scholarly journals Unequal Rates of Y Chromosome Gene Divergence during Speciation of the Family Ursidae

2008 ◽  
Vol 25 (7) ◽  
pp. 1344-1356 ◽  
Author(s):  
Shigeki Nakagome ◽  
Jill Pecon-Slattery ◽  
Ryuichi Masuda
Keyword(s):  
Y Chromosome ◽  
Gene Divergence ◽  
Chromosome Gene ◽  
The Family ◽  
Unequal Rates

Fertile females of the mole Talpa occidentalis are phenotypic intersexes with ovotestes

Development ◽  
1993 ◽  
Vol 118 (4) ◽  
pp. 1303-1311 ◽  
Author(s):  
R. Jimenez ◽  
M. Burgos ◽  
A. Sanchez ◽  
A.H. Sinclair ◽  
F.J. Alarcon ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Sex Reversal ◽  
Chromosome Gene ◽  
Different Populations ◽  
Testis Determining Gene

We investigated the origin of XX sex reversal in the insectivorous mole Talpa occidentalis. Cytogenetic, histological and hormonal studies indicate that all XX individuals analyzed from two different populations are true hermaphrodites, with ovotestes. This suggests that XX sex reversal may be the norm in this species. The intersexes are functional fertile females and the trait is transmitted and maintained in the population. Intersexes lack the Y chromosome gene SRY (sex determining region Y gene), shown to be the testis determining gene. These results suggest that XX intersex moles may have arisen from a mutation of a gene located downstream from SRY/TDY in the testis determining pathway.

scholarly journals Forensic application of Y-chromosomal STR analysis in Lithuanian population

Biologija ◽  
2015 ◽  
Vol 61 (2) ◽  
Author(s):  
Giedrė Ruzgaitė ◽  
Marija Čaplinskienė ◽  
Rima Baranovienė ◽  
Jūratė Jankauskienė ◽  
Jolanta Kukienė ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Gene Pool ◽  
Haplotype Diversity ◽  
Haplotype Frequency ◽  
Reference Database ◽  
Match Probability ◽  
Str Analysis ◽  
Str Markers ◽  
Forensic Casework ◽  
Chromosome Gene

This paper presents a comprehensive Y-chromosomal STR haplotype analysis in the Lithuanian population in order to evaluate Lithuanians’ Y chromosome diversity, to infer genetic relations between Lithuanian and other European neighbouring populations and to introduce population reference data for generation of reliable Y-STR haplotype frequency estimates to be used in the quantitative assessment of Y-STR haplotype match in the forensic casework. Data were collected from the peripheral blood samples of 194 unrelated males throughout various regions of Lithuania. The amplification of 17 Y-STRs was carried out in one multiplex PCR using an  AmpFlSTR® Yfiler<sup>TM</sup> PCR Amplication Kit according to the supplier’s protocol. The results indicated that the Y-chromosomal haplotype diversity in the Lithuanian population rises as the  number of the  analyzed Y-STRs is increased. However, all additional Y-STR loci are not hypervariable and only their whole makes a large diversity of Y-STR haplotypes in Lithuanian males. The  analysis of molecular variance revealed low but significant interpopulation differences except the pair of Lithuanian and Latvian populations. The  phylogenetic analysis showed that the  clustered Y chromosome gene pool of Lithuanians and Latvians has a closer phylogenetic relation to Russian and Estonian populations and is less genetically related to other neighbouring populations of Belarus and Poland. Yet Y-STRs alleles and haplotypes differentiate effectively inside the  Lithuanian population and between Lithuanians and its geographical neighbours excluding the  Latvian population. Comparison of the Y-STR data suggests that Lithuanian and Latvian populations are closely related not only by geography and language but also by the Y chromosome gene pool represented by forensic Y-STR markers. Consequently, more forensic Y-STR markers should be included in the Y-STR haplotype in order to achieve a resolution between the  Y chromosomes of Lithuanian and Latvian males. Lithuanian Y-STR haplotype data were submitted to the 34th release of the Y-STR Haplotype Reference Database 3.0 for match probability calculations in the forensic casework.

