Assessment of liver function

Author(s):  
Daniel Marks ◽  
Marcus Harbord

Interpretation of liver function tests Imaging Liver biopsy The patient with persistently deranged liver function tests but normal investigations Liver function tests (LFT) can be divided into markers of hepatocyte or biliary epithelial cell integrity (ALT, AST, ALP, γ‎GT), and those indicative of synthetic/metabolic function (albumin, INR/PTT, bilirubin, ammonia). In addition, hypoglycaemia, lactic acidosis, and elevated lactate dehydrogenase (LDH) can be non-specific markers of severe hepatic dysfunction....

1977 ◽  
Vol 23 (4) ◽  
pp. 627-630 ◽  
Author(s):  
Paul Phillip Sher

Abstract I evaluated the diagnostic value of routinely ordered liver-function tests in 175 biopsy-proven cases of hepatic disease by use of stepwise discriminant analysis. The tests studied—total and "direct" bilirubin, alkaline phosphatase, lactate dehydrogenase, and aspartate aminotrans-ferase—correctly classified 45-73% of cases, depending on the homogeneity of the diagnostic groups. Aspartate aminotransferase and alkaline phosphatase were the best discriminators. When all tests were used in the most ho-mogeneous groups (tumors, cirrhosis, and hepatitis), there was a stepwise improvement in diagnostic accuracy from 51 to 73%.


2014 ◽  
Vol 52 (08) ◽  
Author(s):  
KC Grotemeyer ◽  
H Wilkens ◽  
F Lammert ◽  
R Bals ◽  
R Kaiser

Endoscopy ◽  
2006 ◽  
Vol 38 (11) ◽  
Author(s):  
BJ Egan ◽  
S Sarwar ◽  
M Anwar ◽  
C O'Morain ◽  
B Ryan

2011 ◽  
Vol 3 (10) ◽  
pp. 1-3 ◽  
Author(s):  
Dr. Amit P Trivedi ◽  
◽  
Dr. Kiran P Chauhan ◽  
Dr. N Haridas Dr. N Haridas

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