scholarly journals Multisystem inflammatory syndrome in adults (MIS-A) associated with SARS-CoV-2 infection with delayed-onset myocarditis: case report

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Miles Shen ◽  
Aidan Milner ◽  
Carlo Foppiano Palacios ◽  
Tariq Ahmad
Keyword(s):  
Cardiovascular Complications ◽  
Clinical Syndrome ◽  
Resonance Imaging ◽  
Non Invasive ◽  
Respiratory Involvement ◽  
Case Summary ◽  
Organ Systems ◽  
Magnetic Resonance Imaging Mri ◽  
Inflammatory Syndrome ◽  
Supportive Management

Abstract Background During the Coronavirus disease 2019 (COVID-19) pandemic, reports have emerged of a multisystem inflammatory syndrome in adults (MIS-A). Multisystem inflammatory syndrome in adults can affect various organ systems, including cardiovascular, gastrointestinal, and neurologic systems without significant respiratory involvement. Case summary A previously healthy 43-year-old man presented with fevers and abdominal pain then rapidly deteriorated into cardiogenic shock. His constellation of symptoms along with elevated inflammatory markers in the setting of a recent SARS-CoV-2 infection was consistent with the diagnosis of MIS-A. He also had a comprehensive infectious workup that was unremarkable, ruling out other potential infectious aetiologies for his presentation. He subsequently improved through supportive measures and after administration of intravenous immunoglobulin (IVIG). He later demonstrated recovery of cardiac function and cardiac magnetic resonance imaging (MRI) showed signs consistent with myocarditis. Discussion As the COVID-19 pandemic continues to be an ongoing issue, it is important to recognize MIS-A, a rare and potentially deadly clinical syndrome that can lead to profound cardiovascular complications. Non-invasive imaging modalities such as cardiac MRI can play a role in the identification of myocarditis. In addition to supportive management, adjunctive therapies such as IVIG may be efficacious in MIS-A and should be further investigated.

scholarly journals Non-invasive diagnostics in fossils - Magnetic Resonance Imaging of pathological belemnites

2005 ◽  
Vol 2 (2) ◽  
pp. 133-140 ◽  
Author(s):  
D. Mietchen ◽  
H. Keupp ◽  
B. Manz ◽  
F. Volke
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Soft Tissue ◽  
Clinical Diagnostics ◽  
Resonance Imaging ◽  
Non Invasive ◽  
Physiological Processes ◽  
Magnetic Resonance Imaging Mri ◽  
Invasive Diagnostics

Abstract. For more than a decade, Magnetic Resonance Imaging (MRI) has been routinely employed in clinical diagnostics because it allows non-invasive studies of anatomical structures and physiological processes in vivo and to differentiate between healthy and pathological states, particularly of soft tissue. Here, we demonstrate that MRI can likewise be applied to fossilized biological samples and help in elucidating paleopathological and paleoecological questions: Five anomalous guards of Jurassic and Cretaceous belemnites are presented along with putative paleopathological diagnoses directly derived from 3D MR images with microscopic resolution. Syn vivo deformities of both the mineralized internal rostrum and the surrounding former soft tissue can be traced back in part to traumatic events of predator-prey-interactions, and partly to parasitism. Besides, evidence is presented that the frequently observed anomalous apical collar might be indicative of an inflammatory disease. These findings highlight the potential of Magnetic Resonance techniques for further paleontological applications.

scholarly journals Left ventricular pseudoaneurysm: an inadvertent consequence of COVID-19—a case report

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
Stephen Brennan ◽  
Saadah Sulong ◽  
Matthew Barrett
Keyword(s):  
Multimodal Imaging ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Left Ventricular ◽  
Medical Complications ◽  
Mechanical Complication ◽  
Resonance Imaging ◽  
Left Ventricular Pseudoaneurysm ◽  
Non Invasive ◽  
Case Summary

Abstract Background Left ventricular pseudoaneurysm (LVP) is an uncommon but serious mechanical complication of acute myocardial infarction (AMI). The immediate medical complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are well recognized, but its indirect effect on patients and healthcare systems is potentially less perceivable. Case summary In this report, a 72-year-old man who was anxious about attending hospital during the SARS-CoV-2 pandemic was eventually found to have a total right coronary artery occlusion after a delayed emergency department presentation. He ultimately developed severe symptomatic heart failure and cardiac magnetic resonance imaging (CMR) revealed that a large LVP with concomitant severe ischaemic mitral regurgitation had evolved from his infarct. The patient was successfully discharged home after the surgical replacement of his mitral valve and repair of his LVP. Discussion This case highlights a salient downstream effect of Coronavirus disease 2019 (COVID-19): the delay in presentation, diagnosis, and management of common treatable conditions such as AMI. It also underscores the importance of non-invasive multimodal imaging on the timely identification of the mechanical complications of AMI. In particular, CMR can play a crucial role in the characterization and management of LVP.

