scholarly journals Temporal Dynamics of Anti-Type 1 Interferon Autoantibodies in COVID-19 Patients

2021 ◽  
Author(s):  
Elana R Shaw ◽  
Lindsey B Rosen ◽  
Aristine Cheng ◽  
Kerry Dobbs ◽  
Ottavia M Delmonte ◽  
...  
Keyword(s):  
Temporal Dynamics ◽  
Viral Disease ◽  
Healthy Individuals ◽  
Neutralization Activity ◽  
Type 1 Interferon

Abstract Binding levels and neutralization activity of anti-type 1 interferon (T1IFN) autoantibodies peaked during acute COVID-19 and markedly decreased thereafter. Most patients maintained some ability to neutralize T1IFN into convalescence despite lower levels of binding IgG. Identifying these autoantibodies in healthy individuals before they develop critical viral disease may be challenging.

scholarly journals Antibody Inhibition of a Viral Type 1 Interferon Decoy Receptor Cures a Viral Disease by Restoring Interferon Signaling in the Liver

2012 ◽  
Vol 8 (1) ◽  
pp. e1002475 ◽  
Author(s):  
Ren-Huan Xu ◽  
Daniel Rubio ◽  
Felicia Roscoe ◽  
Tracy E. Krouse ◽  
Mary Ellen Truckenmiller ◽  
...  
Keyword(s):  
Viral Disease ◽  
Interferon Signaling ◽  
Type 1 Interferon ◽  
Decoy Receptor ◽  
Viral Type ◽  
Antibody Inhibition

Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D

2021 ◽  
Author(s):  
Yan Wang ◽  
Xiaolei Zhang ◽  
Yujie Guo ◽  
Xiao Li ◽  
Guanyi Guo ◽  
...  
Keyword(s):  
Type 1 Interferon

Type 1 interferon signature as a diagnostic marker of dermatomyositis

2017 ◽  
Vol 381 ◽  
pp. 1082
Author(s):  
A. Uruha ◽  
Y. Allenbach ◽  
J.L. Charuel ◽  
L. Musset ◽  
A. Aussy ◽  
...  
Keyword(s):  
Diagnostic Marker ◽  
Interferon Signature ◽  
Type 1 Interferon

scholarly journals Increased UBE2L6 regulated by type 1 interferon as potential marker in TB

2021 ◽  
Author(s):  
Jiao Gao ◽  
Chonghui Li ◽  
Wenjing Li ◽  
Haotian Chen ◽  
Yurong Fu ◽  
...  
Keyword(s):  
Type 1 Interferon ◽  
Potential Marker

scholarly journals Azithromycin and glucosamine may amplify the type 1 interferon response to RNA viruses in a complementary fashion

2020 ◽  
Vol 228 ◽  
pp. 83-85
Author(s):  
James J. DiNicolantonio ◽  
Jorge Barroso-Aranda ◽  
Mark F. McCarty
Keyword(s):  
Rna Viruses ◽  
Interferon Response ◽  
Type 1 Interferon
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