scholarly journals Recurrent ST-Elevation Myocardial Infarction: Case Report of A Rare Complication of Caseous Mitral Annular Calcification

2021 ◽  
Author(s):  
Nikhil Singh ◽  
Atman P Shah ◽  
Gianluca Torregrossa ◽  
John E Blair
Keyword(s):  
Myocardial Infarction ◽  
Mitral Valve ◽  
Recurrent Events ◽  
Early Recognition ◽  
Rare Complication ◽  
Mitral Annular Calcification ◽  
Imaging Evaluation ◽  
Increased Risk ◽  
Stage Renal Disease ◽  
Annular Calcification

Abstract Background Caseous mitral annular calcification is an under-diagnosed division of calcific mitral valve disease that has recently been reported to have increased propensity for embolic disease. Early recognition of this entity as a cause of embolic disease can lead to prevention of occlusive vascular disease and long-standing complications. Case Summary We present the case of a patient with end-stage renal disease who presented for evaluation of chest pain and was found to have ST-segment myocardial infarction. Despite thrombectomy and stenting, he had multiple recurrent events, and imaging evaluation demonstrated caseous mitral annular calcification with mobile components. He was taken for surgical replacement of the mitral valve, with pathology confirming diagnosis. Discussion Caseous mitral annular calcification may represent an increased risk of embolic disease. Better understanding of this pathology and it’s propensity for embolic disease will be important to best determine treatment plans and timing of operative intervention.

Mitral annular calcification and valvular dysfunction: multimodality imaging evaluation, grading, and management

2021 ◽  
Author(s):  
Bo Xu ◽  
Duygu Kocyigit ◽  
Tom Kai Ming Wang ◽  
Carmela D Tan ◽  
E Rene Rodriguez ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Classification System ◽  
Multimodality Imaging ◽  
Imaging Modality ◽  
Cardiac Computed Tomography ◽  
Calcium Deposition ◽  
Mitral Annular Calcification ◽  
Imaging Evaluation ◽  
Line Imaging ◽  
Annular Calcification

Abstract Mitral annular calcification (MAC) refers to calcium deposition in the fibrous skeleton of the mitral valve. It has many cardiovascular associations, including mitral valve dysfunction, elevated cardiovascular risk, arrhythmias, and endocarditis. Echocardiography conventionally is the first-line imaging modality for anatomic assessment, and evaluation of mitral valve function. Cardiac computed tomography (CT) has demonstrated importance as an imaging modality for the evaluation and planning of related procedures. It also holds promise in quantitative grading of MAC. Currently, there is no universally accepted definition or classification system of MAC severity. We review the multimodality imaging evaluation of MAC and associated valvular dysfunction and propose a novel classification system based on qualitative and quantitative measurements derived from echocardiography and cardiac CT.

scholarly journals Point-of-care Ultrasound in the Evaluation of Mitral Valve Regurgitation and Mitral Annular Calcification

2020 ◽  
Vol 4 (4) ◽  
pp. 628-629
Author(s):  
Benjamen Schoenberg ◽  
Marwan Alkhattabi ◽  
Shadi Lahham
Keyword(s):  
Mitral Valve ◽  
Point Of Care ◽  
Mitral Valve Regurgitation ◽  
Point Of Care Ultrasound ◽  
Posterior Leaflet ◽  
Mitral Annular Calcification ◽  
Increased Risk ◽  
Valve Pathology ◽  
Annular Calcification

Case Presentation: A 77-year-old female presented to the emergency department (ED) with chest pain. Cardiac point-of-care ultrasound (POCUS) was performed and demonstrated a hyperechoic structure on the posterior leaflet of the mitral valve. Admission to cardiology and echocardiogram revealed moderately decreased mobility of the posterior leaflet, mitral annular calcification, and severe mitral regurgitation. Discussion: These findings highlight the role of POCUS in identifying mitral valve pathology in the ED, ultimately leading to appropriate disposition and management. Mitral annular calcification can lead to significant manifestations including mitral stenosis or regurgitation, and advanced cases have been associated with an increased risk of infective endocarditis, thrombosis, and arrhythmia.

