Rapid Solubility Test for Detection of Hemoglobin S

1971 ◽  
Vol 17 (11) ◽  
pp. 1081-1082 ◽  
Author(s):  
Jean E Matusik ◽  
James B Powell ◽  
David M Gregory
Keyword(s):  
Phosphate Buffer ◽  
Screening Test ◽  
Rapid Screening ◽  
Hemoglobin S ◽  
Solubility Test ◽  
Negative Results ◽  
Rapid Screening Test

Abstract We have devised a rapid screening test for use in detecting sickling hemoglobins. This test depends on the insolubility of sickling hemoglobins in 2.24 molar phosphate buffer. Sickling hemoglobins form a turbid suspension in this test, in which positive and negative results, respectively, appear very much like those for the "Sickledex" test.

Clinical Evaluation of a Rapid Screening Test for Sickle Cell Trait (S[unknown]) and Sickle Cell Anemia (SS)

1974 ◽  
Vol 20 (7) ◽  
pp. 761-764 ◽  
Author(s):  
Allan L Louderback ◽  
Young Youhne ◽  
Anthony Fontana ◽  
Martin Natland
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Screening Test ◽  
Sickle Cell Trait ◽  
Sodium Dithionite ◽  
Test System ◽  
Rapid Screening ◽  
Single Test ◽  
Solubility Test ◽  
Rapid Screening Test

Abstract The need for a rapid screening procedure that differentiates both sickle-cell trait (S[unknown]) and sickle-cell anemia (SS) in a single test system has led to the development of a new 10-min screening test. The "Sickle-I.D." system is based on a modification of the sodium dithionite hemoglobin solubility test. It is composed of three reagents and requires 0.1 ml of whole blood. Two independent blind clinical comparisons of this new procedure with hemoglobin electrophoresis (4328 samples) revealed an accuracy of 99.8% in identification and differentiation of sicklecell trait and sickle-cell anemia. Together with confirmation of positives by hemoglobin electrophoresis, this new procedure provides rapid and accurate screening for sickle-cell trait (S[unknown]) and sickle-cell anemia (SS).

Rapid screening test for porphyrinuria

1970 ◽  
Vol 102 (2) ◽  
pp. 237-237
Author(s):  
R. M. McDonald
Keyword(s):  
Screening Test ◽  
Rapid Screening ◽  
Rapid Screening Test

A Rapid Screening Test for Detection of Poisons in Blood

Nature ◽  
1962 ◽  
Vol 193 (4822) ◽  
pp. 1298-1298 ◽  
Author(s):  
H. V. STREET
Keyword(s):  
Screening Test ◽  
Rapid Screening ◽  
Rapid Screening Test

Erythrocyte adenosine transport a rapid screening test for cardiovascular drugs

1993 ◽  
Vol 30 (3) ◽  
pp. 163-167 ◽  
Author(s):  
Pollen K.F. Yeung ◽  
Susan J. Mosher ◽  
Rongshi Li ◽  
Patrick S. Farmer ◽  
Gerald A. Klassen ◽  
...  
Keyword(s):  
Screening Test ◽  
Cardiovascular Drugs ◽  
Rapid Screening ◽  
Rapid Screening Test ◽  
Adenosine Transport

Rapid screening test evaluation for microalbuminuria in diabetes mellitus

1998 ◽  
Vol 35 (4) ◽  
pp. 199-202 ◽  
Author(s):  
I. Fernández Fernández ◽  
J. M. Páez Pinto ◽  
T. Hermosín Bono ◽  
P. Vázquez Garijo ◽  
M. A. Ortiz Camuñez ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Screening Test ◽  
Rapid Screening ◽  
Test Evaluation ◽  
Rapid Screening Test

Rapid Screening Test for the Evaluation of Quaternary Ammonium Compounds by Triphenyltetrazolium Chloride Reduction by Microorganisms

1970 ◽  
Vol 53 (6) ◽  
pp. 1224-1228
Author(s):  
Raymond J Sitkiewicz
Keyword(s):  
Quaternary Ammonium ◽  
Screening Test ◽  
Rapid Test ◽  
Test System ◽  
Quaternary Ammonium Compounds ◽  
Rapid Screening ◽  
Ammonium Compound ◽  
Triphenyltetrazolium Chloride ◽  
Rapid Screening Test ◽  
Ammonium Compounds

Abstract A rapid screening test has been developed to determine killing dilutions of quaternary ammonium compounds. Two factors, Letheen broth as a quaternary ammonium compound neutralizer and triphenyltetrazolium chloride as a microbial growth indicator, resulted in a rapid test system for the evaluation of quaternary ammonium compounds. This rapid test system takes from 4 to 8 hr to complete as opposed to the 24 to 48 hr for other tests. A new germicide can be bacteriologically screened in one day.

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