Pediatric Resident Education in Pediatric Cardiology – A Needs Assessment

Background: Although congenital heart disease is the most common human birth defect, the scope and breadth of pediatric cardiology is far more diverse. Additionally, there continues to be rapid advancements in the field with educators becoming increasingly sub-specialized. As such, determining the topics general pediatric residents are taught must be selected based on numerous factors including resident career goals, core topics for board exams, and educator preferences. This study aimed to determine if the educational needs of general pediatric residents are met while on a pediatric cardiology rotation. Methods: All PL-2 and PL-3 residents in the Children’s National Hospital pediatrics residency program who had completed a required cardiology rotation as well as all pediatric cardiology fellows and pediatric cardiology attendings were asked to complete a survey. Participation in the study was voluntary. Respondents were asked to answer questions related to the perceived effectiveness and applicability of the currently administered cardiology curriculum, specifically inquiring about methods of teaching, the level taught, and the utility of topics selected. Results: Twenty-four (31%) of the 77 eligible residents completed the survey. Fourteen (82%) of the eligible attendings and nine (75%) of the cardiology fellows completed the survey. Seventeen unique topics in pediatric cardiology were ranked. The highest rated topics based on both perceived needs and wants included congenital heart disease, murmurs, cardiac physiology, ECG interpretation, and syncope/dizziness. Participants reported the highest satisfaction for whiteboard and bedside teaching. Conclusions: Overall, general pediatrics residents were satisfied with the current educational design of the inpatient cardiology rotation. These data provide a framework, both in teaching modalities and core concepts, for continued development and reassessment of inpatient pediatric cardiology rotations to optimally prepare pediatric residents with a strong foundation in pediatric cardiology.

Etiquettes of Cultural Parables in Sangam Literature

Sangam literature are used to clearly understand the development of civilized society and literary richness or off luence. The literature named after the parable can be said to be sangam literature. We call a parable, an analogy that composes one object to another. We could find this kind of analogy in writings of noble laureates naturally this parable is nurtured with human birth. Through the beautiful usages of parable in sangam literary pieces one can see the growth of culture. The parable is the supreme tool for cultivating culture and the key used to open the springs of emotions to the pinnacle of languages. Through this research article we come to know how parable works as the highly appreciatable tool of language and how it can beanty one’s writing.

The analysis of the socio-economic situation of Scandinavian countries using the macroeconomic generalizing indicator of development.

The socio-economic development of the country is the goal of every state. An important element in achieving this goal is the availability and application of a macroeconomic generalizing indicator that reveals the purpose of public policy. The main aim of the study is to identify the socio-economic characteristics of the organization of life in the countries of Scandinavia, using the macroeconomic generalizing indicator RAZ (the name of the indicator is based on the first part of the Russian word “razvitie” translated as “development”), proposed by the authors. The authors consider this indicator as suitable for cross-country comparisons of the quality of life and an objective estimation of development of the society from the point of view of focusing on the maximum disclosure of person's abilities and personal development. The research was based on the methods of analysis, synthesis, comparison, generalization and modeling, as well as on the case-study method. The use of these methods made it possible to identify the characteristics of the socio-economic organization of life and characteristics defining quality of life (human birth, education and medical care) in their composition, and also the indicators corresponding to them characterizing qualitative changes — levels of human birth rate, education and medical care. The generalized estimation of the specified characteristics defining quality of life, it is offered to make by means of a macroeconomic generalizing indicator. For its calculation a set of the quantity indicators defining quality of life (population in the country, number of the persons trained in an education system and number of healthy people) is generated. The authors make an assessment of the macroeconomic generalizing indicator and the set of the quantity indicators defining quality of life (the population in the country, the number of healthy people and the number of people studying in the education system).The study has developed an approach to calculating defining quality of life indicators using the System of National Accounts according to the data of the European Bureau of Statistical Research and the official websites of the national statistical services of the countries of Scandinavia and Switzerland as a country that has indicators close to the leading values of the countries of Scandinavia. These estimates can be used for comparative analysis purposes. The study compiled a rating of countries according to the macroeconomic generalizing indicator. According to calculations, Norway occupies a leading position. The lowest rank is observed in Sweden. There are changes in the quality of life in society, and this complex phenomenon requires an objective assessment. Generalizing indicator of the development provides such an assessment. The indicator allows us to evaluate the set of characteristics that determine the quality of life, which is not yet taken into account in cross-country comparisons, and to compare them. It has been established that the lack of development of the conceptual apparatus and the unavailability of important statistical information complicate the principle of compiling the indicator and lead to an inaccurate calculation of the macroeconomic generalizing indicator at this study stage. Nevertheless, it was found out that the calculation could be made in relation to the following levels: humanity (world), country, region or city. Further research is planned to study substantiation of the conceptual device of formation of RAZ as indicator for cross-country comparisons of quality of life and an objective estimation of development of the society, as well as for using it as a modelling element of social and economic systems. Besides, it is necessary to develop additional characteristics that take into account the influence of a person’s life expectancy on the quality of his life, as well as in clarifying the conceptual apparatus for forming a macroeconomic generalizing indicator RAZ for building a rational organization of people's place of residence. This approach creates new theoretical and methodological foundations for scientific knowledge of the socio-economic development of the countries and allows us to analyze the quality of life as a base which moves development of the countries in different historical periods and to see the development of the world in the future in a different way.

