Repair of Cranial Bone Defects With Calcium Phosphate Ceramic Implant or Autogenous Bone Graft

2007 ◽  
Vol 18 (2) ◽  
pp. 281-286 ◽  
Author(s):  
Rosane Vieira da Silva ◽  
Celso Aparecido Bertran ◽  
Elizabete Yoshie Kawachi ◽  
Jos?? Angelo Camilli
Keyword(s):  
Calcium Phosphate ◽  
Bone Graft ◽  
Bone Defects ◽  
Cranial Bone ◽  
Autogenous Bone Graft ◽  
Autogenous Bone ◽  
Calcium Phosphate Ceramic ◽  
Ceramic Implant

scholarly journals Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study

2006 ◽  
Vol 21 (5) ◽  
pp. 341-347 ◽  
Author(s):  
José Carlos Garcia de Mendonça ◽  
Rafael De Rossi ◽  
Celso Massaschi Inouye ◽  
Diego Rodrigo Paulillo Bazan ◽  
João Carlos Castro Monteiro ◽  
...  
Keyword(s):  
Bone Graft ◽  
Castor Oil ◽  
Bone Repair ◽  
Bone Defects ◽  
Autogenous Bone Graft ◽  
Autogenous Bone ◽  
Control Group ◽  
Cell Nuclei ◽  
Zygomatic Bone ◽  
Chi Squared

PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.

scholarly journals Characterization of bone repair in rat femur after treatment with calcium phosphate cement and autogenous bone graft

2010 ◽  
Vol 6 (1) ◽  
Author(s):  
Edela Puricelli ◽  
Adriana Corsetti ◽  
Deise Ponzoni ◽  
Gustavo L. Martins ◽  
Mauro G. Leite ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Graft ◽  
Calcium Phosphate Cement ◽  
Bone Repair ◽  
Rat Femur ◽  
Autogenous Bone Graft ◽  
Autogenous Bone

Repair of Bone Defects Treated with Autogenous Bone Graft and Low-Power Laser

2006 ◽  
Vol 17 (2) ◽  
pp. 297-301 ◽  
Author(s):  
Rosane Vierra da Silva ◽  
Jos?? Angelo Camilli
Keyword(s):  
Low Power ◽  
Bone Graft ◽  
Bone Defects ◽  
Autogenous Bone Graft ◽  
Autogenous Bone ◽  
Power Laser

scholarly journals Evaluation of Amniotic-Derived Membrane Biomaterial as an Adjunct for Repair of Critical Sized Bone Defects

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Mikael Starecki ◽  
John A. Schwartz ◽  
Daniel A. Grande
Keyword(s):  
Bone Formation ◽  
Bone Graft ◽  
Critical Size ◽  
Bone Defects ◽  
Autogenous Bone Graft ◽  
Autogenous Bone ◽  
New Bone Formation ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Introduction. Autogenous bone graft is the gold standard in reconstruction of bone defects. The use of autogenous bone graft is problematic because of limited bone as well as donor site morbidity. This study evaluates a novel biomaterial as an alternative to autogenous bone graft. The biomaterial is amniotic membrane, rich in growth factors. Methods. Twenty-one adult male Sprague-Dawley rats were implanted with biomaterial using the rat critical size femoral gap model. After creation of the critical size femoral gap animals were randomized to one of the following groups: Group 1 (control): gap left empty and received no treatment; Group 2 (experimental): the gap was filled with commercially available bone graft; Group 3 (experimental): the gap was filled with bone graft plus NuCel amniotic tissue preparation. Results. The experimental groups demonstrated new bone formation compared to controls. The results were evident on radiographs and histology. Histology showed Group 1 controls to have 11.1% new bone formation, 37.8% for Group 2, and 49.2% for Group 3. These results were statistically significant. Conclusions. The study demonstrates that amniotic membrane products have potential to provide bridging of bone defects. Filling bone defects without harvesting autogenous bone would provide a significant improvement in patient care.

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