Human Birth Imaging Using MRI: Prospective cohort study (Preprint)

2021 ◽  
Author(s):  
Olivier Ami ◽  
Jean Christophe Maran ◽  
Dominique Musset ◽  
Claude Dubray ◽  
Gérard Mage ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Neurological Impairment ◽  
Invasive Technique ◽  
Resonance Imaging ◽  
Effective Utilization ◽  
Medical Risk ◽  
Non Invasive ◽  
Bony Pelvis ◽  
Magnetic Resonance Imaging Mri ◽  
Human Birth

UNSTRUCTURED Childbirth is a physiologic process with significant medical risk, as neurological impairment due to the birthing process can occur at any time. Improvements in risk assessment and anticipatory interventions are constantly needed; however, the birthing process is difficult to assess using simple imaging technology since the maternal bony pelvis and fetal skeleton interfere with visualizing the soft tissues. Magnetic resonance imaging (MRI) is a non-invasive technique with no ionizing radiation that can monitor the biomechanics of the birthing process. Effective utilization of this modality, however, requires teamwork and implementation of the appropriate safeguards to achieve appropriate safety levels. This article describes a clinically effective and safe method to perform real-time MRI during the birthing process. We report the experience of our team as part of the IMAGINAITRE research protocol (France), which aimed better understand of the biomechanics of childbirth. 

Neuroimaging Techniques and Their Application in the Spinal Cord

2016 ◽  
Vol 2 (4) ◽  
pp. 211-214
Author(s):  
Yong Hu
Keyword(s):  
Spinal Cord ◽  
Neural Function ◽  
Functional Information ◽  
Resonance Imaging ◽  
Spinal Disorders ◽  
Human Spinal Cord ◽  
Non Invasive ◽  
Conventional Mri ◽  
Magnetic Resonance Imaging Mri ◽  
Neuroimaging Techniques

Non-invasive neuroimaging plays a crucial role in the assessment of the human spinal cord, but it is quite challenging. Magnetic resonance imaging (MRI) is an important modality to obtain both high-resolution anatomical and functional information concerning the spinal cord. Besides conventional MRI, advanced MRI techniques could provide novel information about the microstructure and neural function of the spinal cord, thereby enhancing the understanding of spinal cord neurology and pathology of various spinal disorders.

scholarly journals Non-invasive imaging of plant roots in different soils using magnetic resonance imaging (MRI)

Plant Methods ◽  
2017 ◽  
Vol 13 (1) ◽  
Author(s):  
Daniel Pflugfelder ◽  
Ralf Metzner ◽  
Dagmar van Dusschoten ◽  
Rüdiger Reichel ◽  
Siegfried Jahnke ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Plant Roots ◽  
Resonance Imaging ◽  
Non Invasive ◽  
Magnetic Resonance Imaging Mri ◽  
Different Soils

Successful pregnancy after natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis

2016 ◽  
Vol 23 (3) ◽  
pp. 483-486 ◽  
Author(s):  
Kalliopi Pitarokoili ◽  
Kerstin Hellwig ◽  
Carsten Lukas ◽  
Ralf Gold
Keyword(s):  
Multiple Sclerosis ◽  
Progressive Multifocal Leukoencephalopathy ◽  
Clinical Presentation ◽  
Dimethyl Fumarate ◽  
Resonance Imaging ◽  
Successful Pregnancy ◽  
Uncomplicated Pregnancy ◽  
Pregnancy And Delivery ◽  
Magnetic Resonance Imaging Mri ◽  
Inflammatory Syndrome

We report the case of a post-progressive multifocal leukoencephalopathy (PML), multiple sclerosis (MS) patient with an uncomplicated pregnancy and delivery. A 28-year-old woman on natalizumab (total of 49 infusions) was diagnosed with PML due to typical magnetic resonance imaging (MRI) and clinical presentation. John Cunningham virus (JCV) was detected in the cerebrospinal fluid (CSF) during the immune reconstitution inflammatory syndrome (IRIS). Nine months after PML onset, JCV negativity in the CSF was observed. MS was stabilised with dimethyl fumarate (DMF), and 18 months later, a desired pregnancy was reported, resulting in the birth of a healthy boy. Our report gives new hope regarding family planning for post-PML patients.

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