MO774PREDICTIVE FACTORS FOR PROSTHESIC ARTERIOVENOUS FISTULA OPTION BY DUPLEX DOPPLER ULTRASOUND VASCULAR MAPPING

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Joana Marques ◽  
Tiago Pereira ◽  
Rui Barata ◽  
Miguel Bigotte Vieira ◽  
Fernando Nolasco
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Arteriovenous Fistula ◽  
Doppler Ultrasound ◽  
Vascular Access ◽  
Distributed Data ◽  
Multivariate Logistic Regression ◽  
Black Race ◽  
Vascular Mapping ◽  
Duplex Doppler

Abstract Background and Aims Vascular access (VA) remains the lifeline for hemodialysis (HD) patients. Arteriovenous fistulas (AVF) are recommended over prosthesic arteriovenous fistula (PAF). However, the choice of the type of VA still reflects local practice differences and patient-specific demographic and clinical factors. Duplex Doppler ultrasound (DDU) has been shown to be useful in evaluation of both structural and functional aspects of the peripheral vessels, and is emerging as the preferred method for VA planning. Our aim was to find predictive factors for PAF creation in our population, i.e. when AVF was not feasible. Method We retrospectively analysed a cohort of chronic kidney disease patients who underwent DDU vascular mapping for preoperative planning of HD access at a tertiary referral centre from 2019 to 2020. All the exams were performed by the same DDU operator. Demographic, clinical and DDU characteristics were studied. Continuous variables were recorded as means (±SD) for normally distributed data or as medians (interquartile ranges) for non-normally distributed data. Comparisons were made using t tests or Wilcoxon rank sum tests as appropriate. Categorical variables were evaluated by frequency distribution and recorded as proportions. Comparisons were made using the x2 test. Unadjusted and adjusted multivariate logistic regression models were fitted to identify risk factors to PAF creation due to not being a good candidate for AVF. Results A total of 252 patients were included. The mean age was 65±16 years, 144 (57%) were male, 211 (84%) where white, 40 (16%) were black and 1 (0.4%) was asian. Two hundred and thirty seven (94%) patients were right-handed and 186 (74%) were being evaluated for the first vascular access. The majority had arterial hypertension (HT) (205 (81%)); 98 (39%) had Diabetes Mellitus (DM), 89 (35%) were current or past smoker and 72 (29%) were obese. Most patients were considered appropriate candidates for AVF (207, 82%), whereas 45 (18%) were assigned to PAF. Figure 1 compares the DDU’s arterial indexes of each group. In a multivariate logistic regression model adjusted for age, sex, HT, DM and obesity, black race was found to be a predictor of being a candidate for PAV creation (OR 2.46; CI 95% 1.05-5.71; p-value 0.036). Conclusion Our study revealed that black race is an independent factor for PAV creation even after adjusting for classic risk factors as age, DM or HT. Long known insidious factors, such as poor socioeconomic status or poor access to medical care, have been pointed as justifiers to this disparity. However, facing the PAF-associated risks, we believe that further work must be done to clarify potential involved anatomical factors and potential reversible factors. Those patients have been described throughout the literature as presenting with higher risk of VA failure and severe peripheral arterial disease. In parallel we found that radial and ulnar arteries diameters and radial pulse wave velocity (PWV) in DDU were significantly lower in PAV-submitted patients, suggesting distal arterial compromise and stiffness. Our work has some limitations: neither vein parameters nor VA outcomes were analysed. However, it introduces a relationship between the black race and worse arterial indexes, and their impact on the choice of type of VA, as they seem not to be good candidates for AVF.

scholarly journals MO773THE VASCULAR REALITY BEHIND ULTRASOUND VASCULAR MAPPING: WHICH FACTORS PREDICT THE BEST CANDIDATES FOR RADIOCEPHALIC ARTERIOVENOUS FISTULA?

