scholarly journals Echocardiographic indices of right heart function affecting ventilatory efficiency during exercise in left and right ventricular failure

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P670-P670
Author(s):  
M. Jasiewicz ◽  
M. Knapp ◽  
K. Ptaszynska ◽  
A. Szpakowicz ◽  
W. J. Musial ◽  
...  
2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Rohan Shad ◽  
Nicolas Quach ◽  
Robyn Fong ◽  
Patpilai Kasinpila ◽  
Cayley Bowles ◽  
...  

AbstractDespite progressive improvements over the decades, the rich temporally resolved data in an echocardiogram remain underutilized. Human assessments reduce the complex patterns of cardiac wall motion, to a small list of measurements of heart function. All modern echocardiography artificial intelligence (AI) systems are similarly limited by design – automating measurements of the same reductionist metrics rather than utilizing the embedded wealth of data. This underutilization is most evident where clinical decision making is guided by subjective assessments of disease acuity. Predicting the likelihood of developing post-operative right ventricular failure (RV failure) in the setting of mechanical circulatory support is one such example. Here we describe a video AI system trained to predict post-operative RV failure using the full spatiotemporal density of information in pre-operative echocardiography. We achieve an AUC of 0.729, and show that this ML system significantly outperforms a team of human experts at the same task on independent evaluation.


Medicina ◽  
2007 ◽  
Vol 43 (5) ◽  
pp. 432 ◽  
Author(s):  
Dagmara Reingardienė

Acute right ventricular failure is a syndrome, which is related to pulmonary and right heart dysfunction. It may occur with or without cardiopulmonary pathologies. It is often life threatening and requires early recognition and urgent treatment. In this review article, precipitating factors for right ventricular failure and its pathophysiological mechanisms, clinical picture and hemodynamic manifestations, the principles of the management of acute right ventricular failure (optimization of preload, increase in cardiac output, specific pulmonary vascular vasodilators, problems of mechanical ventilations, etc.) are discussed.


2010 ◽  
Vol 13 (1) ◽  
pp. 21
Author(s):  
Mustafa Pac ◽  
Aysenur Pac ◽  
Tugcin Bora Polat ◽  
Sevket Balli ◽  
Nesrin Turhan ◽  
...  

Right ventricular dysplasia is usually discovered by the presence of ventricular arrhythmia. As arrhythmia is an epiphenomenon, the first presentation of some cases can be primarily heart failure. We describe an adolescent girl who presented with progressive right heart failure and whose hallmark was fibrofatty replacement of ventricular muscle, especially of the right side, without ventricular arrhythmia. The patient was successfully treated by orthotopic heart transplantation.


2018 ◽  
Vol 54 (1) ◽  
pp. 75
Author(s):  
Fajar Perdhana ◽  
Herdono Purnomo

Right ventricular dysfunction and failure receive much less attention than the left ventricular failure. Right ventricular dysfunction or failure is associated with increased mortality rates in cardiac surgery, surgical cases other than cardiac surgery and also in patients treated in the ICU. The purpose of this article review was to describe the anatomy, physiology and pathophysiology of right ventricular failure, its detection and diagnosis, and management considerations from anesthetic point of view, including preoperative, intraoperative and postoperative stages. Cardiac surgery may result in right ventricular failure. For example, 0.1% post cardiotomy patients experience severe right heart failure and require long-term inotropic support, and so do 2-3% of post-transplant patients, and 20-30% of patients installed with instrument in his left heart. Therefore, anesthesiologists play a major role in perioperative and postoperative intensive care and are obliged to comprehend the nature of right ventricular dysfunction and failure so as to carry out early detection, prevent and manage patients with right ventricular dysfunction.


2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Wiebke Janssen ◽  
Yves Schymura ◽  
Tatyana Novoyatleva ◽  
Baktybek Kojonazarov ◽  
Mario Boehm ◽  
...  

Objective. The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-HT2B receptor antagonist) on right heart function and structure upon pulmonary artery banding (PAB) in mice.Methods. Seven days after PAB, mice were treated for 14 days with Terguride (0.2 mg/kg bid) or SB204741 (5 mg/kg day). Right heart function and remodeling were assessed by right heart catheterization, magnetic resonance imaging (MRI), and histomorphometric methods. Total secreted collagen content was determined in mouse cardiac fibroblasts isolated from RV tissues.Results. Chronic treatment with Terguride or SB204741 reduced right ventricular fibrosis and showed improved heart function in mice after PAB. Moreover, 5-HT2B receptor antagonists diminished TGF-beta1 induced collagen synthesis of RV cardiac fibroblastsin vitro.Conclusion. 5-HT2B receptor antagonists reduce collagen deposition, thereby inhibiting right ventricular fibrosis. Chronic treatment prevented the development and progression of pressure overload-induced RVF in mice. Thus, 5-HT2B receptor antagonists represent a valuable novel therapeutic approach for RVF.


Sign in / Sign up

Export Citation Format

Share Document