scholarly journals Concussion One Hour Later

Concussion ◽  
2019 ◽  
pp. 45-48
Author(s):  
Brian Hainline ◽  
Lindsey J. Gurin ◽  
Daniel M. Torres
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Brain Imaging ◽  
Brain Damage ◽  
Severe Traumatic Brain Injury ◽  
Metabolic Dysfunction ◽  
Singular Event ◽  
Initial Injury ◽  
The Individual ◽  
Over Time

Concussion is not a singular event, but rather a neurological process that may evolve over minutes to hours. Individuals with uncomplicated concussion may develop either increased or new symptoms during the first several hours following the initial injury, yet such symptoms do not result from progressive brain damage but rather a functional cascade of metabolic dysfunction. Any individual with suspected concussion should be monitored serially, as symptoms may evolve over time. When worsening symptoms do not manifest with worrisome neurologic signs, the individual does not require urgent transfer to a hospital and does not need urgent brain imaging studies. Therefore, concussion symptom evolution should be anticipated and distinguished from more severe traumatic brain injury.

CHANGES IN THE OUTCOME OF PEDIATRIC PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY OVER TIME

2004 ◽  
Vol 32 (Supplement) ◽  
pp. A101
Author(s):  
Kelly S Tieves ◽  
Cheryl A Muszynski ◽  
Bruce A Kaufman ◽  
Peter L Havens ◽  
Jayesh C Thakker
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Pediatric Patients ◽  
Over Time

Polymorphism of the APOE Gene and Markers of Brain Damage in the Outcomes of Severe Traumatic Brain Injury in Children

2020 ◽  
Vol 51 (1) ◽  
pp. 28-35
Author(s):  
E. G. Sorokina ◽  
Zh. B. Semenova ◽  
N. S. Averianova ◽  
O. V. Karaseva ◽  
E. N. Arsenieva ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Brain Damage ◽  
Severe Traumatic Brain Injury ◽  
Apoe Gene

APOΕ gene polymorphism and markers of brain damage in the outcomes of severe traumatic brain injury in children

2020 ◽  
Vol 120 (4) ◽  
pp. 72
Author(s):  
E.G. Sorokina ◽  
Zh.B. Semenova ◽  
N.S. Averianova ◽  
O.V. Karaseva ◽  
E. N Arsenieva ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Gene Polymorphism ◽  
Brain Damage ◽  
Severe Traumatic Brain Injury

scholarly journals The radiological interpretation of possible microbleeds after moderate or severe traumatic brain injury: a longitudinal study

2021 ◽  
Author(s):  
Anke W. van der Eerden ◽  
Thomas L. A. van den Heuvel ◽  
Marnix C. Maas ◽  
Priya Vart ◽  
Pieter E. Vos ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Longitudinal Study ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Time Points ◽  
Computer Aided ◽  
Clinical Consequences ◽  
Severe Tbi ◽  
Over Time

Abstract Introduction In order to augment the certainty of the radiological interpretation of “possible microbleeds” after traumatic brain injury (TBI), we assessed their longitudinal evolution on 3-T SWI in patients with moderate/severe TBI. Methods Standardized 3-T SWI and T1-weighted imaging were obtained 3 and 26 weeks after TBI in 31 patients. Their microbleeds were computer-aided detected and classified by a neuroradiologist as no, possible, or definite at baseline and follow-up, separately (single-scan evaluation). Thereafter, the classifications were re-evaluated after comparison between the time-points (post-comparison evaluation). We selected the possible microbleeds at baseline at single-scan evaluation and recorded their post-comparison classification at follow-up. Results Of the 1038 microbleeds at baseline, 173 were possible microbleeds. Of these, 53.8% corresponded to no microbleed at follow-up. At follow-up, 30.6% were possible and 15.6% were definite. Of the 120 differences between baseline and follow-up, 10% showed evidence of a pathophysiological change over time. Proximity to extra-axial injury and proximity to definite microbleeds were independently predictive of becoming a definite microbleed at follow-up. The reclassification level differed between anatomical locations. Conclusions Our findings support disregarding possible microbleeds in the absence of clinical consequences. In selected cases, however, a follow-up SWI-scan could be considered to exclude evolution into a definite microbleed.

scholarly journals Features of the Clinical Course and Prognosis of Severe Traumatic Brain Injury Outcomes

