broad cognitive problems in PNES may be highlighting a more transient phenomenon secondary to these comorbid or secondary factors. Such dysfunction would likely improve with successful management of PNES symptomatology, yet the effects of even transient variability likely compromises daily function until these issues are resolved. Future research must combine the use of neuropsychological testing, performance validity measures, psychological theory, neuroimaging analysis, and a thorough understanding of brain–behavior relationships to address whether there is a focal neuropathological syndrome associated with PNES.

scholarly journals Spectrum of Nonepileptic Paroxysmal Events in Children from Southern India

2019 ◽  
Vol 10 (04) ◽  
pp. 608-612
Author(s):  
Vykuntaraju K Gowda ◽  
Raghavendraswami Amoghimath ◽  
Naveen Benakappa ◽  
Sanjay K Shivappa
Keyword(s):  
Children And Adolescents ◽  
Age Of Onset ◽  
Age Groups ◽  
Epileptic Seizures ◽  
Breath Holding ◽  
Home Video ◽  
Psychogenic Nonepileptic Seizures ◽  
Wrong Diagnosis ◽  
Nonepileptic Seizures ◽  
Eeg Recordings

Abstract Background Nonepileptic paroxysmal events (NEPEs) present with episodes similar to epileptic seizures but without abnormal electrical discharge on electroencephalogram (EEG). NEPEs are commonly misdiagnosed as epilepsy. Epilepsy is diagnosed on the basis of a detailed history and examination. Emphasis during history to rule out the possibility of NEPE is important. The wrong diagnosis of epilepsy can lead to physical, psychological, and financial harm to the child and the family. Hence, this study was planned. Objective The objective of the study is to evaluate clinical profile, frequency, and spectrum of NEPE in children. Materials and Methods This is a prospective observational study. Patients with NEPE between January 2014 and August 2016 aged < 18 years were enrolled. NEPEs were diagnosed on the basis of history, home video, and EEG recordings. Patients were divided into different categories according to age, specific type of disorder, and system responsible. Patients were followed for their NEPE frequency and outcome. Results A total of 3,660 children presented with paroxysmal events; of them 8% were diagnosed with NEPE. Patients diagnosed with NEPE were classified into three age groups on the basis of their age of onset of symptom; of the total 285 patients, there were 2 neonates (0.7%), 160 infants (56%), and 123 children and adolescents (43.1%). Fifty-eight percent patients were boys. The most common diagnoses were breath-holding spells 113 (39%), followed by syncope 38 (13.3%) and psychogenic nonepileptic seizures 37 (12.9%). About 9 and 5% of patients had concomitant epilepsy and developmental delay, respectively. Conclusions NEPEs account for 8% of paroxysmal events. Most common NEPEs were breath-holding spells among infants and syncope and “psychogenic nonepileptic seizures” in children and adolescents.

Validity testing in veterans with epileptic seizures and psychogenic nonepileptic seizures

2020 ◽  
Vol 111 ◽  
pp. 107246 ◽  
Author(s):  
Martin Salinsky ◽  
Laurence Binder ◽  
Daniel Storzbach ◽  
Karen Parko ◽  
Paul Rutecki ◽  
...  
Keyword(s):  
Epileptic Seizures ◽  
Validity Testing ◽  
Psychogenic Nonepileptic Seizures ◽  
Nonepileptic Seizures

Practical and Diagnostic Challenges for the Neuropsychologist

2017 ◽  
Author(s):  
Kim Willment ◽  
David Loring
Keyword(s):  
Decision Making ◽  
Psychological Distress ◽  
Neuropsychological Evaluation ◽  
Performance Validity ◽  
Cognitive Profiles ◽  
Therapeutic Goals ◽  
Psychogenic Nonepileptic Seizures ◽  
Clinical Environments ◽  
Nonepileptic Seizures ◽  
Neuropsychological Findings

The objective of this chapter is to outline practical and diagnostic challenges in the clinical neuropsychological evaluation of patients with psychogenic nonepileptic seizures (PNES) and to aid neuropsychologists in developing a consistent decision-making protocol. Challenges outlined include responding to performance validity test (PVT) failures, testing in different clinical environments, medications effects, acute psychological distress, and length of evaluations. Diagnostic challenges related to the neuropsychological evaluation in PNES, including the lack of specificity of cognitive profiles and psychopathological heterogeneity, are discussed. The final focus of the chapter is therapeutic goals of the neuropsychological evaluation, particularly the integration of the neuropsychological findings during the delivery of the PNES diagnosis and promoting cognitive self-efficacy.

Prolonged Exposure Therapy for Comorbid Psychogenic Nonepileptic Seizures and Posttraumatic Stress Disorder

2017 ◽  
Vol 17 (1) ◽  
pp. 3-20 ◽  
Author(s):  
Lorna Myers ◽  
Laurie Zandberg
Keyword(s):  
Posttraumatic Stress ◽  
Prolonged Exposure ◽  
Epileptic Seizures ◽  
Psychological Trauma ◽  
Psychogenic Nonepileptic Seizures ◽  
Full Remission ◽  
Stress Symptoms ◽  
Prolonged Exposure Therapy ◽  
History Of ◽  
Nonepileptic Seizures

Psychogenic nonepileptic seizures (PNES) superficially resemble epileptic seizures but are not associated with epileptic discharges in the brain. Instead, these episodes, which tend to occur with alterations in consciousness and body movements, are thought to be the result of mechanisms of conversion and dissociation. Psychological trauma and PTSD are very prevalent among patients with PNES. PNES can be conceived of as an extreme avoidance mechanism that serves the function of modulating distress and, in some cases, eliminating the precipitant stressor. Avoidance is also an essential component of PTSD. In patients who carry a dual diagnosis of PNES and PTSD, it is sensible that an empirically validated treatment for PTSD such as prolonged exposure (PE) therapy which targets avoidance by promoting exposure might be a useful approach to treat these patients. In this report, we present the case of a 52-year-old male with a 7-year history of PNES. His seizures, which were characterized by intense body shaking and loud guttural outbursts, were occurring up to 15 times per day. Because of these symptoms, he lost his employment and was ostracized by his family. Upon completion of a course of intensive outpatient PE, he achieved full remission of all psychogenic symptoms. Except for three brief seizures, he has maintained his health for 2 years. This constitutes the first detailed report of PE therapy used to effectively treat comorbid PNES and posttraumatic stress symptoms.

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