scholarly journals Apo-10′-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo

2007 ◽  
Vol 28 (7) ◽  
pp. 1567-1574 ◽  
Author(s):  
Fuzhi Lian ◽  
Donald E. Smith ◽  
Hansgeorg Ernst ◽  
Robert M. Russell ◽  
Xiang-Dong Wang
2020 ◽  
Vol 19 ◽  
pp. 153303381990111
Author(s):  
Xi Yu ◽  
Hong Zheng ◽  
Rongfei Sun ◽  
Xuejiao Qian ◽  
Ping Jiang ◽  
...  

Lung cancer is the most common cancer type with increasingly high incidence. MicroRNAs provide the potential biomarkers for lung cancer treatment. Thus, we aimed to investigate the function of microRNA-425-5p in lung cancer development and the underlying mechanisms. MicroRNA-425-5p overexpression inhibited A549 lung cancer cell proliferation in vitro and in vivo. On the other hand, microRNA-425-5p inhibition increased A549 proliferation. Mechanistically, the underlying mechanism by which microRNA-425-5p inhibits lung cancer cell growth was mediated through its ability in targeting and downregulating the TFIIB-related factor 2. Our results for the first time identified microRNA-425-5p as a tumor suppressor in lung cancer. Thus, microRNA-425-5p may serve as a potential therapeutic target for lung cancer.


2017 ◽  
Vol 7 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Tiancong Wu ◽  
Ji Geng ◽  
Wenjie Guo ◽  
Jing Gao ◽  
Xixu Zhu

Oncotarget ◽  
2016 ◽  
Vol 8 (19) ◽  
pp. 30817-30829 ◽  
Author(s):  
Yuanyuan Zeng ◽  
Jianjie Zhu ◽  
Dan Shen ◽  
Hualong Qin ◽  
Zhe Lei ◽  
...  

2013 ◽  
Vol 32 (5) ◽  
pp. 1137-1149 ◽  
Author(s):  
ARASH MINAI-TEHRANI ◽  
SEUNG-HEE CHANG ◽  
SEUNG BUM PARK ◽  
MYUNG-HAING CHO

Lung Cancer ◽  
2012 ◽  
Vol 77 ◽  
pp. S35
Author(s):  
Kyung-A. Lee ◽  
Kyeong-Nam Yu ◽  
Seung-Hee Chang ◽  
Myung-Haing Cho

2021 ◽  
Author(s):  
Hui‐qiong Zhang ◽  
Xiao‐fang Xie ◽  
Gang‐min Li ◽  
Jun‐ren Chen ◽  
Meng‐ting Li ◽  
...  

2019 ◽  
Vol 25 ◽  
pp. 836-846 ◽  
Author(s):  
Xiaohu Zhou ◽  
Shanshan Liu ◽  
Xuemei Lin ◽  
Liping Xu ◽  
Xiaoming Mao ◽  
...  

2017 ◽  
Vol 37 (3) ◽  
pp. 1793-1803 ◽  
Author(s):  
Xin Liu ◽  
Xin Wu ◽  
Yuefan Ma ◽  
Wenzhang Zhang ◽  
Liang Hu ◽  
...  

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