Leprosy (Hansen’s disease)

2020 ◽  
pp. 1154-1167
Author(s):  
Diana N.J. Lockwood

Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae, an acid-fast intracellular organism not yet cultivated in vitro. It is an important public health problem worldwide, with an estimated 4 million people disabled by the disease. Transmission of M. leprae is only partially understood, but untreated lepromatous patients discharge abundant organisms from their nasal mucosa into the environment. It was first identified in the nodules of patients with lepromatous leprosy by Hansen in 1873. M. leprae preferentially parasitizes skin macrophages and peripheral nerve Schwann cells. A second agent of leprosy M. lepromatosis which diverged form M. leprae 10 million years ago has also been recognized as causing leprosy in 40 + patients and the main focus of origin is Mexico. The importance of this organism will be determined over the next few years.

Author(s):  
Diana N.J. Lockwood

Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae, an acid-fast intracellular organism not yet cultivated in vitro. It is an important public health problem worldwide, with an estimated 4 million people disabled by the disease. Transmission of M. leprae is only partially understood, but untreated lepromatous patients discharge abundant organisms from their nasal mucosa into the environment....


PEDIATRICS ◽  
1964 ◽  
Vol 34 (1) ◽  
pp. 32-37
Author(s):  
Dacio Pinheiro

Tetanus in the newborn infant is still a most important public health problem in Brazil. An analysis of 238 cases, admitted in a two-year period to the pediatric service of the University Hospital in Sao Paulo, is presented. It is suggested that prognosis is related more closely to amount of tetanospasmin produced and absorbed by the central nervous system than to some of the more traditional indices of clinical severity. The plan of treatment in use is presented, since the over-all recovery rate compares very favorably with other published reports.


Author(s):  
Jose Andonegui ◽  
Aitor Eguzkiza ◽  
Mikel Auzmendi ◽  
Luis Serrano ◽  
Ane Zurutuza ◽  
...  

e-Ophthalmology is the use of information and telecommunications technologies to provide or support a group of activities related to ophthalmic care. Chronic glaucoma is an ocular disease characterized by optic neuropathy that leads to progressive loss of the visual fields and often is associated with elevated intraocular pressure levels. Glaucoma is an important public health problem because it is one of the main causes of blindness worldwide and generates an important demand for ophthalmologic consultations. The aim of this chapter is to discuss the application e-Ophthalmology-based models in the diagnosis and follow-up of chronic glaucoma. The authors describe the current status of the use of e-Ophthalmology-based models in the screening and follow-up of chronic glaucoma, the main advantages of these models, the technologic requirements for their implementation, and future trends in this field.


2018 ◽  
Vol 28 ◽  
Author(s):  
Marcio Roberto Silva ◽  
André Almeida Santos Duch ◽  
Rômulo Tadeu Pace de Assis Lage ◽  
Liliane Denize Miranda Menezes ◽  
João Batista Ribeiro ◽  
...  

2012 ◽  
Vol 22 (3) ◽  
pp. 422-424 ◽  
Author(s):  
G. van Schoor ◽  
J. D. M. Otten ◽  
G. J. den Heeten ◽  
R. Holland ◽  
M. J. M. Broeders ◽  
...  

2018 ◽  
Vol 73 ◽  
pp. 316-317
Author(s):  
R. Colebunders ◽  
A. Hotterbeekx ◽  
J. Siewe ◽  
M. Mandro ◽  
M. Mbonye ◽  
...  

AAOHN Journal ◽  
2009 ◽  
Vol 57 (10) ◽  
pp. 436-436
Author(s):  
Olga S. Tompkins

Noise pollution can cause nonauditory effects on general health and well-being. There is growing awareness that secondhand noise is an important public health problem that is similar in scope to secondhand smoke.


2007 ◽  
Vol 12 (11) ◽  
Author(s):  
T Baranovich ◽  
V Potapov ◽  
T Yamamoto

Since the first report of pediatric deaths in 1997-1999 in the United States, community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has become an increasingly important public health problem worldwide.


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