2020 ◽  
Vol 8 (4) ◽  
pp. 423-429
Author(s):  
Y. B. Vasilyeva ◽  
A. E. Talypov ◽  
M. V. Sinkin ◽  
S. S. Petrikov
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Brain Damage ◽  
Clinical Course ◽  
Neurological Status ◽  
Diagnostic Methods ◽  
The World ◽  
Different Types ◽  
The Brain ◽  
Over Time

BACKGROUND. Traumatic brain injury (TBI) is one of the most important contemporary health issues. According to the World Health Organization, TBI is one of three leading causes of death in the world. Despite the development and widespread use of neuroimaging tools and instrumental research methods, clinical diagnosis of TBI is preferred. It is especially relevant at the prehospital stage when it is impossible to use instrumental diagnostic methods.THE AIM OF THE STUDY. To determine the clinical course features and prognosis of treatment outcomes in patients with various types of traumatic brain damage.MATERIAL AND METHODS. We studied the results of examination and treatment of 100 victims with a severe head injury hospitalized during the first days after receiving an injury and undergoing treatment at the N.V. Sklifosovsky Research Institute in 2008–2017. Depending on the type of brain injury patients were divided into 3 groups: Group 1 — isolated hematoma (n=20), Group 2 — hematomas and injuries of the brain (n=40), Group 3 — injuries of the brain (n=40). All patients underwent neurological examination, CT scan of the brain upon admission and over time within 12 days after trauma. In 30 victims, intracranial pressure (ICP) was monitored.RESULTS. We revealed features of the dynamics of individual neurological symptoms in patients with different types of brain damage. In patients with isolated hematomas, neurological status was represented mainly with clinic dislocation syndrome and contralateral hematoma hemiparesis, and clinical pattern significantly depended on intracranial hemorrhage. In patients with combination of hematomas and contusions, the neurological status and its dynamics were less dependent on the volume of the hematoma and were mainly determined by contusions of the midline structures of the brain. In patients with brain injuries, neurological status reliably correlated with injuries of midline structures.CONCLUSION. We revealed significant differences in neurological status, its changes over time and correlation with CT findings in patients with different types of traumatic brain injury.Authors declare lack of the conflicts of interests.

Changes in Therapeutic Intensity Level Following Airway Pressure Release Ventilation in Severe Traumatic Brain Injury

2016 ◽  
Vol 33 (3) ◽  
pp. 196-202 ◽  
Author(s):  
Jeffrey J. Fletcher ◽  
Thomas J. Wilson ◽  
Venkatakrishna Rajajee ◽  
Scott B. Davidson ◽  
Jon C. Walsh
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Airway Pressure ◽  
Intensity Level ◽  
Static Compliance ◽  
Pressure Release ◽  
Therapeutic Intensity ◽  
Pressure Release Ventilation ◽  
Over Time

Purpose: Airway pressure release ventilation (APRV) utilizes high levels of airway pressure coupled with brief expiratory release to facilitate open lung ventilation. The aim of our study was to evaluate the effects of APRV-induced elevated airway pressure mean in patients with severe traumatic brain injury. Materials and Methods: This was a retrospective cohort study at a 424-bed Level I trauma center. Linear mixed effects models were developed to assess the difference in therapeutic intensity level (TIL), intracranial pressure (ICP), and cerebral perfusion pressure (CPP) over time following the application of APRV. Results: The study included 21 epochs of APRV in 21 patients. In the 6-hour epoch following the application of APRV, the TIL was significantly increased ( P = .002) and the ICP significantly decreased ( P = .041) compared to that before 6 hours. There was no significant change in CPP ( P = .42) over time. The baseline static compliance and time interaction was not significant for TIL (χ2 = 0.2 [ df 1], P = .655), CPP (χ2 = 0 [ df 1], P = 1), or ICP (χ2 = 0.1 [ df 1], P = .752). Conclusions: Application of APRV in patients with severe traumatic brain injury was associated with significantly, but not clinically meaningful, increased TIL and decreased ICP. No significant change in CPP was observed. No difference was observed based on the baseline pulmonary static compliance.

Changes in the Outcome of Pediatric Patients with Severe Traumatic Brain Injury over Time

2005 ◽  
Vol 6 (1) ◽  
pp. 116
Author(s):  
K S Tieves ◽  
C A Muszynski ◽  
B A Kaufman ◽  
J C Thakker ◽  
P L Havens
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Pediatric Patients ◽  
Over Time
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