premature ventricular complexes
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2022 ◽  
Author(s):  
muzakkir amir ◽  
Peter Kabo ◽  
Pendrik Tandean ◽  
Ilham Patellongi ◽  
Muchtar Siregar ◽  
...  

Abstract It is essential to enhance life quality in patients with premature ventricular complexes (PVCs) with the use of radiofrequency ablation (RFA). The aim of the study was to assess symptom burden and life quality in patients with a low PVC burden following RFA. 31 individuals with a low PVC burden in whom RFA was indicated were included in the study. At baseline and after a year following RFA, the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia (ASTA) scale was used for appraisal. A 24-hour Holter electrocardiogram was used to detect recurrent PVCs 12 months after the RFA intervention. ASTA scores related to symptom burden, including the near-syncope score, health-related quality of life (HRQOL) scales pertaining to physical and mental health, and consequently the total HRQOL score, were all diminished a year after RFA (p<0.001). The ASTA score for syncope symptoms was also reduced (p<0.05). A fall in mean PVC burden was seen from 8.0% to 0.8% (p<0.001). The long-term clinical endpoint in individuals with a low PVC burden following RFA is reported. Symptom load, life quality and ultimate PVC burden were all enhanced. Additional studies incorporating longer follow-up and monitoring periods, respectively, would be beneficial.


PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261712
Author(s):  
Sukardi Suba ◽  
Kirsten E. Fleischmann ◽  
Hildy Schell-Chaple ◽  
Priya Prasad ◽  
Gregory M. Marcus ◽  
...  

Background While there are published studies that have examined premature ventricular complexes (PVCs) among patients with and without cardiac disease, there has not been a comprehensive review of the literature examining the diagnostic and prognostic significance of PVCs. This could help guide both community and hospital-based research and clinical practice. Methods Scoping review frameworks by Arksey and O’Malley and the Joanna Briggs Institute (JBI) were used. A systematic search of the literature using four databases (CINAHL, Embase, PubMed, and Web of Science) was conducted. The review was prepared adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Review (PRISMA-ScR). Results A total of 71 relevant articles were identified, 66 (93%) were observational, and five (7%) were secondary analyses from randomized clinical trials. Three studies (4%) examined the diagnostic importance of PVC origin (left/right ventricle) and QRS morphology in the diagnosis of acute myocardial ischemia (MI). The majority of the studies examined prognostic outcomes including left ventricular dysfunction, heart failure, arrhythmias, ischemic heart diseases, and mortality by PVCs frequency, burden, and QRS morphology. Conclusions Very few studies have evaluated the diagnostic significance of PVCs and all are decades old. No hospital setting only studies were identified. Community-based longitudinal studies, which make up most of the literature, show that PVCs are associated with structural and coronary heart disease, lethal arrhythmias, atrial fibrillation, stroke, all-cause and cardiac mortality. However, a causal association between PVCs and these outcomes cannot be established due to the purely observational study designs employed.


Author(s):  
Serdar Demir ◽  
Kamil Gulsen ◽  
Alper Kepez ◽  
Abdulkadir Uslu ◽  
Ayhan Kup ◽  
...  

2021 ◽  
Author(s):  
Muzakkir Amir ◽  
Peter Kabo ◽  
Pendrik Tandean ◽  
Ilham Jaya Patellongi ◽  
Muchtar Nora Ismail Siregar ◽  
...  

Abstract Background: It is essential to enhance life quality in patients with premature ventricular complexes (PVCs) with the use of radiofrequency ablation (RFA). The aim of the study was to assess symptom burden and life quality in patients with a low PVC burden following RFA. Methods: 31 individuals with a low PVC burden in whom RFA was indicated were included in the study. At baseline and after a year following RFA, the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia (ASTA) scale was used for appraisal. A 24-hour Holter electrocardiogram was used to detect recurrent PVCs 12 months after the RFA intervention.Results: ASTA scores related to symptom burden, including the near-syncope score, healthrelated quality of life (HRQOL) scales pertaining to physical and mental health, and consequently the total HRQOL score, were all diminished a year after RFA (p<0.001). The ASTA score for syncope symptoms was also reduced (p<0.05). A fall in mean PVC burden was seen from 8.0% to 0.8% (p<0.001). Conclusion: The long-term clinical endpoint in individuals with a low PVC burden following RFA is reported. Symptom load, life quality and ultimate PVC burden were all enhanced. Additional studies incorporating longer follow-up and monitoring periods, respectively, would be beneficial.


2021 ◽  
Author(s):  
Pablo J. Sánchez‐Millán ◽  
Guillermo Gutiérrez‐Ballesteros ◽  
Manuel Molina‐Lerma ◽  
Rosa Macías‐Ruiz ◽  
Juan Jiménez‐Jáimez ◽  
...  

2021 ◽  
Vol 37 (10) ◽  
pp. S51-S52
Author(s):  
F Hosseini ◽  
G Gulsin ◽  
D Murphy ◽  
N Hawkins ◽  
J Andrade ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ahmed Sayed Tawfik ◽  
Ayman Morttada Abdelmoteleb ◽  
John Kamel Zarif ◽  
Emad Effat Fakhry

Abstract Background For localization of outflow tract Premature ventricular complexes (PVCs) many ECG criteria have been proposed, however in some cases it is difficult to accurately localize the origin of PVCs using the surface ECG. Objective This study aims to study the relation between QRS-right ventricular apex interval and the origin of the outflow tract PVCs. Patients and Methods The study included 30 patients (27 female, age 37.20 ± 7.87, RVOT origin 18) referred for PVCs ablation and we measured the interval from the onset of the earliest QRS complex of premature ventricular contractions (PVCs) to the distal right ventricular apical signal, (the QRS-RVA interval) and correlated this interval with origin of outflow tract PVCs as identified by the successful ablation during the procedure. Results Compared to PVCs originating from RVOT, the QRS-RVA interval was significantly longer in PVCs originating from LVOT (67.33±7.56 for LVOT PVCs vs. 37.11±4.34 for RVOT PVCs, p &lt; 0.001). Receiver operating characteristic (ROC) analysis showed that a QRSRVA interval ≥47 ms has a sensitivity, specificity, positive and negative predictive values of 100%, 100%, 100%, 100% respectively, for prediction of an LVOT origin of PVCs Conclusion The QRS-RVA interval is a simple and accurate criterion for differentiating the origin of outflow tract arrhythmia during electrophysiology study, A QRS-RVA interval ≥47 ms suggests an LVOT origin of PVCs.


Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S84
Author(s):  
Ankur N. Shah ◽  
Jasen L. Gilge ◽  
Brad Clark ◽  
Asim S. Ahmed ◽  
Saarik Gupta ◽  
...  

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