Viral Escape in the Central Nervous System with Multidrug-Resistant Human Immunodeficiency Virus-1
Keyword(s):
Abstract In this study, we report the case of a patient infected with human immunodeficiency virus (HIV)-1 who developed ataxia and neurocognitive impairment due to viral escape within the central nervous system (CNS) with a multidrug-resistant HIV-1 despite long-term viral suppression in plasma. Antiretroviral therapy optimization with drugs with high CNS penetration led to viral suppression in the CSF, regression of ataxia, and improvement of neurocognitive symptoms.
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1993 ◽
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1989 ◽
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2018 ◽
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