Multimorbidity patterns and quality of life across European populations: Results from SHARE database

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
T T Makovski ◽  
B Poblador Plou ◽  
M Schnell ◽  
S Stranges ◽  
M Zeegers ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Large Population ◽  
Population Based ◽  
Common Disease ◽  
Cross Sectional ◽  
Complex Needs ◽  
Disease Patterns ◽  
Suboptimal Care ◽  
Sectional Analysis

Abstract An increasing number of people living with multimorbidity may receive suboptimal care since health systems are not well prepared to respond to their complex needs. Identifying which conditions most commonly group together could support better care for patients with multiple diseases. This is particularly critical for conditions that have the most deteriorating effect on quality of life (QoL). The aim of the study was to: 1) identify multimorbidity patterns in Europe and 2) assess their impact on QoL. This was a cross-sectional analysis performed on the Survey of Health, Ageing and Retirement in Europe (SHARE) among adults aged 50+, in eighteen countries (n = 67,179). The Control, Autonomy, Self-Realization and Pleasure (CASP-12v1) scale assessed QoL. Exploratory factor analysis (using 17 conditions) based on tetra-choric correlations, was applied to identify multimorbidity patterns. Associations between patterns and QoL were estimated with multilevel mixed-effects linear regression. The analyses were adjusted for socio-economic, clinical and psycho-social factors, and stratified by sex. Three multimorbidity patterns were found: 1) cardio-metabolic [frequency in men (27.7%); women (25.9%)], 2) psycho-geriatric [1.4%; 0.3%] and 3) mixed [11.7%; 17.4%]. Sample adequacy was confirmed by the Kaiser-Meyer-Olkin test [0.81; 0.84, for men and women, respectively]. The patterns showed slight sex differences. The frequency of all patterns increased with age, while patterns overlapped significantly in the population. The psycho-geriatric pattern had the most deteriorating effect on QoL [-4.5(95%CI:-6.2;-2.8) for men; -5.0(95%CI: -9.5; -0.5) for women]. Recognizing the most common disease patterns may allow more targeted planning and provision of care, including development of clinical guidelines, enhancing collaboration between health professionals, and creation of prevention plans to reduce complications and preserve the best QoL for patients with multimorbidity. Key messages First large population-based study on multimorbidity patterns and their impact on QoL across Europe, using SHARE database. The findings can serve to support better care for multimorbid patients.

scholarly journals Impact of repeat flooding on mental health and health-related quality of life: a cross-sectional analysis of the English National Study of Flooding and Health

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e031562 ◽  
Author(s):  
Clare E French ◽  
Thomas D Waite ◽  
Ben Armstrong ◽  
G. James Rubin ◽  
Charles R Beck ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
National Study ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related ◽  
Sectional Analysis ◽  
Probable Depression

ObjectiveTo assess the association between flooding/repeat flooding and: (1) psychological morbidity (anxiety, depression, post-traumatic stress disorder (PTSD)) and (2) health-related quality of life (HRQoL) at 6 months post-flooding.DesignCross-sectional analysis of data from the English National Study of Flooding and Health.SettingCumbria, England.ParticipantsQuestionnaires were sent to 2500 residential addresses at 6 months post-flooding; 590 people responded.OutcomesProbable depression was assessed using the Patient Health Questionnaire, probable anxiety using the Generalised Anxiety Disorder scale and probable PTSD using the short-form PTSD checklist (PCL-6). HRQoL was assessed using the EQ-5D-5L. Mental health outcomes were analysed using logistic regression; HRQoL dimensions using ordinal regression; and summary index/Visual Analogue Scale scores using linear regression.ResultsOne hundred and nineteen participants had been flooded, over half of whom were experiencing a repeat flooding event (54%; n=64). Mental health outcomes were elevated among flooded compared with unaffected participants (adjusted OR for probable depression: 7.77, 95% CI: 1.51 to 40.13; anxiety: 4.16, 95% CI: 1.18 to 14.70; PTSD: 14.41, 95% CI: 3.91 to 53.13). The prevalence of depression was higher among repeat compared with single flooded participants, but this was not significant after adjustment. There was no difference in levels of anxiety or PTSD. Compared with unaffected participants, those flooded had lower EQ-5D-5L index scores (adjusted coefficient: −0.06, 95% CI: −0.12 to −0.01) and lower self-rated health scores (adjusted coefficient: −6.99, 95% CI: −11.96 to −2.02). There was, however, little difference in HRQoL overall between repeat and single flooded participants.ConclusionsInterventions are needed to help minimise the impact of flooding on people’s mental health and HRQoL.

