Clinical application of projection mapping technology for surgical resection of lung metastasis

Teaching materials that can interactively display the vectors of forces and velocities as well as the trajectories and graphs of remarkable points, which are invisible in actual mechanical movements, should be capable of effectively supporting the learning of complex robot mechanics. In this study, we aim to acquire knowledge about the design principles for building teaching materials for robot mechanics, applying projection mapping technology (PM). We have first studied the components required in teaching material systems on the following candidate mechanisms: transmission mechanism with spur gears and quadric crank chain as two basic mechanisms and serial two-link mechanism as a representative subject of robot mechanisms. We have constructed systems and conducted experiments to evaluate their performance. In this study, we propose a fundamental method for designing teaching materials on mechanisms applying PM, establish the effectiveness of the proposed method, and indicate problems with the current systems.

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Photodynamic assisted surgical resection and treatment of malignant brain tumours technique, technology and clinical application

Photodiagnosis and Photodynamic Therapy ◽

10.1016/s1572-1000(04)00014-6 ◽

2004 ◽

Vol 1 (1) ◽

pp. 93-98 ◽

Cited By ~ 17

Author(s):

M.Sam Eljamel

Keyword(s):

Surgical Resection ◽

Clinical Application ◽

Brain Tumours ◽

Malignant Brain Tumours

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Clinical outcomes of surgical resection for recurrent lesion after curative esophagectomy for esophageal squamous cell carcinoma: a nationwide, large-scale retrospective study

Esophagus ◽

10.1007/s10388-021-00878-2 ◽

2021 ◽

Author(s):

Kensuke Kudou ◽

Hiroshi Saeki ◽

Yuichiro Nakashima ◽

Yasue Kimura ◽

Eiji Oki ◽

...

Keyword(s):

Overall Survival ◽

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Surgical Resection ◽

Lung Metastasis ◽

Squamous Cell ◽

R0 Resection ◽

Free Interval ◽

Curative Esophagectomy

Abstract Background Several studies have reported the efficacy of resection for recurrent lesions. However, they involved a limited number of subjects. This study aimed to identify a subset of patients who benefit from surgical resection of recurrent lesions after curative esophagectomy for esophageal squamous cell carcinoma. Methods Clinicopathological features of 186 patients with esophageal squamous cell carcinoma who underwent surgical treatment for postoperative recurrent lesions at 37 accredited institutions of the Japanese Esophageal Society were evaluated. Results The most common recurrence site was the lymph node (106 cases; 58.6%), followed by the lung (40 cases; 22.1%). Univariate analyses revealed that pN 0–1 at esophagectomy (P = 0.0348), recurrence-free interval of ≥ 550 days (P = 0.0306), R0 resection (P < 0.0001), and absence of severe complications after resection for recurrent lesions (Clavien–Dindo grade < IIIa) (P = 0.0472) were associated with better overall survival after surgical resection. According to multivariate analyses, pN 0–1 (P = 0.0146), lung metastasis (P = 0.0274), recurrence-free interval after curative esophagectomy of ≥ 550 days (P = 0.0266), R0 resection (P = 0.0009), and absence of severe complications after resection for recurrent lesions (Clavien–Dindo grade < IIIa) (P = 0.0420) were independent predictive factors for better overall survival. Conclusions Surgical resection of recurrent esophageal squamous cell carcinoma lesions is a useful option, especially for cases involving lower pN stage, lung metastasis, long recurrence-free intervals after esophagectomy, and technically resectable lesions. Surgical risks should be minimized as much as possible.

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Fluorescent Nanoparticles for the Guided Surgery of Ovarian Peritoneal Carcinomatosis

Nanomaterials ◽

10.3390/nano8080572 ◽

2018 ◽

Vol 8 (8) ◽

pp. 572 ◽

Cited By ~ 6

Author(s):

Tristan Mangeolle ◽

Ilya Yakavets ◽

Sophie Marchal ◽

Manon Debayle ◽

Thomas Pons ◽

...

