scholarly journals 16-01: ArcticLine: A New Cryo Ablation Catheter for the creation of Linear Lesions

EP Europace ◽  
2016 ◽  
Vol 18 (suppl_1) ◽  
pp. i1-i1
Author(s):  
Boaz Avitall ◽  
Arthur Kalinski ◽  
Teresa Mihalik ◽  
Alexandru Ionescu ◽  
Claudia Lueckge
Keyword(s):  
Ablation Catheter ◽  
Linear Lesions ◽  
The Creation ◽  
Cryo Ablation

The first testing of double balloon cryo ablation of PVs LA tissues for the creation of circumferential LA lesions

Heart Rhythm ◽  
2005 ◽  
Vol 2 (5) ◽  
pp. S196
Author(s):  
Boaz Avitall ◽  
Dinas Aleksonis ◽  
Daniel Lafontaine ◽  
Alexandru Chicos ◽  
Andrew Mykytsey
Keyword(s):  
Double Balloon ◽  
The Creation ◽  
Cryo Ablation

scholarly journals A09-1 A new improved 9FR, 8mm tip cryo ablation catheter for the treatment of atrial flutter

EP Europace ◽  
2003 ◽  
Vol 4 (Supplement_2) ◽  
pp. B13-B13
Author(s):  
A.S. Montenero ◽  
N. Bruno ◽  
F. Zumbo ◽  
D. Mangiameli ◽  
A. Antonelli ◽  
...  
Keyword(s):  
Atrial Flutter ◽  
Ablation Catheter ◽  
Cryo Ablation

scholarly journals β-Radiation for the Creation of Linear Lesions in the Canine Atrium

Circulation ◽  
2004 ◽  
Vol 110 (8) ◽  
pp. 911-914 ◽  
Author(s):  
Peter G. Guerra ◽  
Mario Talajic ◽  
Bernard Thibault ◽  
Marc Dubuc ◽  
Denis Roy ◽  
...  
Keyword(s):  
Linear Lesions ◽  
The Creation

scholarly journals Lattice-Tip Focal Ablation Catheter That Toggles Between Radiofrequency and Pulsed Field Energy to Treat Atrial Fibrillation

2020 ◽  
Vol 13 (6) ◽  
Author(s):  
Vivek Y. Reddy ◽  
Elad Anter ◽  
Gediminas Rackauskas ◽  
Petr Peichl ◽  
Jacob S. Koruth ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Radiofrequency Ablation ◽  
Pulmonary Vein ◽  
Pulmonary Vein Isolation ◽  
Diffusion Weighted Imaging ◽  
Persistent Atrial Fibrillation ◽  
Ablation Catheter ◽  
Pulsed Field ◽  
Linear Lesions ◽  
Fluid Attenuated Inversion Recovery

Background: The tissue selectivity of pulsed field ablation (PFA) provides safety advantages over radiofrequency ablation in treating atrial fibrillation. One-shot PFA catheters have been shown capable of performing pulmonary vein isolation, but not flexible lesion sets such as linear lesions. A novel lattice-tip ablation catheter with a compressible 9-mm nitinol tip is able to deliver either focal radiofrequency ablation or PFA lesions, each in 2 to 5 s. Methods: In a 3-center, single-arm, first-in-human trial, the 7.5F lattice catheter was used with a custom mapping system to treat paroxysmal or persistent atrial fibrillation. Toggling between energy sources, point-by-point pulmonary vein encirclement was performed using biphasic PFA posteriorly and either temperature-controlled irrigated radiofrequency ablation or PFA anteriorly (RF/PF or PF/PF, respectively). Linear lesions were created using either PFA or radiofrequency ablation. Results: The 76-patient cohort included 55 paroxysmal and 21 persistent atrial fibrillation patients undergoing either RF/PF (40 patients) or PF/PF (36 patients) ablation. The pulmonary vein isolation therapy duration time (transpiring from first to last lesion) was 22.6±8.3 min/patient, with a mean of 50.1 RF/PF lesions/patient. Linear lesions included 14 mitral (4 RF/2 RF+PF/8 PF), 34 left atrium roof (12 RF/22 PF), and 44 cavotricuspid isthmus (36 RF/8 PF) lines, with therapy duration times of 5.1±3.5, 1.8±2.3, and 2.4±2.1 min/patient, respectively. All lesion sets were acutely successful, using 4.7±3.5 minutes of fluoroscopy. There were no device-related complications, including no strokes. Postprocedure esophagogastroduodenoscopy revealed minor mucosal thermal injury in 2 of 36 RF/PF and 0 of 24 PF/PF patients. Postprocedure brain magnetic resonance imaging revealed diffusion-weighted imaging+/fluid-attenuated inversion recovery- and diffusion-weighted imaging+/fluid-attenuated inversion recovery+ asymptomatic lesions in 5 and 3 of 51 patients, respectively. Conclusions: A novel lattice-tip catheter could safely and rapidly ablate atrial fibrillation using either a combined RF/PF approach (capitalizing on the safety of PFA and the years of experience with radiofrequency energy) or an entirely PF approach. Registration: URL: https://www.clinicaltrials.gov ; Unique identifiers: NCT04141007 and NCT04194307.