Prevalence and Associated Factors of Sarcopenia and Frailty in Parkinson’s Disease: A Cross-Sectional Study

Gerontology ◽  
2018 ◽  
Vol 65 (3) ◽  
pp. 216-228 ◽  
Author(s):  
Marina Peball ◽  
Philipp Mahlknecht ◽  
Mario Werkmann ◽  
Kathrin Marini ◽  
Franziska Murr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Population Based ◽  
Cross Sectional Study ◽  
Prevalence Rates ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tertiary Center

Background: Sarcopenia and frailty are found in up to one-third of the general elderly population. Both are associated with major adverse health outcomes such as nursing home placement, disability, decreased quality of life, and death. Data on the frequency of both syndromes in Parkinson’s disease (PD), however, are very limited. Objective: We aimed to screen for sarcopenia and frailty in PD patients and to assess potential associations of both geriatric syndromes with demographic and clinical parameters as well as quality of life. Methods: In this observational, cross-sectional study, we included 104 PD patients from a tertiary center and 330 non-PD controls from a population-based cohort aged > 65 years. All groups were screened for sarcopenia using the SARC-F score and for frailty using the Clinical Frailty Scale of the Canadian Study of Health and Aging (CSHA CFS). Prevalence rates of sarcopenia and frailty were also assessed in 18 PD patients from a population-based cohort aged > 65 years. Moreover, PD patients from the tertiary center were evaluated for motor and non-motor symptoms, quality of life, and dependency. Results: The prevalence of sarcopenia was 55.8% (95% CI: 46.2–64.9%) in PD patients from the tertiary center and 8.2% (5.7–11.7%; p < 0.001) in non-PD controls. Frailty was detected in 35.6% (27.0–45.2%) and 5.2% (3.2–8.1%; p < 0.001). Prevalence rates for sarcopenia and frailty were 33.3% (16.1–56.4%; p = 0.004) and 22.2% (8.5–45.8%; p = 0.017) in the community-based PD sample. Both sarcopenia and frailty were significantly associated with longer disease duration, higher motor impairment, higher Hoehn and Yahr stages, decreased quality of life, higher frequency of falls, a higher non-motor symptom burden, institutionalization, and higher care levels in PD patients from a tertiary center compared to not affected PD patients (all p < 0.05). Conclusions: Both frailty and sarcopenia are more common in PD patients than in the general community and are associated with a more adverse course of the disease. Future studies should look into underlying risk factors for the occurrence of sarcopenia and frailty in PD patients and into adequate management to prevent and mitigate them.

Forced Vital Capacity and Quality of Life: BOLD Study Cross-Sectional Analysis

2021 ◽  
Author(s):  
Emmanouil Bagkeris ◽  
Jaymini Patel ◽  
Christer Janson ◽  
Andre Amaral ◽  
Peter Burney
Keyword(s):  
Quality Of Life ◽  
Forced Vital Capacity ◽  
Vital Capacity ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

scholarly journals Relationship between dental fluorosis and quality of life: a population based study

2005 ◽  
Vol 19 (2) ◽  
pp. 150-155 ◽  
Author(s):  
Edgard Michel-Crosato ◽  
Maria Gabriela Haye Biazevic ◽  
Edgard Crosato
Keyword(s):  
Quality Of Life ◽  
Water Supply ◽  
Dental Fluorosis ◽  
Female Gender ◽  
Population Based ◽  
Daily Activities ◽  
Cross Sectional ◽  
Significance Level ◽  
The Impact

The aim of this study was to verify the prevalence of dental fluorosis in schoolchildren aged 6 to 15 and its possible association with the impacts on their daily activities. This study is observational, cross-sectional and analytical. A total of 513 schoolchildren from the city of Pinheiro Preto, SC, took part in this study. The children were examined by three calibrated dentists, after obtaining a kappa > 0.80. To assess the prevalence of fluorosis, clinical examinations were performed according to the methodology set forth by the 4th edition of the WHO. To assess the impact of fluorosis on their daily activities, a modified OIDP (Oral Impacts on Daily Performance) was adopted. The statistical analysis used was the Chi-squared test with a 5% significance level. Of the total number of children examined, 262 (51.1%) were of the female gender and 251 (48.9%) were of the male gender. In regard to the prevalence of fluorosis, 94 (18.3%) of the children presented this condition, while 419 children (81.7%) presented a normal condition. In regard to the severity of fluorosis, few children presented severe alterations. No association was found between dental fluorosis and gender (p = 0.646), between fluorosis and socioeconomic status (p = 0.848) or between fluorosis and access to public water supply system (p = 0.198). The activities that most affected children's daily performance were: oral hygiene (40.9%) and food intake or enjoying food (40.4%). None of the daily activities could be associated with the occurrence of dental fluorosis. The prevalence of dental fluorosis was consonant with the standards found for locations with optimum fluoride content in the water supply. The questionable and very slight levels of fluorosis were the most frequently found, without influence in the quality of life of the schoolchildren participating in the study.

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