scholarly journals Contribution of overweight/obesity to adverse pregnancy outcomes in immigrant and non-immigrant women

2015 ◽  
Vol 25 (suppl_3) ◽  
Author(s):  
O Razum ◽  
K Reiss ◽  
J Breckenkamp ◽  
T Borde ◽  
S Brenne ◽  
...  
2021 ◽  
Author(s):  
Mouctar Sow ◽  
Myriam De Spiegelaere ◽  
Marie-Pierre Sylvestre ◽  
Marie-France Raynault

Abstract Background The risk of unfavourable pregnancy outcomes for immigrant mothers varies according to their birthplace, socioeconomic status (SES) and comparison group. This study aims to identify the characteristics of Montreal newborns who are more or less at risk of LBW, prematurity and SGA, according to the mother's birthplace and SES. Methods The analysis focuses on all singleton live births in Montreal between 2003 and 2012 (N=214,620). Logistic regression models were estimated using generalized estimating equations in order to: 1) compare the risk of adverse pregnancy outcomes between Canadian-born and immigrant mothers. The latter were categorised into 8 groups according to world regions; 2) estimate the odds ratio of the association between adverse pregnancy outcomes and the mother's SES (education and income quintile) for each group. Results The risk of LBW, prematurity and SGA vary considerably depending on the mother’s birthplace. For these three outcomes, mothers from the Caribbean and South Asia have a higher prevalence than all other groups. Three other groups compare favourably to Canadian-born mothers: mothers from North Africa, Europe & the USA, and Central and West Asia. The association between SES and unfavourable pregnancy outcomes varies from one group of mothers to another. Among Canadian-born mothers, there is a classic health gradient, with low SES mothers being particularly vulnerable. While income is not associated with the risk of adverse outcomes among immigrant mothers, education is for many groups. The association is however weaker than for Canadian-born mothers. Conclusions It is important to assess the influence of both immigration and SES to better identify the children who are most at risk of experiencing perinatal health concerns. In Montreal, some immigrant women are particularly vulnerable, but so are socioeconomically disadvantaged native Canadian women. Conversely, North African-born mothers with low SES present a particularly low risk. It has also been found that a high level of education reduces the risk among several groups of immigrant women, as opposed to findings in other contexts.


2015 ◽  
Vol 25 (5) ◽  
pp. 839-844 ◽  
Author(s):  
Katharina Reiss ◽  
Jürgen Breckenkamp ◽  
Theda Borde ◽  
Silke Brenne ◽  
Matthias David ◽  
...  

2020 ◽  
Vol 26 ◽  
Author(s):  
Yang Zhang ◽  
Dandan Li ◽  
Heng Guo ◽  
Weina Wang ◽  
Xingang Li ◽  
...  

Background: Conflicting data exist regarding the influence of thiopurines exposure on adverse pregnancy outcomes in female patients with inflammatory bowel disease (IBD). Objective: The aim of this study was to provide an up-to-date and comprehensive assessment of the safety of thiopurines in pregnant IBD women. Methods: All relevant articles reporting pregnancy outcomes in women with IBD received thiopurines during pregnancy were identified from the databases (PubMed, Embase, Cochrane Library, and ClinicalTrials.gov) with the publication data up to April 2020. Data of included studies were extracted to calculate the relative risk (RR) of multiple pregnancy outcomes: congenital malformations, low birth weight (LBW), preterm birth, small for gestational age (SGA), and spontaneous abortion. The meta-analysis was performed using the random-effects model. Results: Eight studies matched with the inclusion criteria and a total of 1201 pregnant IBD women who used thiopurines and 4189 controls comprised of women with IBD received drugs other than thiopurines during pregnancy were included. Statistical analysis results demonstrated that the risk of preterm birth was significantly increased in the thiopurine-exposed group when compared to IBD controls (RR, 1.34; 95% CI, 1.00-1.79; p=0.049; I 2 =41%), while no statistically significant difference was observed in the incidence of other adverse pregnancy outcomes. Conclusion: Thiopurines’ use in women with IBD during pregnancy is not associated with congenital malformations, LBW, SGA, or spontaneous abortion, but appears to have an association with an increased risk of preterm birth.


Author(s):  
Shamil D. Cooray ◽  
Jacqueline A. Boyle ◽  
Georgia Soldatos ◽  
Shakila Thangaratinam ◽  
Helena J. Teede

AbstractGestational diabetes mellitus (GDM) is common and is associated with an increased risk of adverse pregnancy outcomes. However, the prevailing one-size-fits-all approach that treats all women with GDM as having equivalent risk needs revision, given the clinical heterogeneity of GDM, the limitations of a population-based approach to risk, and the need to move beyond a glucocentric focus to address other intersecting risk factors. To address these challenges, we propose using a clinical prediction model for adverse pregnancy outcomes to guide risk-stratified approaches to treatment tailored to the individual needs of women with GDM. This will allow preventative and therapeutic interventions to be delivered to those who will maximally benefit, sparing expense, and harm for those at a lower risk.


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