Rat Studies on Quality of Protein and Growth-inhibiting Action of Alkaloids of Lupine (Lupinus termis)

1968 ◽  
Vol 94 (2) ◽  
pp. 161-165 ◽  
Author(s):  
R. I. Tannous ◽  
S. Shadarevian ◽  
J. W. Cowan
2018 ◽  
Vol 220 ◽  
pp. 69-73 ◽  
Author(s):  
Lidiya B. Vysotskaya ◽  
Tatyana N. Arkhipova ◽  
Guzel R. Kudoyarova ◽  
Stanislav Yu. Veselov

1950 ◽  
Vol 3 (1) ◽  
pp. 58-67 ◽  
Author(s):  
Camilla Wilske ◽  
Hans Burstrom

2018 ◽  
pp. 1-11
Author(s):  
Rama T. Rashad ◽  
Fatma H. A. El-Agyzy ◽  
Seham M. Abdel-Azeem

Aims: Two field experiments have been carried out to study the effect of different irrigation periods in the presence of compost as an organic amendment on the yield and quality of lupine (Lupinus termis L.) under the sandy soil conditions. Study Design: Split-plot design.  Place and Duration of Study: The successive winter seasons of 2016/2017 and 2017/2018 at the Ismailia Agricultural Research Station, (30°35'30" N 32°14'50" E elevation 3 m), Agricultural Research Center (ARC), Egypt. Methodology: Compost has been applied at the rates of 11.90, 23.81 and 35.71 ton/ha before planting. Three irrigation intervals were assigned after planting by 3, 6, and 9 days; the applied water volume for each was 4761.91 m3/ha. Results: After harvesting, some parameters were estimated. As the compost rates increased, the soil EC significantly decreased while the available N, P, K, and Fe were significantly increased by 9.51, 12.79, 5.17, and 5.8%, respectively. For same compost rate, the irrigation intervals (3, 6, and 9 days) significantly decreased the available N relatively by 2.88, 5.16, and 6.96%, respectively and the available K by 3.45, 5.06, and 4.37%, respectively. The 6 days interval showed that most significant increase in the seeds' content of nutrients at different compost rates and the seed yield has increased by 19.59, 22.31, and 21.88% for the compost rates of 11.90, 23.81, and 35.71 ton/ha, respectively. The relative increase was by 20.48, 7.63, 4.49, 10.89, and 14.92% for the crude protein, crude lipids, total ash, TSS and the amino acids, respectively. The effect of treatments on the relative shoot moisture (%) and the field water use efficiency (F.W.U.E.) (kg/m3) was discussed. Conclusion: The 6 days irrigation interval along with a compost application rate of 23.81 ton/ha can be recommended for lupine grown in sandy soil as they showed the most significant increase in the nutrients content of seeds by 22.31%.


1951 ◽  
Vol 93 (1) ◽  
pp. 13-24 ◽  
Author(s):  
D. W. Woolley ◽  

In a series of 26 species selected from widely differing classes, 1,2-dichloro-4,5-diaminobenzene was toxic to those which did not exhibit a nutritional need for riboflavin plus vitamin B12. It failed to retard the growth of those which needed both of these vitamins. The compound was conceived as an antimetabolite of 1,2-dimethyl-4,5-diaminobenzene. This latter, which is contained within the structures of the two vitamins, was pictured as a metabolic precursor of them. It was found to have very slight activity as either riboflavin or as vitamin B12 for lactic acid bacteria and algae. The growth-inhibiting action of the dichlorodiaminobenzene was overcome competitively by the dimethyidiaminobenzene, and also, to a lesser extent, by o-phenylenediamine. The toxicity was not influenced by additions of riboflavin plus vitamin B12, except in the cases of two species, where the influence was slight. These facts were considered to support the idea that properly constructed analogs of a precursor of two or more essential participants in cell division may be able to circumvent the counteraction which the vitamin has been found to exert on an antimetabolite of its precursor. Alternate explanations of the observed data were likewise considered.


1923 ◽  
Vol 37 (5) ◽  
pp. 653-658 ◽  
Author(s):  
Alexis Carrel ◽  
Albert H. Ebeling

The substances precipitated by CO2 from the serum of chickens 1 or 2 years old slightly increased the activity of pure cultures of a 10 year old strain of fibroblasts, an indication that a growth-promoting substance had been obtained from the serum. The rate of growth of fibroblasts was slower in serum deprived of its globulins and the increase of the inhibiting effect of the treated serum is thus manifested. It would appear that the inhibiting action of serum is referable to one or several growth-activating substances which precipitate by CO2, and to one or several growth-retarding substances which remain in the supernatant serum after the precipitate has been thrown down by centrifugation. It may be concluded that, under the conditions of the experiments: 1. A substance enhancing the proliferative activity of homologous fibroblasts is precipitated from serum by CO2. 2. The serum from which the precipitate has been removed inhibits the proliferation of homologous fibroblasts more markedly than does the original serum. The solution of the precipitate in the treated serum has about the same effect on fibroblasts as the original serum. 3. The restraining effect of serum on the activity of homologous fibroblasts is due in part to the antagonistic action of growth-activating and inhibiting substances.


1925 ◽  
Vol 42 (2) ◽  
pp. 143-154 ◽  
Author(s):  
Lillian E. Baker ◽  
Alexis Carrel

The growth-inhibiting action of serum has been shown to be due largely to the lipoids. Serum from which the lipoids have been removed is much less inhibiting to the growth of fibroblasts in vitro than is the original serum, and only slightly more inhibiting than Tyrode solution. The lipoids extracted from the serum are toxic and more inhibiting to the growth of fibroblasts than the original serum. Lipoids extracted from chicken brain, chicken liver, egg, and embryonic tissue have likewise an inhibiting action.


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