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Rui Barata ◽  
Tiago Pereira ◽  
Joana Marques ◽  
Miguel Bigotte Vieira ◽  
Fernando Nolasco
Keyword(s):  
Logistic Regression ◽  
Arteriovenous Fistula ◽  
Pulse Wave ◽  
Arterial Calcification ◽  
P Value ◽  
Distributed Data ◽  
Obese Patients ◽  
Multivariate Logistic Regression ◽  
Vascular Mapping ◽  
Male Sex

Abstract Background and Aims Vascular accesses (VA) are key components for efficient hemodialysis. Arteriovenous fistulas (AVF) are recommended over arteriovenous graft (AVG), but deciding the type and location of a VA is challenging. Preoperative vascular mapping before surgical creation of VA, especially trough ultrasound (US), is helpful in this decision, contributing to improve AVF e AVG outcomes. Our study aims to identify patient factors associated with appropriate arterial US parameters that predict feasibility for radiocephalic fistula creation. Method We analyzed a cohort of chronic kidney disease patients who underwent US vascular mapping for preoperative planning of dialysis access from 2019 to 2020, in a tertiary referral center. Patients were characterized based on its demographical characteristics, and the presence of diabetes, hypertension, obesity, and smoking. Arterial indicators were analyzed by ultrasound techniques in both upper arms, including radial, ulnar and brachial arteries. Those indicators included arterial diameter, calcification, doppler wave form, and pulse wave velocity. Continuous variables were recorded as means (±SD) for normally distributed data and as medians (interquartile ranges) for nonnormally distributed data. Comparisons were made using t tests or Wilcoxon rank sum tests as appropriate. Categorical variables were examined by frequency distribution and recorded as proportions. Comparisons were made using the x2 test. Unadjusted and adjusted multivariate logistic regression models were fitted to identify predictors for a good candidate for radiocephalic arteriovenous fistula. Results A total of 252 patients were included. The mean age was 65±16 years, 144 (57%) were male, 211 (84%) where white, 40 (16%) were black, and 1 (0.4%) was asian. Most had arterial hypertension (205, 81%), 98 (39%) had diabetes mellitus, 89 (35%) were smokers, and 72 (29%) were obese. The majority of patients were attending for the first VA (186; 74%). Most patients were considered appropriate candidates for arteriovenous fistula creation (207, 82%), whereas 45 (18%) were assigned to PTFE graft. Obesity and male sex were found to be predictors for being a good candidate for radiocephalic arteriovenous fistula in a multivariate logistic regression model adjusted for age, hypertension, and diabetes (OR 3.21, CI 95% 1.63-6.32, p-value 0.001 and OR 2.09, CI 95% 1.07-4.08, p-value 0.031, respectively). Figure 1 presents the arterial indicators analyzed during ultrasound mapping, including both upper limbs. Conclusion Our results show that obesity and male sex are predictors for radiocephalic arteriovenous fistula creation. While female sex has long been known to be a risk factor for VA failure, possibly because of worse arterial indicators, an association between obesity and higher probability of distal AVF creation has not been established yet. Comparison between arterial indicators in obese and nonobese patients shows that obese patients generally have better arterial indicators, especially higher pulse wave velocities, and less arterial calcification. Given that some studies show an association between obesity and shorter fistula survival (due to higher secondary failure rate), our results may come as. A possible explanation for this difference is that obesity may exert a physical protective effect of the forearm vascular bed against iatrogenic damage (blood sampling and vessel cannulation). Besides that, factors other than vascular indicators may contribute to ulterior VA failure, like the proinflammatory state in obese patients and its consequent myointimal hyperplasia. However, our conclusions are based on preoperative findings, and not on VA outcomes, especially its patency and complications. Moreover, which further help to determine the better location for a VA creation, were not evaluated in this study.

Baseline characteristics of arm vessels by preoperative duplex ultrasonography in Korean patients for hemodialysis vascular access

2019 ◽  
Vol 20 (6) ◽  
pp. 646-651
Author(s):  
Minji Cho ◽  
Jung Sun Kim ◽  
Sungsin Cho ◽  
Won Pyo Cho ◽  
Chanjoong Choi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Arteriovenous Fistula ◽  
Vascular Access ◽  
Multivariate Logistic Regression Analysis ◽  
Duplex Ultrasonography ◽  
Multivariate Logistic Regression ◽  
Baseline Characteristics ◽  
End Stage ◽  
Fistula Maturation ◽  
Arteriovenous Fistula Maturation

