Delayed Neurological Sequelae in an Infant after Carbon Monoxide Intoxication

2021 ◽  
Author(s):  
Yeu-Her Lai ◽  
Li-Wen Chen ◽  
Yuan-Yu Hsueh
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning ◽  
Fetal Hemoglobin ◽  
Neurologic Examination ◽  
Neurological Sequelae ◽  
Carbon Monoxide Intoxication ◽  
Prompt Treatment ◽  
Age Appropriate ◽  
Tongue Thrust ◽  
Acute Event

Abstract Delayed neurological sequelae are symptoms that appear over a period of time after an acute event of carbon monoxide poisoning. The incidence of delayed neurological sequelae is lower in children than in adults and is even more uncommon in infants. Here, we present a case of a 4-month-old infant who developed delayed neurological sequelae after carbon monoxide intoxication. She presented with neurologic symptoms, including opisthotonus, athetoid movements, anterior tongue thrust, and opsoclonus. Because these symptoms are starkly different from those of adults, they should be compared with age-appropriate developmental milestones. Because of their faster metabolic rate and presence of fetal hemoglobin, infants with developing brains may be especially vulnerable to carbon monoxide toxicity. Therefore, thorough neurologic examination and prompt treatment are critical for infants who experience carbon monoxide intoxication.

Study of Carbon Monoxide Intoxication in Fire Victimis

2018 ◽  
Vol 68 (12) ◽  
pp. 2932-2935
Author(s):  
Sofia David ◽  
Anton Knieling ◽  
Calin Scripcaru ◽  
Madalina Diac ◽  
Ion Sandu ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning ◽  
Inverse Correlation ◽  
Blood Samples ◽  
Mortality And Morbidity ◽  
Carbon Monoxide Intoxication ◽  
Gas Poisoning ◽  
The World ◽  
Fire Victims ◽  
In Fire

Carbon monoxide poisoning is the leading cause of mortality and morbidity of toxic origin in the world. Its insidious and polymorphic symptomatology makes it difficult to diagnose. It occurs accidentally, because of non-supervised domestic fires, or in fire victims. In fire victims, in particular, the differential diagnosis between carbon monoxide gas poisoning, inhalation of other toxic products of combustion like cyanide, oxygen deprivation, thermal burns and shock due to burns as a cause of death is not an easy task. The authors examined 107 fire victims that were autopsied at the Forensic Medicine from Iasi, Romania, in the last 10 years (2007-2016). Most cases were males (69.16%), young (0-9 years) or older than 60 with a burned surface of 91-100% in 68.22% of cases. Blood samples from the cadavers were collected in all cases in order to analyse carboxyhaemoglobin concentration and haemolysis. Toxicological analysis revealed a carboxyhaemoglobin level of maximum 95% but the majority of cases (70.72%) had a concentration inferior to 50%. An inverse correlation was identified between carboxyhaemoglobin concentration and haemolysis, an indicator of heat dissociation. Our study proves that many fire victims may die because of carbon monoxide intoxication prior to the extent of burns at a lethal potential.

scholarly journals Delayed Neurological Sequelae Following Carbon Monoxide Poisoning and Skin Graft: A Case Report

2020 ◽  
Vol 5 (4) ◽  
pp. 164-167
Author(s):  
Reza Bidaki ◽  
Azadeh Rahavi ◽  
Farzaneh Dehghani ◽  
Mohamad Ebrahim Ghanei ◽  
Najmeh Zaer-Alhosseini ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Case Report ◽  
Skin Graft ◽  
Carbon Monoxide Poisoning ◽  
Neurological Sequelae

Neurological Sequelae of Carbon Monoxide Poisoning: Role of Hyperbaric Oxygen

1995 ◽  
Vol 4 (3-4) ◽  
pp. 134-139
Author(s):  
Raffaella Butera ◽  
Stefano M. Candura ◽  
Carlo Locatelli ◽  
Concettina Varango ◽  
Bin Li ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Hyperbaric Oxygen ◽  
Carbon Monoxide Poisoning ◽  
Neurological Sequelae

scholarly journals Urgent cesarean section in a pregnant woman with carbon monoxide poisoning

2014 ◽  
Vol 155 (22) ◽  
pp. 871-875
Author(s):  
Edit Gara ◽  
Éva Gesztes ◽  
Richárd Doroszlai ◽  
Gábor Zacher
Keyword(s):  
Carbon Monoxide ◽  
Pregnant Woman ◽  
Cesarean Section ◽  
Oxygen Therapy ◽  
Carbon Monoxide Poisoning ◽  
Chemical Properties ◽  
Heating Systems ◽  
Carbon Monoxide Intoxication ◽  
Non Invasive ◽  
Physical Chemical

Recognition of carbon monoxide is difficult due to its plain physical-chemical properties. Carbon and gas operating heating systems may cause severe poisoning. Carbon-monoxide intoxication may generate severe hypoxic damage and it may cause death. The authors present the case of severe carbon monoxide poisoning affecting one young child and five adults, including a pregnant woman. Because the availability of hyperbaric oxygen therapy is limited in Hungary, urgent cesarean section was performed to avoid intrauterine hypoxic damage. The authors note that there are no standardized non-invasive methods for measuring fetal carbon-monoxide level and that the level of carbon monoxide accumulation is higher and the clearance is longer in the fetus than in the mother. The pathophysiology of carbon monoxide intoxication and therapeutic options in pregnancy are discussed. Orv. Hetil., 2014, 155(22), 871–875.

Current and research therapies for the prevention and treatment of delayed neurological syndrome associated with carbon monoxide poisoning: A narrative review

2020 ◽  
Vol 39 (6) ◽  
pp. 765-772
Author(s):  
B del Moral-Barbudo ◽  
R Blancas ◽  
D Ballesteros-Ortega ◽  
M Quintana-Díaz ◽  
Ó Martínez-González
Keyword(s):  
Carbon Monoxide ◽  
Hyperbaric Oxygen ◽  
Carbon Monoxide Poisoning ◽  
Narrative Review ◽  
Co Poisoning ◽  
Common Environment ◽  
Neurological Sequelae ◽  
Neurological Syndrome ◽  
Oxygen Administration ◽  
Prevention And Treatment

Severe carbon monoxide (CO) poisoning causes fulminant deaths in common environment as well as neurological sequelae to survivors. Prevention of delayed neurological syndrome (DNS) after exposure to CO, the most important sequela, is based up to date on hyperbaric oxygen administration. Nevertheless, its use remains controversial due to the lack of evidence regarding its efficacy. The aim of this review is to report therapies under investigation for preventing or improving DNS, some of them with promising results in humans.

Sign in / Sign up

Export Citation Format

Share Document