Age-specific prostate cancer incidence rate in the world

183 Background: Prostate cancer has long been considered as a disease of older men. However, age at diagnosis with prostate cancer has continued to decline. Since the introduction of prostate-specific antigen (PSA) test in 1986, the prostate cancer incidence rate has steadily and dramatically increased in men under age 50. This study aims to better understand demographic variations in prostate cancer screening and incidence, and clinical characteristics of prostate cancers in men under age 50. Methods: We examined prostate cancer testing data from the Behavioral Risk Factor Surveillance System (2002, 2004, 2006, and 2008) and prostate cancer incidence data from the CDC's National Program of Cancer Registries and the NCI's Surveillance, Epidemiology, and End Results programs (2001-2006). We estimated the weighted percentage of self-reported cancer testing using SUDAAN and age-adjusted cancer incidence rates and trends using SEER-STAT. Statistical significance for trends was determined by the annual percentage change (APC) differing form zero. Results: A total of 29,176 prostate cancer cases were identified from 2001-2006 among men under age 50. Of these, 551 (1.9%) were among men under age 40. Incidence rates remained stable from 2001-2006; however the incidence of well-differentiated tumors decreased significantly (APC=−24.7) during this time period. About 44% of men aged 40-49 years old reported having a prostate cancer test in the past two years. Prostate cancer testing and incidence rates were highest among men who were black, non-Hispanic, or lived in the northeast. Black men had more than a 2-fold increase in cancer incidence than white men. Conclusions: The magnitude of prostate cancer testing and incidence in men under age 50 reveals significant health/public health problems in this younger population. This study demonstrates substantial regional differences in prostate cancer testing and incidence in men under age 50. It also confirms that prostate cancer testing and incidence varies by race and ethnicity. We observed a large disparity in prostate cancer incidence between blacks and whites. The incidence rate remained stable over time; the dramatic decrease occurred in well-differentiated cancers. No significant financial relationships to disclose.

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Epidemiological Study of Lung Cancer Incidence in Lebanon

Medicina ◽

10.3390/medicina55060217 ◽

2019 ◽

Vol 55 (6) ◽

pp. 217 ◽

Cited By ~ 12

Author(s):

Hamza A. Salhab ◽

Mohamad Y. Fares ◽

Hussein H. Khachfe ◽

Hassan M. Khachfe

Keyword(s):

Lung Cancer ◽

Incidence Rate ◽

Cancer Incidence ◽

Incidence Rates ◽

Lung Cancer Incidence ◽

Cancer Incidence Rate ◽

Mena Region ◽

Mena Countries ◽

Common Cancer ◽

The World

Background and Objectives: Lung cancer (LC) is the most common cancer in the world. Developing countries in the Middle East and North Africa (MENA) region, including Lebanon, have witnessed a great increase in the incidence rates of this disease. The aim of our study is to investigate the incidence rates of lung cancer in Lebanon from 2005 to 2015 and to compare these rates to other countries from the MENA region and other regions of the world. Material and Methods: Lung cancer data for the years 2005–2015 were collected from the National Cancer Registry of Lebanon and stratified by gender and age group. Age-specific and age-standardized incidence rates were calculated and analyzed using joinpoint regression. Age-standardized incidence rates to the world population (ASR(w)) for other countries were obtained from two online databases. Results: Lung cancer ranked as the second most common cancer in Lebanon and accounted for 9.2% of all newly diagnosed cancers. Lung cancer ASR(w) showed a significantly increasing trend over the period studied for males and females. Lung cancer ASR(w) among males in Lebanon came second after Malta when compared to other MENA countries, but it was among the lowest when compared to non-MENA countries. For females, Lebanon ranked first when compared to other MENA countries but was among the lowest when compared to countries in other regions of the world. The lung cancer incidence rate increased with age in both sexes and 89.2% of patients were 50 years of age or older. Conclusion: Lebanon has the highest incidence of LC in females and the second highest for males in the MENA region. The lung cancer incidence rate is on the rise and older age groups are much more burdened by this disease than the young ones. Several risk factors, particularly smoking, play a role in increased LC incidence among the Lebanese population.

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Breast cancer incidence among women of Branicevo region in the period 1991 - 2000

Medicinski pregled ◽

10.2298/mpns0410467s ◽

2004 ◽

Vol 57 (9-10) ◽

pp. 467-472 ◽

Cited By ~ 2

Author(s):

Sandra Sipetic ◽

Vesna Petrovic ◽

Zorica Milic ◽

Hristina Vlajinac

Keyword(s):

Breast Cancer ◽

Incidence Rate ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Female Breast Cancer ◽

Incidence Rates ◽

Cancer Incidence Rate ◽

Breast Cancer Incidence Rate ◽

Female Breast ◽

The World

Introduction Breast cancer is the most common type of cancer in women, the second leading cause of cancer death, and the third most common cancer overall, throughout the world. In 1996, 910.000 new cases were diagnosed worldwide (about 9% of all new cases). Over 50% of breast cancer incidence occurred in the developed world. The aims of this study were to study breast cancer incidence during 1991-2000 in the region of Branicevo and to analyze differences in incidence rate for breast cancer in two periods of time 1991-1991 and 1996-2000. Material and methods This was a descriptive study. Routine national incidence data were used from the Republic Statistical Office. The analysis was restricted to the region of Branicevo. Age adjustment of annual incidence rates was carried out using five-year intervals and the distribution of the World population by Sega as the standard. Results A total of 542 women affected with breast cancer were evidenced in the Region of Branicevo during the period 1991- 2000, accounting for 25.3% of all malignant cases. Over the studied ten-year period the average standardized incidence rate (1:100,000) for breast cancer was 27.4. Based on the average age-specific incidence rates (1:100,000) female breast cancer was least frequently evidenced in women up to 34 years of age, while it was most frequent in groups aged 45 - 49 and 70 - 74 years. Over the period 1991-1995, female breast cancer accounted for 32.0% and in the period 1996-2000 for 22.2% of all mlignancies, with the average standardized incidence rates (1:100,000) being 22.5% and 32.4%, respectively. Discussion The average standardized incidence rate (1:100,000) for breast cancer was 27.4, which is similar to the rates evidenced in Eastern European countries, such as Poland (38.7), Slovakia (34.5), Hungary (29.6), Romania (31.1), Belarus (24.7) and Russia (40.6). Increase of breast cancer incidence rate, evidenced in the Region of Branicevo, is also evidenced in most countries with previously low incidence rates. Increase of breast cancer incidence rate is also detected in our neighboring countries, Bulgaria and Slovenia. Conclusions An increasing trend of breast cancer incidence rate was evidenced in the Region of Branicevo over the period 1991 - 2000, partially due to well kept registries and partially due to actual increase in the number of patients affected with malignant diseases.

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