Background: Preoperative mapping with duplex ultrasonography is crucial for successful vascular access creation for hemodialysis. The aims of this study are to assess the baseline characteristics of arm vessels by preoperative duplex ultrasonography in Korean patients, to find out a preoperative duplex ultrasonography parameter precluding distal arteriovenous fistula creation, to assess the maturation failure rate of arteriovenous fistulas, and to identify associated risk factors. Methods: Preoperative duplex ultrasonography mapping for vascular access creation was done in all patients with end-stage renal diseases during the year 2015. The baseline data of duplex ultrasonography were retrospectively analyzed with follow-up clinical data. Results: A total of 299 end-stage renal disease patients (mean age = 62 years, 62% male) were included. On preoperative duplex ultrasonography, mean diameters of radial artery and cephalic vein at wrist were 2.03 and 2.40 mm in the non-dominant arm and 2.10 and 2.26 mm in the dominant arm, respectively. The most common reason for precluding radial-cephalic arteriovenous fistula at wrist was small-sized cephalic vein. Multivariate logistic regression analysis revealed that the risk factors for inadequate vessels were warfarin treatment, old age (⩾75 years), and peripheral arterial occlusive disease. The rate of arteriovenous fistula maturation failure was 21% and vein diameter <2.5 mm was the only risk factor for arteriovenous fistula maturation failure by multivariate logistic regression analysis. Conclusion: Preoperative duplex ultrasonography evaluation is important to find out inadequate vessels for native arteriovenous fistula and to determine the location of vascular access.

Short-Term Outcomes Following Removal of Infected Hernia Mesh

2021 ◽  
pp. 000313482110241
Author(s):  
Christine Tung ◽  
Junko Ozao-Choy ◽  
Dennis Y. Kim ◽  
Christian de Virgilio ◽  
Ashkan Moazzez
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Logistic Regression ◽  
Body Mass ◽  
Smoking History ◽  
Multivariate Logistic Regression ◽  
Short Term ◽  
Mesh Removal ◽  
Mesh Placement ◽  
Infected Mesh

There are limited studies regarding outcomes of replacing an infected mesh with another mesh. We reviewed short-term outcomes following infected mesh removal and whether placement of new mesh is associated with worse outcomes. Patients who underwent hernia repair with infected mesh removal were identified from 2005 to 2018 American College of Surgeons-National Surgical Quality Improvement Program database. They were divided into new mesh (Mesh+) or no mesh (Mesh-) groups. Bivariate and multivariate logistic regression analyses were used to compare morbidity between the two groups and to identify associated risk factors. Of 1660 patients, 49.3% received new mesh, with higher morbidity in the Mesh+ (35.9% vs. 30.3%; P = .016), but without higher rates of surgical site infection (SSI) (21.3% vs. 19.7%; P = .465). Mesh+ had higher rates of acute kidney injury (1.3% vs. .4%; P = .028), UTI (3.1% vs. 1.3%, P = .014), ventilator dependence (4.9% vs. 2.4%; P = .006), and longer LOS (8.6 vs. 7 days, P < .001). Multivariate logistic regression showed new mesh placement (OR: 1.41; 95% CI: 1.07-1.85; P = .014), body mass index (OR: 1.02; 95% CI: 1.00-1.03; P = .022), and smoking (OR: 1.43; 95% CI: 1.05-1.95; P = .025) as risk factors independently associated with increased morbidity. New mesh placement at time of infected mesh removal is associated with increased morbidity but not with SSI. Body mass index and smoking history continue to contribute to postoperative morbidity during subsequent operations for complications.

scholarly journals Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases

2020 ◽  
Vol 8 ◽  
Author(s):  
Chen Dong ◽  
Minhui Zhu ◽  
Luguang Huang ◽  
Wei Liu ◽  
Hengxin Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Treatment Failure ◽  
Logistic Regression Analysis ◽  
Disease Duration ◽  
Multivariate Logistic Regression Analysis ◽  
Tissue Expansion ◽  
Multivariate Logistic Regression ◽  
Hematoma Evacuation

