Soft Tissue

The integumentary system is formed from the mesoderm. Skin and its appendages compose the largest bodily organ. The integumentary system and underlying soft tissue (fat, fascia, and muscle) protect the body from damage and infection. Skin lesions are typically asymptomatic, but they occasionally itch, bleed, or ulcerate. Work-up for diagnosis of soft tissue sarcomas includes CT, MRI, and biopsy. First-line treatment for symptomatic benign lipomas is surgical resection. Complications of surgical treatment of malignant tumors of the skin and soft tissue are postoperative bleeding, infection, hematoma, and recurrence.

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Adriamycin and Cis-Platinum as First-Line Treatment in Unresectable Locally Advanced or Metastatic Adult Soft-Tissue Sarcomas

American Journal of Clinical Oncology ◽

10.1097/01.coc.0000071467.96942.2f ◽

2004 ◽

Vol 27 (3) ◽

pp. 307-311 ◽

Cited By ~ 1

Author(s):

Haralabos P. Kalofonos ◽

Dimitrios Bafaloukos ◽

Theodoros G. Kourelis ◽

Michalis V. Karamouzis ◽

Panagiotis Megas ◽

...

Keyword(s):

Soft Tissue ◽

Locally Advanced ◽

Soft Tissue Sarcomas ◽

Line Treatment ◽

First Line ◽

First Line Treatment

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Randomized, Open, Prospective, Phase II Clinical Trial of Doxorubicin (DOXO) vs. Trabectedin Plus Doxo in the First-Line Treatment of Patients (PTS) with Advanced Non-Operable and/or Metastatic Soft Tissue Sarcomas (STS): Geis-20 Study

Annals of Oncology ◽

10.1016/s0923-7534(20)34065-5 ◽

2012 ◽

Vol 23 ◽

pp. ix490 ◽

Cited By ~ 1

Author(s):

J. Martin Broto ◽

X. Garcia Del Muro ◽

A. Lopez-Pousa ◽

R. Las De Penas ◽

J. Maurel ◽

...

Keyword(s):

Clinical Trial ◽

Soft Tissue ◽

Phase Ii ◽

Soft Tissue Sarcomas ◽

Phase Ii Clinical Trial ◽

Line Treatment ◽

First Line ◽

Prospective Phase ◽

First Line Treatment

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Clinicopathological study of soft tissue sarcoma-retrospective study of tertiary cancer institute in eastern India

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20204907 ◽

2020 ◽

Vol 8 (11) ◽

pp. 4075

Author(s):

Kunhi Mohammed K. P. ◽

Snehasis Pradhan ◽

Supratim Bhattacharyya ◽

Prafulla Kumar Das ◽

Muhammed Navas N. K.

Keyword(s):

Retrospective Study ◽

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Malignant Tumors ◽

Soft Tissue Sarcomas ◽

The Body ◽

Female Ratio ◽

Pleomorphic Sarcoma ◽

Frequent Variety ◽

Male To Female

Background: Soft tissue sarcomas are a rare and heterogeneous group of malignant tumors of mesenchymal origin that comprise less than 1 percent of all adult malignancies. Although they occur anywhere in the body, they involve most commonly in extremities, trunk, retroperitoneum and head and neck. The aim of the study was to analyze clinical and histopathological features of various soft tissue sarcomas.Methods: This was a retrospective study, conducted in tertiary cancer centre in Odisha during the period 2015 to 2018. We collected clinical parameters like age, sex, site of swelling, any associated pain and biopsy reports and these variables were correlated with final histopathology reports.Results: A total of 107 patients were included in the study, with male to female ratio of 2:1(71 and 36) and average age of 43.45 years. All of them presented with a swelling. The lower extremities were the most common sites i.e. 44.62%. Pleomorphic sarcoma was the most frequent histologic variety comprising 43% and less frequent variety were angiosarcoma, and myxoid sarcoma.Conclusions: Soft tissue sarcoma are predominant in males and middle aged population are frequently affected. Most common affected site is lower extremity and pleomorphic sarcoma is the prominent histologic type.

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