scholarly journals NIMG-71. DETECTION OF CYSTIC GLIOBLASTOMA FROM MAGNETIC RESONANCE IMAGING USING DEEP LEARNING TECHNIQUES

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi177-vi177
Author(s):  
Sara Ranjbar ◽  
Lee Curtin ◽  
Paula Whitmire ◽  
Leland Hu ◽  
Kristin Swanson
Keyword(s):  
Magnetic Resonance Imaging ◽  
Deep Learning ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Clinical Investigation ◽  
Class Imbalance ◽  
Training Data ◽  
Resonance Imaging ◽  
Large Patient ◽  
Cystic Component

Abstract Glioblastoma (GBM) is the most aggressive primary brain tumor with an average survival of 15 months with standard of care treatment. GBM patients typically present with necrosis surrounded by enhancement on T1-weighted post gadolinium magnetic resonance imaging (T1gd MRI), however some patients present with a significant cystic component. Cysts are caused by different underlying biological mechanisms to necrosis and are important to identify for future clinical investigations. These cystic components can be manually identified through MRI but this process can be time consuming for large patient cohorts. Over the last two decades, our lab has collected serial MRI data of brain tumor patients. With over 70,000 images now in the database and that number increasing daily, it is clear that we have a unique resource for clinical investigation and a need to automate this process. To this end, the aim of this work was to develop and assess the performance of a convolution neural network (CNN) model for automatic detection of cystic GBMs. In this retrospective IRB-approved work, we collected pretreatment MRIs of a patient cohort consisting of 85 patients with a significant cystic component at presentation along with 400 non-cystic GBM, both identified manually through MRI. Image slices with a view of the cystic component were used as positive samples for training. Data were randomly split into training, validation, and test sets using a 70:15:15 ratio. The proportion of positive to negative cases was comparable between sets. Prior to training, we used image augmentation techniques to compensate for the class imbalance in our data. Our results showed that deep learning networks can automatically detect cystic GBMs on MRIs with high accuracy and thus illustrates the potential use of this technique in clinically relevant settings.

scholarly journals Brain Tumor Classification using Deep Learning Algorithms

2021 ◽  
Vol 9 (12) ◽  
pp. 417-426
Author(s):  
Ankita Kadam
Keyword(s):  
Neural Network ◽  
Magnetic Resonance Imaging ◽  
Neural Networks ◽  
Deep Learning ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Brain Tumors ◽  
Tumor Classification ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Abstract: A Brain tumor is one aggressive disease. An estimated more than 84,000 people will receive a primary brain tumor diagnosis in 2021 and an estimated 18,600 people will die from a malignant brain tumor (brain cancer) in 2021.[8] The best technique to detect brain tumors is by using Magnetic Resonance Imaging (MRI). More than any other cancer, brain tumors can have lasting and life-altering physical, cognitive, and psychological impacts on a patient’s life and hence faster diagnosis and best treatment plan should be devised to improve the life expectancy and well-being of these patients. Neural networks have shown colossal accuracy in image classification and segmentation problems. In this paper, we propose comparative studies of various deep learning models based on different types of Neural Networks(ANN, CNN, TL) to firstly identify brain tumors and then classify them into Benign Tumor, Malignant Tumor or Pituitary Tumor. The data set used holds 3190 images on T1-weighted contrast-enhanced images which were cleaned and augmented. The best ANN model concluded with an accuracy of 78% and the best CNN model consisting of 3 convolution layers had an accuracy of 90%. The VGG16(retrained on the dataset) model surpasses other ANN, CNN, TL models for multi-class tumor classification. This proposed network achieves significantly better performance with a validation accuracy of 94% and an F1-Score of 91. Keywords: Artificial Neural Network(ANN), Convolution Neural Network (CNN), Transfer Learning(TL), Magnetic Resonance Imaging(MRI.)

scholarly journals Development of brain tumor segmentation of magnetic resonance imaging (MRI) using U-Net deep learning

2021 ◽  
Vol 4 (9(112)) ◽  
pp. 23-31
Author(s):  
Wasan M. Jwaid ◽  
Zainab Shaker Matar Al-Husseini ◽  
Ahmad H. Sabry
Keyword(s):  
Magnetic Resonance Imaging ◽  
Deep Learning ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Tumor Segmentation ◽  
Resonance Imaging ◽  
Brain Tumor Segmentation ◽  
Brain Images ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Brain tumors are the growth of abnormal cells or a mass in a brain. Numerous kinds of brain tumors were discovered, which need accurate and early detection techniques. Currently, most diagnosis and detection methods rely on the decision of neuro-specialists and radiologists to evaluate brain images, which may be time-consuming and cause human errors. This paper proposes a robust U-Net deep learning Convolutional Neural Network (CNN) model that can classify if the subject has a tumor or not based on Brain Magnetic resonance imaging (MRI) with acceptable accuracy for medical-grade application. The study built and trained the 3D U-Net CNN including encoding/decoding relationship architecture to perform the brain tumor segmentation because it requires fewer training images and provides more precise segmentation. The algorithm consists of three parts; the first part, the downsampling part, the bottleneck part, and the optimum part. The resultant semantic maps are inserted into the decoder fraction to obtain the full-resolution probability maps. The developed U-Net architecture has been applied on the MRI scan brain tumor segmentation dataset in MICCAI BraTS 2017. The results using Matlab-based toolbox indicate that the proposed architecture has been successfully evaluated and experienced for MRI datasets of brain tumor segmentation including 336 images as training data and 125 images for validation. This work demonstrated comparative performance and successful feasibility of implementing U-Net CNN architecture in an automated framework of brain tumor segmentations in Fluid-attenuated inversion recovery (FLAIR) MR Slices. The developed U-Net CNN model succeeded in performing the brain tumor segmentation task to classify the input brain images into a tumor or not based on the MRI dataset.