Abstract Background Tissue expansion is used for scar reconstruction owing to its excellent clinical outcomes; however, the complications that emerge from tissue expansion hinder repair. Infection is considered a major complication of tissue expansion. This study aimed to analyze the perioperative risk factors for expander infection. Methods A large, retrospective, single-institution observational study was carried out over a 10-year period. The study enrolled consecutive patients who had undergone tissue expansion for scar reconstruction. Demographics, etiological data, expander-related characteristics and postoperative infection were assessed. Univariate and multivariate logistic regression analysis were performed to identify risk factors for expander infection. In addition, we conducted a sensitivity analysis for treatment failure caused by infection as an outcome. Results A total of 2374 expanders and 148 cases of expander infection were assessed. Treatment failure caused by infection occurred in 14 expanders. Multivariate logistic regression analysis identified that disease duration of ≤1 year (odds ratio (OR), 2.07; p &lt; 0.001), larger volume of expander (200–400 ml vs &lt;200 ml; OR, 1.74; p = 0.032; &gt;400 ml vs &lt;200 ml; OR, 1.76; p = 0.049), limb location (OR, 2.22; p = 0.023) and hematoma evacuation (OR, 2.17; p = 0.049) were associated with a high likelihood of expander infection. Disease duration of ≤1 year (OR, 3.88; p = 0.015) and hematoma evacuation (OR, 10.35; p = 0.001) were so related to high risk of treatment failure. Conclusions The rate of expander infection in patients undergoing scar reconstruction was 6.2%. Disease duration of &lt;1 year, expander volume of &gt;200 ml, limb location and postoperative hematoma evacuation were independent risk factors for expander infection.

Atypical presentation of fistula dysfunction due to brachial arterial embolization mimicking stroke

2022 ◽  
pp. 112972982110676
Author(s):  
Rita Vicente ◽  
Laura Rodriguez ◽  
Joaquim Vallespín ◽  
Carolina Rubiella ◽  
Jose Ibeas
Keyword(s):  
Arteriovenous Fistula ◽  
Doppler Ultrasound ◽  
Vascular Access ◽  
Brachial Artery ◽  
Arterial Embolization ◽  
Limb Ischemia ◽  
Artery Occlusion ◽  
Bedside Ultrasound ◽  
Computed Tomographic ◽  
Ultrasound Evaluation

Vascular access thrombosis is an important complication with great impact on access patency and, consequently, on a patient’s quality of life and survival. We report the case of a 73-year-old woman with chronic kidney disease on hemodialysis with a radiocephalic arteriovenous fistula on the right arm that was brought to the emergency department with decreased strength in her right arm, ipsilateral hypoesthesia and facial hemi-hypoesthesia. The patient was given a brain computed tomographic scan that did not confirm suspicion of stroke. On re-examination, the patient had new-onset pain at arteriovenous fistula level, and her right arm was cold and pale. The nephrology department was called for arteriovenous fistula evaluation. On physical examination, her forearm fistula had a decreased thrill and arm elevation exacerbated its paleness. A bedside ultrasound was performed for arteriovenous fistula assessment. Doppler ultrasound revealed: partial thrombosis at brachial bifurcation, a flow of 80–105 mL/min at brachial artery level and a radial artery with a damped waveform. Anastomosis and draining vein were permeable. In this case, the diagnosis of acute embolic brachial artery occlusion was made by a fast bedside ultrasound evaluation. The patient underwent thromboembolectomy with Fogarty technique, recovering fistula thrill, radial and cubital pulses. Thromboembolism of the fistula feeding artery is a rare cause of vascular access thrombosis and it is rarely mentioned in the literature. In this report, failure to recognize the upper limb ischemia would have led to delayed treatment, potentially resulting in the fistula’s complete thrombosis and further limb ischemia. We highlight the importance of a diagnosis method like Doppler ultrasound, which allows for rapid evaluation at the patient’s bedside.

scholarly journals 10-Year Renal Function Trajectories in Community-Dwelling Older Adults: Exploring the Risk Factors for Different Patterns

2018 ◽  
Vol 7 (10) ◽  
pp. 373
Author(s):  
Chia-Ter Chao ◽  
Yung-Ming Chen ◽  
Fu-Hui Ho ◽  
Kun-Pei Lin ◽  
Jen-Hau Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Logistic Regression ◽  
Renal Function ◽  
Estimated Glomerular Filtration Rate ◽  
Community Dwelling ◽  
Multivariate Logistic Regression ◽  
Improve Risk Stratification ◽  
Leukocyte Counts ◽  
Community Dwelling Older Adults