Keyword(s):

Peritoneal Carcinomatosis ◽

Fluorescence Imaging ◽

Surgical Resection ◽

Clinical Application ◽

Short Wave ◽

Fluorescent Nanoparticles ◽

Guided Surgery ◽

Complete Surgical Resection ◽

Short Wave Infrared ◽

The Ideal

Complete surgical resection is the ideal cure for ovarian peritoneal carcinomatosis, but remains challenging. Fluorescent guided surgery can be a promising approach for precise cytoreduction when appropriate fluorophore is used. In the presence paper, we review already developed near- and short-wave infrared fluorescent nanoparticles, which are currently under investigation for peritoneal carcinomatosis fluorescence imaging. We also highlight the main ways to improve the safety of nanoparticles, for fulfilling prerequisites of clinical application.

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Clinical Application of Direct Bronchial Ultrasound to Visualize and Determine Endobronchial Tumor Margins for Surgical Resection

The Annals of Thoracic Surgery ◽

10.1016/j.athoracsur.2008.04.115 ◽

2008 ◽

Vol 86 (4) ◽

pp. 1339-1341 ◽

Cited By ~ 5

Author(s):

Khaled M. Sarraf ◽

Elizabeth Belcher ◽

Susanna Price ◽

Eric Lim

Keyword(s):

Surgical Resection ◽

Clinical Application ◽

Tumor Margins

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Curative Radiotherapy using Different Radiation Techniques for Isolated Lung Metastasis from Colorectal Cancer

Tumori Journal ◽

10.1177/030089161309900112 ◽

2013 ◽

Vol 99 (1) ◽

pp. 68-75 ◽

Cited By ~ 2

Author(s):

Sunyoung Lee ◽

Dae Yong Kim ◽

Sun Young Kim ◽

Woong Sub Koom ◽

Sun Young Lee ◽

...

Keyword(s):

Colorectal Cancer ◽

Prognostic Factors ◽

Treatment Response ◽

Surgical Resection ◽

Lung Metastasis ◽

Local Control ◽

Relapse Free Survival ◽

Free Survival ◽

Curative Radiotherapy ◽

Isolated Lung

Aims and background Surgical resection remains the mainstay for the treatment of colorectal lung metastasis, but a group of patients who are medically inoperable or unsuitable for surgery are treated with radiotherapy. The purpose of this multi-institutional study was to evaluate the clinical outcome and investigate the prognostic factors affecting local control and survival in this subset of patients. Methods We retrospectively analyzed 30 patients with 43 lesions who underwent curative radiotherapy for isolated lung metastasis from colorectal cancer at nine institutions from 2003 and 2008. A total dose of 42–75 Gy at the peripheral planning target volume was administered in 3–35 fractions. The median biologically equivalent dose was 84 Gy (range, 58.5–180). Results Treatment response was complete in 10 (33.3%), partial in 13 (43.3%), stable in six (20.0%), and progressive in one patient (3.3%). The median follow-up period for all patients was 29.0 months (range, 5.0–93.8). Kaplan-Meier local control at 5 years was 44%. The median survival was 46.2 months, and the 5-year overall survival was 47%. Twenty-three patients (77%) experienced treatment failure, most of which were intrapulmonary failure. The intrapulmonary relapse-free survival and overall relapse-free survival at 5 years were 22% and 19%, respectively. Treatment response and pre-radiotherapy carcinoembryonic antigen level were significant prognostic factors for local control and survival. Grade 3–5 toxicity occurred in 7 patients. Three patients had grade 5 toxicity, including radiation pneumonitis, a tracheoesophageal fistula, and hemoptysis. Conclusions Curative radiotherapy for isolated lung metastasis from colorectal cancer in patients who are medially inoperable or unsuitable for surgery results in long-term survival, comparable to surgical resection. Curative radiotherapy could be an effective and noninvasive alternative if dose-limiting toxicity is carefully considered, particularly in patients with bilateral or central lesions.

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