scholarly journals P087 LONG TERM SURGICAL RESULTS AND QUALITY OF LIFE AFTER LAPAROSCOPIC INGUINAL HERNIA REPAIR (TAPP): A PROSPECTIVE, CASE CONTROL STUDY COMPARING STANDARD HEAVYWEIGHT AND SELFGRIPPING (PROGRIP) MESH

2021 ◽  
Vol 108 (Supplement_8) ◽  
Author(s):  
Sara Capoccia Giovannini ◽  
Marco Frascio ◽  
Lisa Rossi ◽  
Cesare Stabilini

Abstract Aim Aim of this study is to compare long term results of efficacy, recurrence and quality of life in patients submitted to TAPP for inguinal hernia repair with standard Heavyweight or Selfgripping mesh. Material and Methods A prospective case control study was conducted at single third referral center. The study included adult patients submitted to TAPP, of both sex, with primary and recurrent, unilateral and bilateral inguinal hernia. Patients received non-fixated standard heavyweight meshes (HW) or PROGRIP self gripping mesh (PG), their data were entered in EuraHS platform and the EuraHS Quality of life (QOL) questionnaire was administered before and 1 year after surgery. Primary outcome of the study is to compare long term QOL before and after surgery in HW vs PG group. Secondary outcome is perioperative morbidity and 12 months recurrence assessed with PINQ questionnaire. Results Between 2016 and 2020, 100 patients of both sexes (10 female) were enrolled, 50 in HW group and 50 in PG group. The two groups were comparable preoperatively. After 12 months no cases of CPIP were observed and there wasn’t differences in QOL reported by patients, although in both groups there was an improvement of pain, movement limitations and esthetical discomfort after surgery. None recurrence and overall only 4 cases of complications (1 hematoma and 1 seroma for each group) were registered. Conclusions Selfgripping Mesh for laparoscopic hernia repair has produced results equal to standard of care meshes in term of recurrence rate, early morbidity and postoperative quality of life of patients.

2011 ◽  
Vol 25 (10) ◽  
pp. 3353-3356 ◽  
Author(s):  
Shiu-Dong Chung ◽  
Chao-Yuan Huang ◽  
Shih-Chieh Chueh ◽  
Yao-Chou Tsai ◽  
Hong-Jeng Yu

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Ida Kathrine Gravensteen ◽  
Linda Bjørk Helgadottir ◽  
Eva-Marie Jacobsen ◽  
Per Morten Sandset ◽  
Øivind Ekeberg

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e032583
Author(s):  
Helen Marshall ◽  
Mark McMillan ◽  
Bing Wang ◽  
Robert Booy ◽  
Hossein Afzali ◽  
...  

IntroductionInvasive meningococcal disease (IMD) primarily causes disease in young children and adolescents and can cause long-term disability. Many countries are considering implementation of meningococcal B and/or meningococcal ACWY vaccines to control meningococcal disease. Estimating the cost-effectiveness of meningococcal vaccine programme is hampered due to a lack of good quality costing and burden of disease data. This study aims to address this evidence gap by assessing the clinical, physical, neurocognitive, economic and societal impact of IMD on adolescents and young adults.Methods and analysisA case–control study of 64 participants with confirmed IMD (15–24 years 11 months at time of disease) and 64 control participants (17–34 years 11 months) will be conducted in Australia from 2016 to 2020. All participants will undergo a neurocognitive assessment, full medical examination, pure tone audiometry assessment and complete quality of life and behavioural questionnaires. Meningococcal cases will be assessed 2–10 years posthospitalisation and a subset of cases will be interviewed to explore in depth their experiences of IMD and its impact on their life. Primary outcome measures include general intellectual functioning from the Wechsler Adult Intelligence Scale and overall quality of life from the Health Utilities Index. Secondary outcome measures include academic achievement, executive functioning, behaviour, hearing, psychological and physical functioning. Outcome measures will be compared between cases and controls using independent t-tests or ORs, or if any significant confounders are identified, adjusted analyses (analysis of covariance or adjusted ORs) will be conducted. Thematic analysis will be used to analyse transcribed interviews and a costing model will be used to project lifetime costs.Ethics and disseminationThe Adolescent MENingococcal Disease (AMEND) study has been approved by the Human Research Ethics Committee of the Women’s and Children’s Health Network (HREC/14/WCHN/024). The results will be disseminated via peer-reviewed publications, conference presentations, study participants, and meningococcal and meningitis foundations.Trial registration numberNCT03798574.


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