Longitudinal changes of renal function help inform patients’ clinical courses and improve risk stratification. Rare studies address risk factors predicting changes in estimated glomerular filtration rate (eGFR) over time in older adults, particularly of Chinese ethnicity. We identified prospectively enrolled community-dwelling older adults (≥65 years) receiving annual health examinations between 2005 and 2015 with serum creatinine available continuously in a single institute, and used linear regression to derive individual’s annual eGFR changes, followed by multivariate logistic regression analyses to identify features associated with different eGFR change patterns. Among 500 elderly (71.3 ± 4.2 years), their mean annual eGFR changes were 0.84 ± 1.67 mL/min/1.73 m2/year, with 136 (27.2%) and 238 (47.6%) classified as having downward (annual eGFR change <0 mL/min/1.73 m2/year) and upward eGFR (≥1 mL/min/1.73 m2/year) trajectories, respectively. Multivariate logistic regression showed that higher age (odds ratio (OR) 1.08), worse renal function (OR 13.2), and more severe proteinuria (OR 9.86) or hematuria (OR 3.39) were predictive of a declining eGFR while greater waist circumference (OR 1.06) and higher leukocyte counts (OR 1.21) were predictive of an uprising 10-year eGFR. These findings elucidate important features associated with geriatric renal function variations, which are expected to improve their renal care.

scholarly journals Risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jin-Xi Huang ◽  
Song-Ming Hong ◽  
Qiang Chen ◽  
Zeng-Chun Wang ◽  
Dian-Ming Wu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Birth Weight ◽  
Oesophageal Atresia ◽  
Prognostic Nutritional Index ◽  
Anastomotic Stenosis ◽  
Multivariate Logistic Regression ◽  
One Stage ◽  
Nutritional Index ◽  
Anastomotic Fistula

Abstract Background Oesophageal atresia is a congenital malformation of the oesophagus and a serious malformation of the digestive system, postoperative complications include acute respiratory failure, pneumonia, anastomotic fistula, anastomotic stenosis, tracheal stenosis, gastroesophageal reflux and eosinophilic oesophagitis, anastomotic fistula is one of the important causes of postoperative death. The objective of this study is to identify the risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia. Methods A retrospective analysis was performed on the clinical data of 107 children with congenital oesophageal atresia who underwent one-stage anastomosis in our hospital from January 2013 to December 2018. Single-factor and multivariate logistic regression analyses were performed to determine the risk factors for anastomotic fistula and anastomotic stenosis. Results A total of 107 children with oesophageal atresia underwent one-stage anastomosis, and the incidence of anastomotic fistula was 26.2%. The probability of anastomotic stenosis in the long term was 52.3%, and the incidence of refractory stenosis (dilation ≥5 times) was 13.1%. Analysis of the clinical count data in the anastomotic fistula group and non-anastomotic fistula group showed that preoperative albumin (F = 4.199, P = 0.043), low birth weight (F = 7.668, P = 0.007) and long gap defects (F = 6.107, P = 0.015) were risk factors for postoperative anastomotic fistula. Further multivariate logistic regression analysis showed that low birth weight (Wald2 = 4.499, P = 0.034, OR = 2.775) and long gap defects (Wald2 = 6.769, P = 0.009, OR = 4.939) were independent risk factors for postoperative anastomotic fistula. Premature delivery (F = 5.338, P = 0.023), anastomotic fistula (F = 11.381, P = 0.001), endoscopic surgery (F = 6.343, P = 0.013), preoperative neutrophil count (F = 8.602, P = 0.004), preoperative low albumin (F = 8.410, P = 0.005), and a preoperative prognostic nutritional index < 54 (F = 5.54, P = 0.02) were risk factors for refractory anastomotic stenosis in children. Further multivariate logistic regression analysis showed that postoperative anastomotic fistula (Wald2 = 11.417, P = 0.001, OR = 8.798), endoscopic surgery (Wald2 = 9.633, P = 0.002, OR = 4.808), and a prognostic nutritional index < 54 (Wald2 = 4.540, P = 0.002, OR = 2.3798) were independent risk factors for refractory anastomotic stenosis. Conclusion Low birth weight and long gap defects are important predictors of postoperative anastomotic fistula, and the possibility of refractory anastomotic stenosis should be considered. The long-term risk of anastomotic stenosis was increased in children undergoing endoscopic surgery and in those with a preoperative prognostic nutritional index < 54.

