Oesophageal cancer

Worldwide, oesophageal cancer, including cancer of the gastro-oesophageal junction (GEJ), is the sixth leading cause of death from cancer. Despite recent advances, treatment of oesophageal cancer remains challenging and is best approached by an experienced multidisciplinary team. Surgery alone is the treatment of choice in early stage carcinoma although in superficial cancers (T1a) endoscopic resection is to be preferred. In locally advanced tumors induction therapy followed by surgery is the preferred treatment. In selected cases definitive chemoradiotherapy could be considered as a valuable alternative The role of adjuvant chemotherapy is unclear, but could be considered for selected GEJ adenocarcinoma patients. Adjuvant chemoradiotherapy should be considered in all patients with advanced disease or positive margins who did not receive neo-adjuvant radiotherapy. For metastatic disease, the goal is to prolong and maximize quality of life. Regarding the palliative treatment of dysphagia, brachytherapy was shown to be more effective than stenting.

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Oesophageal cancer

Oxford Textbook of Oncology ◽

10.1093/med/9780199656103.003.0036_update_002 ◽

2016 ◽

pp. 365-387

Author(s):

Melissa Thomas ◽

Karin Haustermans ◽

Eric Van Cutsem ◽

Piet Dirix ◽

Xavier Sagaert ◽

...

Keyword(s):

Oesophageal Cancer ◽

Adjuvant Radiotherapy ◽

Palliative Treatment ◽

Early Stage ◽

Locally Advanced ◽

Adjuvant Chemoradiotherapy ◽

Valuable Alternative ◽

Early Stage Carcinoma

Worldwide, oesophageal cancer, including cancer of the gastro-oesophageal junction (GEJ), is the sixth leading cause of death from cancer. Despite recent advances, treatment of oesophageal cancer remains challenging and is best approached by an experienced multidisciplinary team. Surgery alone is the treatment of choice in early stage carcinoma although in superficial cancers (T1a) endoscopic resection is to be preferred. In locally advanced tumours induction therapy followed by surgery is the preferred treatment. In selected cases definitive chemoradiotherapy could be considered as a valuable alternative. The role of adjuvant chemotherapy is unclear, but could be considered for selected GEJ adenocarcinoma patients. Adjuvant chemoradiotherapy should be considered in all patients with advanced disease or positive margins who did not receive neo-adjuvant radiotherapy. For metastatic disease, the goal is to prolong and maximize quality of life. Regarding the palliative treatment of dysphagia, brachytherapy was shown to be more effective than stenting.

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Radio-Chemotherapy of Vulvar Cancer

Tumori Journal ◽

10.1177/030089169808400225 ◽

1998 ◽

Vol 84 (2) ◽

pp. 250-251 ◽

Cited By ~ 1

Author(s):

Roberto Zucali ◽

Francesco Raspagliesi ◽

Rado Kenda ◽

Laura Lozza ◽

Silvia Tana ◽

...

Keyword(s):

Multidisciplinary Approach ◽

Vulvar Cancer ◽

Locally Advanced ◽

Complete Response ◽

Pathological Examination ◽

Locally Advanced Tumors ◽

Cure Rates ◽

Radio Chemotherapy ◽

Advanced Tumors

Surgery alone, more or less demolitive, is the treatment of choice of vulvar cancers. Cure rates are high for early cancers only, while locally advanced tumors with or without inguinal adenopathies and recurrences have a bad prognosis. The excellent results of concurrent chemo-radiotherapy of anal cancers suggested to adopt the same approach for locally advanced vulvar cancers. The shrinkage of the tumor allowed surgery, often less demolitive than usual, and the pathological examination demonstrated an overall complete response in 40% of cases. Survival has been improved through this multidisciplinary approach. Patients not suitable for surgery obtained important remissions and an improved quality of life. Clinical experience at the Istituto Tumori of Milano is presented.

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The role of perioperative radiotherapy in gastric cancer

Oncology Reviews ◽

10.4081/oncol.2012.e23 ◽

2012 ◽

Vol 6 (2) ◽

pp. 23 ◽

Cited By ~ 1

Author(s):

Thales Paulo Batista ◽

Lucas Marque De Mendonça ◽

Ana Luiza Fassizoli-Fonte

Keyword(s):

Gastric Cancer ◽

Therapeutic Strategy ◽

Multimodal Therapy ◽

Early Stage ◽

Locally Advanced ◽

Early Stage Disease ◽

Stage Disease ◽

Locally Advanced Tumors ◽

Related Mortality

Gastric cancer is one of the most common neoplasms and a main cause of cancer-related mortality worldwide. Surgery remains the mainstay for cure and is considered for all patients with potentially curable disease. However, despite the fact that surgery alone usually leads to favorable outcomes in early stage disease, late diagnosis usually means a poor prognosis. In these settings, multimodal therapy has become the established treatment for locally advanced tumors, while the high risk of locoregional relapse has favored the inclusion of radiotherapy in the comprehensive therapeutic strategy. We provide a critical, non-systematic review of gastric cancer and discuss the role of perioperative radiation therapy in its treatment.

