Presence of structural heart disease and left ventricular dysfunction predict hospitalizations for new-onset heart failure after right ventricular apical pacing

Abstract Background Heart failure (HF) is a major health problem. Cardiac and renal diseases interact in a complex bidirectional manner in both acute and chronic settings. Renal dysfunction in the setting of heart failure, termed the cardio renal syndrome (CRS), has been considered consequence of left ventricular dysfunction (LVD), whereby decreasing cardiac output (COP) results in renal under perfusion and consequent decreased glomerular filtration rate (GFR). Main body of the abstract This study showed that 500 patients were admitted to internal care unit (ICU), and out of them, 100 (20%) patients developed acute kidney injury (AKI) while 400 (80%) patients did not develop AKI. It is also showed that 67 (67%) of those with AKI and 100 (25%) of those with no-AKI had baseline ventricular systolic dysfunction, left ventricular dysfunction (LVD), right ventricular dysfunction (RVD), and biventricular dysfunction (BiVD)presented in 23 (23%), 16 (16%), and 28 (28%) patients of AKI group, respectively, and presented in 60 (15%), 30 (7.50%), and 10 (2.50%) patients, respectively, in patients without acute kidney injury (AKI) Short conclusion Our study revealed that AKI has highest incidence in patient with biventricular dysfunction followed by left ventricular dysfunction and lastly those with right ventricular dysfunction.

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New-Onset Heart Failure and Mortality in Hospital Survivors of Sepsis-Related Left Ventricular Dysfunction

Shock ◽

10.1097/shk.0000000000000952 ◽

2018 ◽

Vol 49 (2) ◽

pp. 144-149 ◽

Cited By ~ 23

Author(s):

Saraschandra Vallabhajosyula ◽

Jacob C. Jentzer ◽

Jeffrey B. Geske ◽

Mukesh Kumar ◽

Ankit Sakhuja ◽

...

Keyword(s):

Heart Failure ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Left Ventricular ◽

New Onset

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Left ventricular dysfunction in heart failure with preserved ejection fraction—molecular mechanisms and impact on right ventricular function

Cardiovascular Diagnosis and Therapy ◽

10.21037/cdt-20-477 ◽

2020 ◽

Vol 10 (5) ◽

pp. 1541-1560

Author(s):

Frank R. Heinzel ◽

Niklas Hegemann ◽

Felix Hohendanner ◽

Uwe Primessnig ◽

Jana Grune ◽

...

Keyword(s):

Heart Failure ◽

Ejection Fraction ◽

Right Ventricular ◽

Ventricular Function ◽

Left Ventricular Dysfunction ◽

Right Ventricular Function ◽

Molecular Mechanisms ◽

Ventricular Dysfunction ◽

Left Ventricular ◽

Preserved Ejection Fraction

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Left Ventricular Conduction Delays Induced by Right Ventricular Apical Pacing: Effect of Left Ventricular Dysfunction and Bundle Branch Block

Journal of Cardiovascular Electrophysiology ◽

10.1111/j.1540-8167.2007.00995.x ◽

2008 ◽

Vol 19 (2) ◽

pp. 114-122 ◽

Cited By ~ 48

Author(s):

NIRAJ VARMA

Keyword(s):

Right Ventricular ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Left Ventricular ◽

Bundle Branch Block ◽

Right Ventricular Apical Pacing ◽

Ventricular Conduction

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Right ventricular dysfunction and pulmonary hypertension: a neglected presentation of thyrotoxicosis

Endocrinology Diabetes and Metabolism Case Reports ◽

10.1530/edm-18-0012 ◽

2018 ◽

Vol 2018 ◽

Cited By ~ 2

Author(s):

Carolina Shalini Singarayar ◽

Foo Siew Hui ◽

Nicholas Cheong ◽

Goay Swee En

Keyword(s):

Heart Failure ◽

Pulmonary Hypertension ◽

Right Ventricular ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Right Ventricular Dysfunction ◽

Right Heart Failure ◽

Left Ventricular ◽

Newly Diagnosed ◽

Right Heart

Summary Thyrotoxicosis is associated with cardiac dysfunction; more commonly, left ventricular dysfunction. However, in recent years, there have been more cases reported on right ventricular dysfunction, often associated with pulmonary hypertension in patients with thyrotoxicosis. Three cases of thyrotoxicosis associated with right ventricular dysfunction were presented. A total of 25 other cases of thyrotoxicosis associated with right ventricular dysfunction published from 1994 to 2017 were reviewed along with the present 3 cases. The mean age was 45 years. Most (82%) of the cases were newly diagnosed thyrotoxicosis. There was a preponderance of female gender (71%) and Graves’ disease (86%) as the underlying aetiology. Common presenting features included dyspnoea, fatigue and ankle oedema. Atrial fibrillation was reported in 50% of the cases. The echocardiography for almost all cases revealed dilated right atrial and or ventricular chambers with elevated pulmonary artery pressure. The abnormal echocardiographic parameters were resolved in most cases after rendering the patients euthyroid. Right ventricular dysfunction and pulmonary hypertension are not well-recognized complications of thyrotoxicosis. They are life-threatening conditions that can be reversed with early recognition and treatment of thyrotoxicosis. Signs and symptoms of right ventricular dysfunction should be sought in all patients with newly diagnosed thyrotoxicosis, and prompt restoration of euthyroidism is warranted in affected patients before the development of overt right heart failure. Learning points: Thyrotoxicosis is associated with right ventricular dysfunction and pulmonary hypertension apart from left ventricular dysfunction described in typical thyrotoxic cardiomyopathy. Symptoms and signs of right ventricular dysfunction and pulmonary hypertension should be sought in all patients with newly diagnosed thyrotoxicosis. Thyrotoxicosis should be considered in all cases of right ventricular dysfunction or pulmonary hypertension not readily explained by other causes. Prompt restoration of euthyroidism is warranted in patients with thyrotoxicosis complicated by right ventricular dysfunction with or without pulmonary hypertension to allow timely resolution of the abnormal cardiac parameters before development of overt right heart failure.

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