scholarly journals Predictive risk factors for worse outcomes in COVID-19 patients with different clinical features at baseline

2021 ◽  
Author(s):  
Elisabetta Schiaroli ◽  
Anna Gidari ◽  
Giovanni Brachelente ◽  
Sabrina Bastianelli ◽  
Alfredo Villa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Critical Illness ◽  
Serum Ferritin ◽  
Logistic Regression Analysis ◽  
Severe Disease ◽  
Multivariate Logistic Regression Analysis ◽  
Multivariate Logistic Regression ◽  
Neutrophil Lymphocyte Ratio

IntroductionCOVID-19 is characterized by a wide range of clinical expression and by possible progression to critical illness and death. Therefore it is essential to identify risk factors predicting progression towards serious and fatal diseases. The aim of our study was to identify laboratory predictive markers of clinical progression in patients with moderate/severe disease and in those with acute respiratory distress syndrome (ARDS).Material and methodsUsing electronic medical records for all demographic, clinical and laboratory data, a retrospective study on all consecutive patients with COVID-19 admitted to the Infectious Disease Clinic of Perugia was performed. The PaO2/FiO2 ratio (P/F) assessment cut‑off of 200 mm Hg was used at baseline to categorize the patients into two clinical groups. The progression towards invasive ventilation and/or death was used to identify critical outcome. Statistical analysis was performed. Multivariate logistic regression analysis was adopted to identify risk factors of critical illness and mortality.ResultsIn multivariate logistic regression analysis neutrophil/lymphocyte ratio (NLR) was the only significant predictive factor of progression to a critical outcome (p = 0.03) and of in-hospital mortality (p = 0.03). In ARDS patients no factors were associated with critical progression. Serum ferritin > 1006 ng/ml was the only predictive value of critical outcome in COVID-19 subjects with moderate/severe disease (p = 0.02).ConclusionsNeutrophil/lymphocyte ratio and serum ferritin are the only biomarkers that can help to stratify the risk of severity and mortality in patients with COVID-19.

scholarly journals Factors associated with depression in the patients with diabetes mellitus type 2

2019 ◽  
Vol 76 (11) ◽  
pp. 1178-1183 ◽  
Author(s):  
Admir Sabanovic ◽  
Natasa Maksimovic ◽  
Mirjana Stojanovic-Tasic ◽  
Marijan Bakic ◽  
Anita Grgurevic
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Diabetes Mellitus Type 2 ◽  
Multivariate Logistic Regression Analysis ◽  
Multivariate Logistic Regression ◽  
Factors Associated

Background/Aim. The assessment of association of depression and diabetes mellitus type 2 using the Patient Health Questionaire (PHQ-9) has not been done in Montenegro. The aim of this study was to assess the prevalence of depression in the patients with type 2 diabetes mellitus, and to identify the risk factors associated with the presence of depression. Methods. A cross-sectional study was conducted at the General Hospital in Bijelo Polje, from July to September, 2015. It included 70 patients over 35 years of age with the diagnosis of diabetes for at least six months. For the assessment of depression presence and intensity PHQ?9 was used. All variables associated with the presence of depression at a significance level of p < 0.05 were included into the final method of the multivariate logistic regression analysis. Results. Comorbidities were statistically significant more frequent among patients with depression (?2 = 5.40; p = 0.020). Duration of diabetes over five years was significantly associated with depression (?2 = 12.48; p < 0.001). Depression occurred more frequently among physically inactive subjects (?2 = 10.74; p = 0.005). The presence of diabetic polyneuropathy (?2 = 6.04; p = 0.014) and cataract (?2 = 5.351; p = 0.021) were also significantly associated with depression. A multivariate logistic regression analysis showed that the duration of diabetes over five years and presence of cataract were independently associated with depression. Conclusion. The risk factors for depression among the subjects with diabetes were disease duration more than five years and the presence of cataract. Since depression is a serious disease and can be a risk factor for many chronic diseases, the best way of prevention is its early detection and treatment.

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