scholarly journals An occult case of the first branchial cleft anomaly

2020 ◽  
Vol 2020 (9) ◽  
Author(s):  
Yumi Muranishi ◽  
Soh Nishimoto ◽  
Kenichiro Kawai ◽  
Hisako Ishise ◽  
Masao Kakibuchi

Abstract We report a case of the first branchial cleft anomaly, clinically typical but occult in images and pathology. An 8-year-old female who had an induration below her right mandibular angle was referred to our department with a diagnosis of an infectious epidermal cyst. CT and MRI had shown no evidence of fistula or cyst. At the initial operation, a string structure was observed, but pathologically no epithelial structure was observed. However, the infection at the same site repeated and the symptoms became more severe than before. Considering a high probability of the first branchial anomaly, partial parotidectomy was performed as radical surgery. A cord structure attached to subcutaneous tissue at the intertragal notch was found. Although no epithelial component in the pathology was detected, this string structure was clinically considered as the rudimentary form of the first branchial anomaly.

2020 ◽  
pp. 1-3
Author(s):  
Seung Won Park ◽  
Jong Han Gill ◽  
Myeong Jin Ko ◽  
Seong Hyun Wui ◽  
Seung Won Park

An intramuscular epidermal cyst without subcutaneous involvement is extremely rare. The patient presented with low back pain. Spinal magnetic resonance imaging indicated spindle-shaped mass in the right erector spinae muscles located at L3 to L5 level without any connection with subcutaneous tissue. The patient underwent operation for removal of intramuscular cystic lesion. The tumor was totally removed and pathologically confirmed with epidermal cyst. Unlike typical epidermal cyst, the patient had a characteristic clinical manifestation of mild low back pain without palpable mass and local tenderness.


2021 ◽  
Vol 26 (1) ◽  
pp. 47-52
Author(s):  
Erkan Gökçe ◽  
Murat Beyhan

2011 ◽  
Vol 19 (1-2) ◽  
pp. 17-22
Author(s):  
Valentina Krstevska ◽  
Igor Stojkovski ◽  
Emilija Lazarevska ◽  
Simonida Crvenkova

Background: The aim of this study is to analyze the results of radical surgery followed by postoperative radiotherapy in patients with advanced laryngeal cancer. Methods: Seventy-seven patients with advanced laryngeal cancer were treated with postoperative radiotherapy following total laryngectomy with or without neck dissection. Median age of patients at the diagnosis was 57 years (range, 43-76). The median follow-up was 41 months (range, 11-70). Radiotherapy was performed using three-dimensional conformal technique. Results: Median duration of overall radiation treatment time was 5.9 weeks (range, 5.4-7.6). Median total dose delivered was 60 Gy (range, 50-66). Locoregional relapse was the most frequent pattern of failure. A 5-year locoregional control (LRC) and overall survival (OS) rates were 72.3% and 66.2%, respectively. A 5-year LRC and OS rates were significantly higher in patients without nodal disease (N0) as compared to patients with metastatic involvement of the neck lymph nodes (N+) (p=0.009 and p=0.002, respectively). Confluent mucositis was developed in 16 patients (20.8%). Late toxicity most frequently occurred in the skin as well as in the mucous membrane and in the subcutaneous tissue and was grade 1 reaction (74.0%, 67.5%, and 72.7%, respectively). Conclusion: In order to improve treatment results in terms of LRC and OS and following evidence-based treatment recommendations for patients with advanced laryngeal cancer whose initial treatment was radical surgery, we strongly advocate the acceptance of postoperative concurrent chemoradiotherapy in cases with surgical specimen demonstrating high-risk pathological features.


2001 ◽  
Vol 46 (3) ◽  
pp. 350-351
Author(s):  
Yavuz Demir ◽  
Seyhan ??eneto??lu ◽  
Nalan Aky??rek ◽  
Reha Yavuzer

2021 ◽  
Vol 13 (2) ◽  
Author(s):  
Tomoka Harada ◽  
Takeshi Fukumoto ◽  
Hideki Shimizu ◽  
Chikako Nishigori

Cutaneous epidermal cysts are common benign cysts derived from the epidermis or epithelium of hair follicles, and malignancy originating from epidermal cysts is uncommon. When a cutaneous epidermal cyst turns malignant, it is mostly squamous cell carcinoma, and basal cell carcinoma is rare. We present the case of a 58-year-old man with basal cell carcinoma originating from an epidermal cyst on the buttocks. Histopathological analysis with hematoxylin- eosin (H&E) staining showed the presence of the cyst, the wall of which was partially replaced by a malignant tumor. Moreover, the cyst was filled with malignant tumor cells in some areas. The tumor cells were basaloid, and extended through the dermis down to the subcutaneous tissue in a solid pattern. Immunoperoxidase staining for Ber-EP4 was positive. To our knowledge, there are 11 reported cases of BCC originating from epidermal cysts in English, and we reviewed these reports and examined potential trends. We estimate that some longstanding epidermal cysts may have the potential of malignant transformation, and chronic and repeated irritation might trigger malignancy from epidermal cysts. We emphasize that benignlooking cystic lesions showing progressive growth should be examined histopathologically.


Author(s):  
P. J. Melnick ◽  
J. W. Cha ◽  
E. Samouhos

Spontaneous mammary tumors in females of a high tumor strain of C3H mice were cut into small fragments that were Implanted into the subcutaneous tissue of the back of males of the same strain, where they grew as transplantable tumors. When about Cm. In diameter daily fractional radiation was begun, applied to the tumors, the rest of the body being shielded by a lead shield. Two groups were treated with 150 and 200 r X-ray dally, of half value layer 0.6mm. copper; a third group was treated with 500 r cobalt radiation dally. The primary purpose was to examine the enzyme changes during radiation, with histochemlcal technics.


VASA ◽  
2011 ◽  
Vol 40 (4) ◽  
pp. 271-279 ◽  
Author(s):  
Wagner

Lymphedema and lipedema are chronic progressive disorders for which no causal therapy exists so far. Many general practitioners will rarely see these disorders with the consequence that diagnosis is often delayed. The pathophysiological basis is edematization of the tissues. Lymphedema involves an impairment of lymph drainage with resultant fluid build-up. Lipedema arises from an orthostatic predisposition to edema in pathologically increased subcutaneous tissue. Treatment includes complex physical decongestion by manual lymph drainage and absolutely uncompromising compression therapy whether it is by bandage in the intensive phase to reduce edema or with a flat knit compression stocking to maintain volume.


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