SURG-04. CRANIAL BONE DEFECTS IN PATIENTS TREATED WITH TTFIELDS: A CASE SERIES

Abstract Background This prospective study aims to evaluate the mid-term clinical outcomes and radiographic stability of two different types of cementless trabecular titanium acetabular components in total hip revision surgery. Methods Between December 2008 and February 2017, 104 cup revisions were performed using trabecular titanium revision cups. Mean age of patients was 70 (range 29–90; SD 11) years. The majority of revisions were performed for aseptic loosening (86 cases, 82.69%), but in all the other diagnoses (18 cases), a significant bone loss (Paprosky type II or III) was registered preoperatively. Bone defects were classified according to Paprosky acetabular classification. We observed 53 type II defects and 42 type III defects. Cups were chosen according to the type of defect. Results Average follow-up was 91 (range 24–146) months. Mean Harris Hip Score (HHS) improved from 43.7 (range 25–70; SD 9) preoperatively to 84.4 (range 46–99; SD 7.56) at last follow-up. One (1.05%) cup showed radiographic radiolucent lines inferior to 2 mm and was clinically asymptomatic. One (1.05%) cup was loose and showed periacetabular allograft reabsorption. Kaplan–Meier survivorship was assessed to be 88.54% (95% CI 80.18–93.52%) at 71 months, with failure of the cup for any reason as the endpoint. Conclusion Trabecular titanium revision cups showed good clinical and radiographic results at mid-term follow-up in Paprosky type II and III bone defects. Level of evidence Level IV prospective case series

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Management of Cranial Bone Defects

Journal of Craniofacial Surgery ◽

10.1097/scs.0b013e3182a2101c ◽

2013 ◽

Vol 24 (5) ◽

pp. 1606-1609 ◽

Cited By ~ 10

Author(s):

Safak Uygur ◽

Tolga Eryilmaz ◽

Onur Cukurluoglu ◽

Selahattin Ozmen ◽

Reha Yavuzer

Keyword(s):

Bone Defects ◽

Cranial Bone

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Reconstruction of Large Bone Defects and Complex Non-Unions Using a Free Fibular Bone Graft and a Supplementary Allograft

Zeitschrift für Orthopädie und Unfallchirurgie ◽

10.1055/a-1161-9566 ◽

2020 ◽

Author(s):

Selina Gaida ◽

Uwe Schweigkofler ◽

Wibke Moll ◽

Michael Sauerbier ◽

Reinhard Hoffmann

Keyword(s):

Bone Graft ◽

Case Series ◽

Bone Defects ◽

Bone Transplantation ◽

Patient Comfort ◽

Masquelet Technique ◽

Specialized Center ◽

Free Fibula ◽

Large Bone ◽

Large Bone Defects

AbstractLarge bone defects or complex pseudarthrosis represent an interdisciplinary challenge. Established surgical procedures include autogenous cancellous bone graft, the Masquelet technique or bone transfer via segment transport as well as free microvascular bone transplantation. However, the successful use of all these techniques requires a specialized center with great interdisciplinary expertise. In the following case series we describe the technique of free fibula transplantation and additional allograft. In both cases a good functional result with full mechanical strength of the affected extremity and satisfactory patient comfort has been achieved. In the second case, implant failure with the necessity of revision endoprosthetics occurred during the procedure.

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Biocomposite cryogels as tissue engineered biomaterials for regeneration of critical-sized cranial bone defects

Tissue Engineering Part A ◽

10.1089/ten.tea.2013.0072 ◽

2013 ◽

pp. 131022233639007 ◽

Cited By ~ 10

Author(s):

Ruchi Mishra ◽

S.K. Goel ◽

K.C. Gupta ◽

Ashok Kumar

Keyword(s):

Bone Defects ◽

Cranial Bone

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Combined Effect of Bone Morphogenetic Protein-2 and Erythropoietin on Regeneration of Cranial Bone Defects in Mice

Bulletin of Experimental Biology and Medicine ◽

10.1007/s10517-019-04538-5 ◽

2019 ◽

Vol 167 (3) ◽

pp. 408-412 ◽

Cited By ~ 4

Author(s):

A. V. Gromov ◽

M. S. Bartov ◽

P. A. Orlova ◽

V. N. Manskikh ◽

M. S. Krivozubov ◽

...

Keyword(s):

Bone Morphogenetic Protein ◽

Bone Defects ◽

Combined Effect ◽

Bone Morphogenetic Protein 2 ◽

Cranial Bone ◽

Morphogenetic Protein

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Cranioplasty for bone defects after craniosynostosis surgery. Case series with literature review

Neurochirurgie ◽

10.1016/j.neuchi.2019.10.015 ◽

2020 ◽

Vol 66 (2) ◽

pp. 97-101 ◽

Cited By ~ 1

Author(s):

A. Szathmari ◽

A. Morgado ◽

P.A. Beuriat ◽

P. Petrescu ◽

F. Di Rocco ◽

...

Keyword(s):

Literature Review ◽

Case Series ◽

Bone Defects

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Evaluation of the Long-Term Results of Rat Cranial Bone Repair Using a Particular Xenograft

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-09-00064 ◽

2010 ◽

Vol 36 (3) ◽

pp. 167-173 ◽

Cited By ~ 5

Author(s):

Hakan Develioglu ◽

SerpilÜnver Saraydın ◽

Ünal Kartal ◽

Levent Taner

Keyword(s):

Bone Formation ◽

Bone Repair ◽

Fibrous Tissue ◽

Bone Defects ◽

Parietal Bone ◽

Control Area ◽

Cranial Bone ◽

Long Term Results ◽

Tissue Samples ◽

Defect Sites

Abstract Bone defects that cannot be healed completely are termed critical-sized defects and can be used to test bone grafts for medicine, dentistry, and periodontology. The aim of the present study was to detect the effects of a xenograft (Unilab Surgibone) on bone building in experimentally created parietal bone defects in rats. Standardized parietal bone defects were created in 16 rats, and each defect had a circular morphology 6 mm in diameter. The right defect sites were filled with porous particle material, and the left site was used as control. After the 3rd, 6th, and 12th months, rats were killed and tissue samples obtained from the related site of the cranium. Subsequently, histological sections were taken and stained with different stains for evaluation under light microscope. The rate of bone formation was assessed using a semiquantitative method. These results showed that dense collagenous tissue was observed in the control area during the third month, whereas xenograft particles were surrounded by a fibrous tissue layer at the implantation site. Osteoclast-like cells were also observed. There was also no significant bone repair at other observation periods. It can be concluded that the material used had no evidence of resorption and does not enhance bone formation. However, it seems biocompatible, osteoconductive, and could be used in a limited manner as a material for filling osseous defects in clinical practice.

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