Nursing patients with neurological problems

Nursing assessment of patients with neurological problems 436 Physical examination 438 Diagnostic tests 442 Neurological nursing problems 446 Epilepsy/seizure 448 Paralysis 450 Meningitis 452 Encephalitis 454 Chronic neurological conditions 456 Multiple sclerosis 458 Parkinson’s disease 460 Degenerative diseases 462 Stroke and transient ischaemic attack (TIA): overview ...

Multiple sclerosis, Motor neurone disease, Parkinson’s disease, Alzheimer’s disease, Ketogenic therapy for epilepsy


Neuro-Urology ◽  
2018 ◽  
pp. 55-79 ◽  
Author(s):  
Petros Georgopoulos ◽  
Konstantinos-Vaios Mytilekas ◽  
Apostolos Apostolidis

2021 ◽  
Vol 27 ◽  
Author(s):  
Niklas Frahm ◽  
Michael Hecker ◽  
Uwe Zettl

: Polypharmacy is an important aspect of medication management and particularly affects elderly and chronically ill people. Patients with dementia, Parkinson’s disease (PD) or multiple sclerosis (MS) are at high risk for multimedication due to their complex symptomatology. Our aim was to provide an overview of different definitions of polypharmacy and to present the current state of research on polypharmacy in patients with dementia, PD or MS. The most common definition of polypharmacy in the literature is the concomitant use of ≥5 medications (quantitative definition approach). Polypharmacy rates of up to >50% have been reported for patients with dementia, PD or MS, although MS patients are on average significantly younger than those with dementia or PD. The main predictor of polypharmacy is the complex symptom profile of these neurological disorders. Potentially inappropriate medication (PIM), drug-drug interactions, poor treatment adherence, severe disease course, cognitive impairment, hospitalisation, poor quality of life, frailty and mortality have been associated with polypharmacy in patients with dementia, PD or MS. For patients with polypharmacy, either the avoidance of PIM (selective deprescribing) or the substitution of PIM with more suitable drugs (appropriate polypharmacy) is recommended to achieve a more effective therapeutic management.


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