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The role of perioperative radiotherapy in gastric cancer

Oncology Reviews ◽

10.4081/oncol.2012.213 ◽

2012 ◽

pp. e23

Author(s):

Thales Paulo Batista ◽

Lucas Marque De Mendonça ◽

Ana Luiza Fassizoli-Fonte

Keyword(s):

Gastric Cancer ◽

Therapeutic Strategy ◽

Multimodal Therapy ◽

Early Stage ◽

Locally Advanced ◽

Early Stage Disease ◽

Stage Disease ◽

Locally Advanced Tumors ◽

Related Mortality

Gastric cancer is one of the most common neoplasms and a main cause of cancer-related mortality worldwide. Surgery remains the mainstay for cure and is considered for all patients with potentially curable disease. However, despite the fact that surgery alone usually leads to favorable outcomes in early stage disease, late diagnosis usually means a poor prognosis. In these settings, multimodal therapy has become the established treatment for locally advanced tumors, while the high risk of locoregional relapse has favored the inclusion of radiotherapy in the comprehensive therapeutic strategy. We provide a critical, non-systematic review of gastric cancer and discuss the role of perioperative radiation therapy in its treatment.

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Role of Panchatikta Panchaprasutik Niruha Vasti in Prediabetes A case report

International Journal of Ayurvedic Medicine ◽

10.47552/ijam.v11i3.1545 ◽

2020 ◽

Vol 11 (3) ◽

pp. 588-593

Author(s):

Poonam V Ashtankar ◽

Punam Sawarkar

Keyword(s):

Diabetes Prevention ◽

Palliative Treatment ◽

Relative Risk Reduction ◽

Early Stage ◽

Single Case ◽

Single Case Study ◽

Urine Sugar

Background: Prediabetes is an intermediate state of hyperglycemia with glycaemic parameters above normal but below the diabetes threshold. In Ayurveda, it is correlated with Prameha Poovaroopavastha. The risk of developing diabetes remains high with an annual conversion rate 5-10%. Many other studies have shown that the efficacy of lifestyle intervention in diabetes prevention with a relative risk reduction of 40-70% in prediabetes adults. If we treat this disease in early stage then it checks the further pathogenesis of disease. Aim and objectives: The aim of this study was to observe the efficacy of Panchatikta Panchaprasutik Niruha Vasti enema including Palliative treatment in prediabetes. Methods: It is a single case study of 55 years old male patient who was diagnosed with prediabetes correlated as Prameha Poorvaroopa from 1 year approached to Ayurvedic hospital and was treated Panchatikta Panchaprasutik Niruha Vasti. The treatment was continued for consecutive 15 days. Results: After 15days changes were observed in symptoms as well as reduction was seen in blood and urine sugar level and overall quality of life of patient was improved. Conclusion: Patient got satisfactory relief in symptoms as well as objective parameters after 15 days.

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Quality of life and emotional distress in early stage and locally advanced cervical cancer patients: A prospective, longitudinal study

Gynecologic Oncology ◽

10.1016/j.ygyno.2011.09.041 ◽

2012 ◽

Vol 124 (3) ◽

pp. 389-394 ◽

Cited By ~ 70

Author(s):

Gabriella Ferrandina ◽

Giovanna Mantegna ◽

Marco Petrillo ◽

Gilda Fuoco ◽

Laura Venditti ◽

...

Keyword(s):

Quality Of Life ◽

Cervical Cancer ◽

Longitudinal Study ◽

Early Stage ◽

Locally Advanced ◽

Advanced Cervical Cancer ◽

Prospective Longitudinal Study ◽

Locally Advanced Cervical Cancer ◽

Prospective Longitudinal

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Hyperfractionated-Accelerated Radiotherapy Followed by Radical Surgery in Locally Advanced Tumors of the Oral Cavity

Strahlentherapie und Onkologie ◽

10.1007/s00066-006-1472-5 ◽

2006 ◽

Vol 182 (3) ◽

pp. 157-163 ◽

Cited By ~ 3

Author(s):

Ulrike Hoeller ◽

Iris Biertz ◽

Sebastian Flinzberg ◽

Silke Tribius ◽

Reiner Schmelzle ◽

...

Keyword(s):

Oral Cavity ◽

Radical Surgery ◽

Locally Advanced ◽

Accelerated Radiotherapy ◽

Locally Advanced Tumors ◽

Advanced Tumors

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A ROLE OF AYURVEDA IN THE MANAGEMENT OF APASMARA (EPILEPSY): A CASE STUDY

International Journal of Research in Ayurveda and Pharmacy ◽

10.7897/2277-4343.1204100 ◽

2021 ◽

Vol 12 (4) ◽

pp. 24-29

Author(s):

Shruti . ◽

C V Rajashekhar ◽

Manjunatha Adiga

Keyword(s):

Antiepileptic Drugs ◽

Palliative Treatment ◽

Cognitive Level ◽

Frequent Seizure ◽

Seizure Attack ◽

Seizure Attacks

Apasmara (epilepsy) is defined as the apagama (deterioration) of smriti (memory) associated with bibhasta cheshta (seizures) due to derangement of dhi and satwa, mainly related to vata and rajo dosha vitiation, which effects both Sharira (body) and Mana (mind). The present antiepileptic drugs control the seizure attack, but long-term use generates adverse effect at cognitive level and leads to behavioral disorders, hence there is need of safe and effective treatment which not only controls seizure attack but helps to cure the disease. A 44-year-old man approached Kayachikitsa OPD with the complaints of frequent seizure attacks, since from at the age of one and half year with regular oral antiepileptic drugs medications (allopathic), the dose of medications increasing yearly and he was not satisfied with treatment, so he was advised with Panchakarma treatment starting from Deepana, Pachana, Vamana (medicated emesis), Virechana (medicated purgation), Basti (medicated enema), Shirodhara along with palliative treatment. After each treatment it was observed that the patient was satisfied with treatment and the complaints of seizure attack reduced in frequency and duration with improved quality of life. Palliative treatment was advised to continue along with modern medications.

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