P1448Ablation of cti-dependent flutter using a novel advanced mini-electrodes technology: preliminary results from Leonardo registry

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
G Maglia ◽  
F Pentimalli ◽  
F Solimene ◽  
T Infusino ◽  
L Calo" ◽  
...  
Keyword(s):  
Large Population ◽  
World Population ◽  
Ablation Catheter ◽  
Multicenter Cohort Study ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Ablation Time ◽  
The Creation

Abstract Funding Acknowledgements NO FUNDING OnBehalf LEONARDO study group Background Ablation of cavotricuspid isthmus (CTI) represents the standard therapeutic approach for the creation of bidirectional conduction block (BDB) across the isthmus and the prevention of recurrences, yet recurrence of arrhythmia is common. Objective To evaluate the acute and long-term outcome of CTI ablation through a novel ablation catheter equipped with three radially distributed mini-electrodes (ME) compared with standard ablation catheter technology (ST). Methods Atrial Flutter Ablation in a Real World Population (LEONARDO) is a prospective, multicenter cohort study aimed at providing an estimate of acute to long-term outcome in a large population of pts indicated for AFL ablation from 2015 to 2017. The procedural endpoint was the creation of a BDB. Presence of widely split double potentials (DP) along the ablation line and assessment of the atrial activation sequence (AAS) were used as criteria for complete BDB. Recurrence of AFL and complications were assessed at 12-month follow-up. Results   205 consecutive pts undergoing typical AFL ablation were included (74% male, 50.6% with history of AF, median of 7[4–11] ablation lesions, median ablation time of 20[10-30] min). Complete BDB was achieved in 175 (85.4%) pts (10 pts had DP only criterion, 19 pts had AAS only criterion whereas in 1 pt we failed to reach a BDB). 15 (7.3%) pts experienced AFL recurrence during follow-up. 102 pts (49.8%) underwent ablation procedure with ME catheters whereas 103 (50.2%) pts were treated by ST catheters. The median number of lesions/pt was significantly lower in the ME group compared to the ST one (4[3-6] vs 8.5[6-12], p < 0.0001), whereas no differences were found in terms of fluoroscopy time (10.5[7-15] min vs 10[5.8 ± 15] min, p = NS) or ablation time (22.5[10-30.5] min vs 18[10-26] min, p = NS). No complications were reported. The acute procedural success was comparable between groups (81.4% vs 89.2%, p = NS) whereas the time to AFL recurrence was significantly longer among pts targeted with ME catheters (HR = 0.343; 0.12 to 0.97; log-rank p = 0.044). Conclusions In our preliminary experience, the use of the ME technology seemed safe and effective. It resulted in fewer lesions/pt and a lower AFL recurrence rate at 1-year follow-up compared with ST ablation catheters.

The role of affect in feelings of obligation

2020 ◽  
Vol 43 ◽  
Author(s):  
Stefen Beeler-Duden ◽  
Meltem Yucel ◽  
Amrisha Vaish
Keyword(s):  
Positive Emotions ◽  
The Creation ◽  
Sense Of Obligation

Abstract Tomasello offers a compelling account of the emergence of humans’ sense of obligation. We suggest that more needs to be said about the role of affect in the creation of obligations. We also argue that positive emotions such as gratitude evolved to encourage individuals to fulfill cooperative obligations without the negative quality that Tomasello proposes is inherent in obligations.

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