scholarly journals Long-term outcome in a case of translocated mitral valve replacement for massive mitral annular calcification

2017 ◽  
Vol 5 (4) ◽  
pp. 454-457
Author(s):  
Go Kataoka ◽  
Kiyoharu Nakano ◽  
Ryota Asano ◽  
Atsuhiko Sato ◽  
Wataru Tatsuishi
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Mitral Annular Calcification ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Annular Calcification

Ultrasonic Emulsification of Severe Mitral Annular Calcification During Mitral Valve Replacement

2022 ◽  
Author(s):  
Alexander A. Brescia ◽  
Liza M. Rosenbloom ◽  
Tessa M.F. Watt ◽  
Curtis S. Bergquist ◽  
Aaron M. Williams ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Mitral Annular Calcification ◽  
Ultrasonic Emulsification ◽  
Annular Calcification

The Art of SAPIEN 3 Transcatheter Mitral Valve Replacement in Valve-in-Ring and Valve-in-Mitral-Annular-Calcification Procedures

2021 ◽  
Vol 14 (20) ◽  
pp. 2195-2214
Author(s):  
Vasilis C. Babaliaros ◽  
Robert J. Lederman ◽  
Patrick T. Gleason ◽  
Jaffar M. Khan ◽  
Keshav Kohli ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Mitral Annular Calcification ◽  
Transcatheter Mitral Valve Replacement ◽  
Sapien 3 ◽  
Annular Calcification

Acute-Phase Plasma PCSK9 Levels and Recurrent Cardiovascular Events in a Chinese Acute Myocardial Infarction Cohort

Cardiology ◽  
2018 ◽  
Vol 141 (2) ◽  
pp. 88-97 ◽  
Author(s):  
Yan Gao ◽  
Yan Qiu ◽  
Jihua Wu ◽  
Wei Diao ◽  
Haibo Zhang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Acute Phase ◽  
Recurrent Events ◽  
Density Lipoprotein ◽  
High Sensitivity ◽  
Female Gender ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Increased Risk

Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a promising target for lowering plasma low-density lipoprotein cholesterol and preventing cardiovascular (CV) disease. Whether plasma PCSK9 measured during the acute phase predicts recurrent CV events in patients with acute myocardial infarction (AMI) remains unresolved. Methods and Results: Plasma PCSK9 levels were measured in 1,646 patients with AMI from the China PEACE-Prospective AMI Study at the acute phase. Additionally, 248 patients were resampled and measured at 1 month post-AMI. Associations of acute-phase PCSK9 tertiles with clinical characteristics and recurrent CV events within 1 year were assessed. Female gender (OR 1.94, 95% CI 1.24–3.03), premature coronary heart disease (CHD; OR 2.12, 95% CI 1.37–3.26), higher high-sensitivity C-reactive protein (OR 1.67, 95% CI 1.44–1.95), and higher triglycerides (OR 1.46, 95% CI 1.03–2.09) were associated with higher baseline PCSK9. Plasma PCSK9 levels in the highest tertile (versus lowest) did not have an increased risk of 1-year recurrent CV events in the AMI cohort (HR 0.78, 95% CI 0.52–1.16) or any subgroup. There was also no association between percentage changes in PCSK9 over the first month and 1-year recurrent events, although there was a trend of differences between patients in the upper versus lower tertiles. Conclusion: Plasma PCSK9 levels measured during the acute phase were associated with high-sensitivity C-reactive protein, triglycerides, premature CHD, and gender in patients with AMI but did not predict recurrent CV events within 1 year. Dynamic changes in PCSK9 suggested a trend yet no significance value in predicting recurrent CV events.

scholarly journals Minimally invasive transatrial mitral valve replacement in mitral annular calcification

ASVIDE ◽  
2018 ◽  
Vol 5 ◽  
pp. 891-891
Author(s):  
Alexander P. Nissen ◽  
Joseph Lamelas ◽  
Isaac George ◽  
Juan Umana-Pizano ◽  
Tom C. Nguyen
Keyword(s):  
Mitral Valve ◽  
Minimally Invasive ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Mitral Annular Calcification ◽  
Annular Calcification
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