scholarly journals Deep learning model for glioma, meningioma and pituitary classification

2021 ◽  
Vol 10 (1) ◽  
pp. 88
Author(s):  
Toqa A. Sadoon ◽  
Mohammed H. Ali
Keyword(s):  
Magnetic Resonance Imaging ◽  
Deep Learning ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Common Causes ◽  
The Difference ◽  
Magnetic Resonance Imaging Mri ◽  
Confusion Matrices

<p>One of the common causes of death is a brain tumor. Because of the above mentioned, early detection of a brain tumor is critical for faster treatment, and therefore there are many techniques used to visualize a brain tumor. One of these techniques is magnetic resonance imaging (MRI). On the other hand, machine learning, deep learning, and convolutional neural network (CNN) are the state of art technologies in the recent years used in solving many medical image-related problems such as classification. In this research, three types of brain tumors were classified using magnetic resonance imaging namely glioma, meningioma, and pituitary gland on the based of CNN. The dataset used in this work includes 233 patients for a total of 3,064 contrast-enhanced T1 images. In this paper, a comparison is presented between the presented model and other models to demonstrate the superiority of our model over the others. Moreover, the difference in outcome between pre- and post-data preprocessing and augmentation was discussed. The highest accuracy metrics extracted from confusion matrices are; precision of 99.1% for pituitary, sensitivity of 98.7% for glioma, specificity of 99.1%, and accuracy of 99.1% for pituitary. The overall accuracy obtained is 96.1%.</p>

scholarly journals Deep Learning Approach in Brain Tumor Classification

2021 ◽  
pp. 246-250
Author(s):  
Bhavani Sankar A ◽  
Suryavarshini K
Keyword(s):  
Magnetic Resonance Imaging ◽  
Machine Learning ◽  
Deep Learning ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Current Trend ◽  
Ultrasound Image ◽  
Tumor Classification ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Various Computer-Aided Diagnosis (CAD) systems have been recently used in medical imaging to assist radiologist about their patients. Generally, various image technique such as Computer Tomography (CT), Magnetic Resonance Imaging (MRI) and ultrasound image are used to evaluate the tumor in a brain, lung, liver, breast, prostate etc., Especially, in this work MRI images are used to diagnose tumor in the brain. For full assistance of radiologists and better analysis of Magnetic Resonance Imaging, classification of brain tumor is essential procedure. The automatic classification scheme is essential to prevent the death rate of human. Deep learning is the newest and the current trend of machine learning field that paid a lot of the researchers’ attention in the recent few years. As a proven powerful machine learning tool, deep learning was widely used in several applications for solving various complex problems that require extremely high accuracy and sensitivity, particularly in the medical field. Tumor regions from an MR images are segmented using a deep learning technique. The automatic brain tumor classification is very challenging task in large spatial and structural variability of surrounding region of brain tumor. In this work, automatic brain tumor detection using Convolutional Neural Networks (CNN) classification. In general, brain tumor is one of the most common and aggressive malignant tumor diseases which is leading to very short expected life if it is diagnosed at higher grade. The deeper architecture design is performed by using small kernels. Other performance measures used in this study are the accuracy, sensitivity and specificity.

scholarly journals Differential Deep Convolutional Neural Network Model for Brain Tumor Classification

2021 ◽  
Vol 11 (3) ◽  
pp. 352
Author(s):  
Isselmou Abd El Kader ◽  
Guizhi Xu ◽  
Zhang Shuai ◽  
Sani Saminu ◽  
Imran Javaid ◽  
...  
Keyword(s):  
Neural Network ◽  
Magnetic Resonance Imaging ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Brain Tumors ◽  
Medical Image ◽  
Resonance Imaging ◽  
Feature Maps ◽  
Deep Cnn

The classification of brain tumors is a difficult task in the field of medical image analysis. Improving algorithms and machine learning technology helps radiologists to easily diagnose the tumor without surgical intervention. In recent years, deep learning techniques have made excellent progress in the field of medical image processing and analysis. However, there are many difficulties in classifying brain tumors using magnetic resonance imaging; first, the difficulty of brain structure and the intertwining of tissues in it; and secondly, the difficulty of classifying brain tumors due to the high density nature of the brain. We propose a differential deep convolutional neural network model (differential deep-CNN) to classify different types of brain tumor, including abnormal and normal magnetic resonance (MR) images. Using differential operators in the differential deep-CNN architecture, we derived the additional differential feature maps in the original CNN feature maps. The derivation process led to an improvement in the performance of the proposed approach in accordance with the results of the evaluation parameters used. The advantage of the differential deep-CNN model is an analysis of a pixel directional pattern of images using contrast calculations and its high ability to classify a large database of images with high accuracy and without technical problems. Therefore, the proposed approach gives an excellent overall performance. To test and train the performance of this model, we used a dataset consisting of 25,000 brain magnetic resonance imaging (MRI) images, which includes abnormal and normal images. The experimental results showed that the proposed model achieved an accuracy of 99.25%. This study demonstrates that the proposed differential deep-CNN model can be used to facilitate the automatic classification of brain tumors.

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