scholarly journals Stat Bite: Incidence of and Mortality From Oral Cavity and Pharynx Cancer, 1975–2002

2006 ◽  
Vol 98 (2) ◽  
pp. 87-87
Keyword(s):  
2011 ◽  
pp. 191-198
Author(s):  
Michelle E Denison ◽  
Libia Soto ◽  
Carlos Alfonso Reyes-Ortiz

Objective: The objective of this study was to explore the association between aging of population and incidence of oral cavity and pharynx cancer at the country level in the American continent. Methods: An ecological study at the country level. Countries’ data for oral cavity and pharynx cancer incidence comes from the International Agency for Cancer Research (GLOBOCAN 2002). Twenty eight countries were included from North America, Central America, and South America. The dependent variables were the countries’ oral cavity and pharynx cancer incidence rates (per 100,000/ year) by sex, overall and age-specific groups, 0-64 (younger population) and 65+ (older population), and the main independent variable was the countries’ aging population (% of persons 65 years and older). Other variables considered were per-capita gross national income and prevalence of smoking by sex at the country level. Results: Overall countries’ level of oral cavity and pharynx cancer incidence rates were strongly correlated with the countries’ aging population (p<0.01). In adjusted regression analyses, the countries’ aging population was significantly associated with overall oral cavity and pharynx cancer incidence rates for male (p<0.0001, p=0.0003) and female (p=0.0025, p=0.0134) populations. Conclusion: Countries’ aging population was associated with increased countries’ oral cavity and pharynx cancer incidence rates in the American continent.


2015 ◽  
Vol 80 (6) ◽  
pp. 38
Author(s):  
E. L. Choinzonov ◽  
L. F. Pisareva ◽  
I. N. Odintsova ◽  
L. D. Zhuikova
Keyword(s):  
Far East ◽  

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 6045-6045 ◽  
Author(s):  
Siddharth Sheth ◽  
Doug Farquhar ◽  
Angela Mazul ◽  
David N. Hayes ◽  
Jose Zevallos ◽  
...  

6045 Background: Growing literature suggests that racial disparities exist in patients with head and neck squamous cell carcinoma (HNSCC). Currently, there are many hospital-based cohorts assessing racial disparities, however only a limited number of population-based cohorts exist. This study aims to explore the association between clinical characteristics and patient demographics with overall survival by race and HPV status. Methods: Patients were identified from the Carolina Head and Neck Cancer Study (CHANCE), a population based case-control study with enrollment from 2001-2006 in North Carolina. Vital status was determined by linkage with the National Death Index. Survival was considered at 5 years after diagnosis or study enrollment. We used Kaplan-Meyer analyses and Cox proportional hazards regression modeling to estimate adjusted hazard ratios (HR) and 95% confidence intervals (CI). Results: A total of 1361 HNSCC patients with no baseline metastasis and adequate survival time were identified. Of these, 1010 patients were white while 351 patients were black. Black patients were statistically more likely to be younger at age of diagnosis, have a history of tobacco or alcohol use, be uninsured, and not have completed high school (p-value < 0.001). In an unadjusted cox regression analysis, blacks had 1.50 times (95% CI 1.01-1.57) decreased overall survival than whites. Adjusting for gender, stage of disease, age, treatment, and smoking status, this relationship remained (HR 1.30, CI 1.1-1.6). In a subset analysis of male patients by disease site, there was decreased overall survival in black patients in oral cavity cases (p < 0.01). This relationship trended towards significant in pharynx cancer (p = 0.054) and was not found in laryngeal cancer. In pharyngeal cases only, there was decreased overall survival in black patients with HPV+ disease (p = 0.03) but not in HPV- cases (p = 0.33). Conclusions: This is the first population-based study that confirms racial disparities in HPV+ HNSCC. We also found worse overall survival prognosis for black patients with oral cavity cancer and a similar trend in pharynx cancer. Further studies are needed to evaluate if this difference is driven by either biological or socioeconomic factors.


2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Linda Morris Brown ◽  
David P. Check ◽  
Susan S. Devesa

Objective. To evaluate oral cavity and pharynx cancer (OCPC) patterns by gender.Methods. We used Surveillance, Epidemiology, and End Results program data for 71,446 cases diagnosed during 1975–2008 to classify OCPC by anatomic subsite as potentially HPV-related or not, with oral tongue cancer considered a separate category.Results. Total OCPC rates among men were 2–4 times those among women. Among whites, total OCPC rates rose in the younger age groups due to substantial increases in successive birth cohorts for HPV-related cancers, more rapid among men than women, and oral tongue cancers, more rapid among women than men. Among blacks, total OCPC rates declined among cohorts born since 1930 reflecting the strong downward trends for HPV-unrelated sites. Among Hispanics and Asians, HPV-unrelated cancer rates generally declined, and oral tongue cancer rates appeared to be converging among young men and women.Conclusions. Decreases in total OCPC incidence reflect reductions in smoking and alcohol drinking. Rising HPV-related cancers among white men may reflect changing sexual practices. Reasons for the increasing young oral tongue cancer rates are unknown, but the narrowing of the gender differences provides a clue.


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