Neuroblast migration along cellular substrates in the developing porcine brain

In the past decade it has become evident that neuroblasts continue to supply the human cortex with interneurons via unique migratory streams shortly following birth. Due to the size of the human brain, these newborn neurons must migrate long distances through complex cellular landscapes to reach their final locations. This process is poorly understood, largely due to technical difficulties in acquiring and studying neurotypical postmortem human samples along with diverging developmental features of well-studied mouse models. We reasoned that migratory streams of neuroblasts utilize cellular substrates, such as blood vessels, to guide their trek from the subventricular zone to distant cortical targets. Here we evaluate the association between young interneuronal migratory streams and their preferred cellular substrates in gyrencephalic piglets during the developmental equivalent of human birth, infancy, and toddlerhood.

Dynamic finite-element simulations reveal early origin of complex human birth pattern

Human infants are born neurologically immature, but whether this originates from conflicting selection pressures between bipedal locomotion and encephalization as suggested by the obstetrical dilemma remains controversial. Australopithecines are ideal for investigating this trade-off as they have a bipedally adapted pelvis, yet relatively small brains. Our finite-element birth simulations based on different pelvic reconstructions and a range of fetal head sizes indicate that australopithecines already possessed a human-like rotational birth pattern. Since only newborn head sizes smaller than those predicted for non-human primates leave adequate space for soft tissue between the bony pelvis and fetal skull, our data imply that australopithecines had secondarily altricial newborns and likely evolved cooperative breeding to care for their helpless infants. These prerequisites for advanced cognitive development therefore seem to have been corollary to skeletal adaptations to bipedal locomotion that preceded the appearance of the genus Homo and the increase in encephalization.

Principles of Theological touch in Vallarars work - An analysis

The article is being carried out on the theocratic principle given by vallalar. In these, the morals of the philanthropists are explained to the people of today's society. It is not mankind that a man is born, lived, and then dies. It is only in human birth that there is a possibility of seeing and attaining God. That is why the philanthropist instructs us on some ethics. Love and compassion should be felt in all living beings. This article reveals that those who act with in their heart can truly reach God, who completely eliminates caste, religion and race differences, and who, when they suffer from hunger, who relieves them of suffering and who takes pity without killing any of them, can reach God by heart.

Organoids to model the endometrium: implantation and beyond

Despite advances in assisted reproductive techniques in the four decades since the first human birth after in vitro fertilisation, 1-2 % of couples experience recurrent implantation failure, and some will never achieve a successful pregnancy even in the absence of a confirmed dysfunction. Furthermore, 1-2 % of couples who do conceive, either naturally or with assistance, will experience recurrent early loss of karyotypically normal pregnancies. In both cases, embryo-endometrial interaction is a clear candidate for exploration. The impossibility of studying implantation processes within the human body has necessitated the use of animal models and cell culture approaches. Recent advances in 3-dimensional modelling techniques, namely the advent of organoids, present an exciting opportunity to elucidate the unanswerable within human reproduction. In this review, we will explore the ontogeny of implantation modelling and propose a roadmap to application and discovery.