Inhibition of Human Y Chromosome Gene, SRY, Promotes Naïve State of Human Pluripotent Stem Cells

2019 ◽  
Vol 18 (12) ◽  
pp. 4254-4261 ◽  
Author(s):  
Sara Taleahmad ◽  
Mehdi Alikhani ◽  
Sepideh Mollamohammadi ◽  
Meisam Yousefi ◽  
Adeleh Taei ◽  
...  
Keyword(s):  
Stem Cells ◽  
Y Chromosome ◽  
Pluripotent Stem Cells ◽  
Human Pluripotent Stem Cells ◽  
Chromosome Gene ◽  
Human Y Chromosome

Similarities and distinctions in Y chromosome gene pool of Western Slavs

2010 ◽  
Vol 142 (4) ◽  
pp. 540-548 ◽  
Author(s):  
Marcin Woźniak ◽  
Boris Malyarchuk ◽  
Miroslava Derenko ◽  
Tomas Vanecek ◽  
Jan Lazur ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Gene Pool ◽  
Chromosome Gene

scholarly journals Quantitative analysis of Y-Chromosome gene expression across 36 human tissues

2020 ◽  
Vol 30 (6) ◽  
pp. 860-873 ◽  
Author(s):  
Alexander K. Godfrey ◽  
Sahin Naqvi ◽  
Lukáš Chmátal ◽  
Joel M. Chick ◽  
Richard N. Mitchell ◽  
...  
Keyword(s):  
Gene Expression ◽  
Quantitative Analysis ◽  
Y Chromosome ◽  
Human Tissues ◽  
Chromosome Gene

Identification of Donor-Derived Cells in Organ Transplants by in Vitro Amplification of Y-Chromosome Gene Using Polymerase Chain Reaction

1994 ◽  
Vol 3 (1_suppl) ◽  
pp. 27-28 ◽  
Author(s):  
Yasuhiko Fukuda ◽  
Hirotaka Tashiro ◽  
Shuji Hoshino ◽  
Akinori Kimura ◽  
Kiyohiko Dohi
Keyword(s):  
Polymerase Chain Reaction ◽  
Y Chromosome ◽  
Organ Transplants ◽  
Chain Reaction ◽  
Chromosome Gene ◽  
Polymerase Chain

scholarly journals Y chromosome gene copy number and lack of autism phenotype in a male with an isodicentric Y chromosome and absent NLGN4Y expression

2019 ◽  
Vol 180 (7) ◽  
pp. 471-482 ◽  
Author(s):  
Judith L. Ross ◽  
Luke Bloy ◽  
Timothy P. L. Roberts ◽  
Judith Miller ◽  
Chao Xing ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Copy Number ◽  
Gene Copy Number ◽  
Gene Copy ◽  
Chromosome Gene ◽  
Autism Phenotype

scholarly journals Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow

2004 ◽  
Vol 50 (1) ◽  
pp. 49-51 ◽  
Author(s):  
Anjana Saha ◽  
Swarkar Sharma ◽  
Audesh Bhat ◽  
Awadesh Pandit ◽  
Ramesh Bamezai
Keyword(s):  
Gene Flow ◽  
Y Chromosome ◽  
Genetic Affinity ◽  
Population Groups ◽  
Chromosome Gene

scholarly journals The Effect of Hybridization on Dosage Compensation in Member Species of the Anopheles gambiae Species Complex

2018 ◽  
Author(s):  
Kevin C. Deitz ◽  
Willem Takken ◽  
Michel A. Slotman
Keyword(s):  
Sex Determination ◽  
Anopheles Gambiae ◽  
Y Chromosome ◽  
X Chromosome ◽  
Dosage Compensation ◽  
Sex Chromosomes ◽  
Species Complex ◽  
F1 Hybrids ◽  
Chromosome Gene ◽  
Heterogametic Sex

AbstractDosage compensation has evolved in concert with Y-chromosome degeneration in many taxa that exhibit heterogametic sex chromosomes. Dosage compensation overcomes the biological challenge of a "half dose" of X chromosome gene transcripts in the heterogametic sex. The need to equalize gene expression of a hemizygous X with that of autosomes arises from the fact that the X chromosomes retain hundreds of functional genes that are actively transcribed in both sexes and interact with genes expressed on the autosomes. Sex determination and heterogametic sex chromosomes have evolved multiple times in Diptera, and in each case the genetic control of dosage compensation is tightly linked to sex determination. In the Anopheles gambiae species complex (Culicidae), maleness is conferred by the Y-chromosome gene Yob, which despite its conserved role between species is polymorphic in its copy number between them. Previous work demonstrated that male An. gambiae s.s. males exhibit complete dosage compensation in pupal and adult stages. In the present study we have extended this analysis to three sister species in the An. gambiae complex: An. coluzzii, An. arabiensis, and An. quadriannulatus. In addition, we analyzed dosage compensation in bi-directional F1 hybrids between these species to determine if hybridization results in the mis-regulation and disruption of dosage compensation. Our results confirm that dosage compensation operates in the An. gambiae species complex through the hyper-transcription of the male X chromosome. Additionally, dosage compensation in hybrid males does not differ from parental males, indicating that hybridization does not result in the mis-regulation of dosage compensation.

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