Determination of aluminum in biological samples by atomic absorption spectrophotometry with a graphite furnace.

1978 ◽  
Vol 24 (9) ◽  
pp. 1485-1490 ◽  
Author(s):  
J E Gorsky ◽  
A A Dietz
Keyword(s):  
Atomic Absorption ◽  
Biological Fluids ◽  
Graphite Furnace ◽  
Atomic Absorption Spectrophotometry ◽  
Graphite Tube ◽  
Sample Handling ◽  
Absorption Spectrophotometry ◽  
Precision And Accuracy ◽  
The Brain

Abstract Aluminum, generally considered non-essential and non-toxic, may accumulate in toxic amounts in the brain in cases of chronic renal failure. We describe a procedure for its analysis in biological fluids by atomic absorption spectrophotometry with a graphite furnace. No sample preparation is required and the procedure is sensitive at the appropriate concentrations. A sample of serum or urine is pipetted into the interior of the graphite tube, where it is sequentially dried, charred, and atomized. Precautions for sample handling are discussed and instrument settings are defined. Precision and accuracy of the method are evaluated, as are the effects of salts, protein content of serum, and specific gravity of urine. Serum of 23 persons who were not consuming aluminum-containing antacids contained 28 +/- 9 (SD) microgram of Al per liter (1.02 +/- 0.33 mumol/liter).

scholarly journals Improved electrothermal determination of aluminum in serum by atomic absorption spectroscopy.

1980 ◽  
Vol 26 (2) ◽  
pp. 258-260 ◽  
Author(s):  
F R Alderman ◽  
H J Gitelman
Keyword(s):  
Detection Limit ◽  
Atomic Absorption ◽  
Absorption Spectroscopy ◽  
Atomic Absorption Spectroscopy ◽  
Graphite Furnace ◽  
Atomic Absorption Spectrophotometry ◽  
Graphite Tube ◽  
Improved Method ◽  
Absorption Spectrophotometry

Abstract We describe an improved method for determination of aluminum in serum by atomic absorption spectrophotometry with a graphite furnace. Interferences have been controlled and total combustion of the samples achieved by the use of new diluent in a molybdenum-treated graphite tube. The detection limit of this method is 2 microgram/L.

scholarly journals Improved electrothermal determination of aluminum in serum by atomic absorption spectroscopy.

1980 ◽  
Vol 26 (2) ◽  
pp. 258-260 ◽  
Author(s):  
F R Alderman ◽  
H J Gitelman
Keyword(s):  
Detection Limit ◽  
Atomic Absorption ◽  
Absorption Spectroscopy ◽  
Atomic Absorption Spectroscopy ◽  
Graphite Furnace ◽  
Atomic Absorption Spectrophotometry ◽  
Graphite Tube ◽  
Improved Method ◽  
Absorption Spectrophotometry

Abstract We describe an improved method for determination of aluminum in serum by atomic absorption spectrophotometry with a graphite furnace. Interferences have been controlled and total combustion of the samples achieved by the use of new diluent in a molybdenum-treated graphite tube. The detection limit of this method is 2 microgram/L.

Determination of Mercury in Food Products and Biological Fluids by Aeration and Flameless Atomic Absorption Spectrophotometry

1971 ◽  
Vol 54 (1) ◽  
pp. 206-210 ◽  
Author(s):  
Virginia A Thorpe
Keyword(s):  
Atomic Absorption ◽  
Biological Fluids ◽  
Food Products ◽  
Atomic Absorption Spectrophotometry ◽  
Good Precision ◽  
Flameless Atomic Absorption ◽  
Absorption Spectrophotometry ◽  
Wet Digestion ◽  
Mercury In Fish

Abstract This paper describes a simple, rapid modification of a method developed at the Fisheries Research Board of Canada for determining mercury in fish and other food products. Wet digestion and flameless techniques of atomic absorption spectrophotometry are used. Replicate analyses on different days showed good precision and samples spiked with known amounts of mercury showed adequate recovery.

A sensitive high-temperature electrothermal atomic absorption analysis for Rb+ in erythrocytes and plasma of normal and hypertensive persons.

1985 ◽  
Vol 31 (2) ◽  
pp. 274-276 ◽  
Author(s):  
K F Hallis ◽  
N A Boon ◽  
C M Perkins ◽  
J K Aronson ◽  
D G Grahame-Smith
Keyword(s):  
Atomic Absorption ◽  
Healthy Subjects ◽  
Graphite Furnace ◽  
Atomic Absorption Spectrophotometry ◽  
Absorption Analysis ◽  
Healthy Individuals ◽  
Absorption Spectrophotometry ◽  
Graphite Furnace Atomic Absorption ◽  
The Matrix

Abstract This method for determination of Rb+ in human plasma and erythrocytes by graphite-furnace atomic absorption spectrophotometry has a sensitivity of 29 nmol/L for plasma, 12 nmol/L for erythrocytes. The detection limit is 24 nmol/L for plasma, 4.8 nmol/L for erythrocytes. This assay is approximately 30-fold more sensitive than previously reported techniques involving atomic absorption spectrophotometry, enabling use of smaller samples. The rubidium signal is linear with concentration up to 1.2 mumol/L, and addition of other cations to the matrix produces only minor alterations in the Rb+ signal. We measured plasma and erythrocytic Rb+ concentrations in healthy subjects and in patients with untreated essential hypertension. In both, our values are similar to those previously reported for healthy individuals.

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