Emerging neuroimaging technologies: Toward future personalized diagnostics, prognosis, targeted intervention, and ethical challenges
The human brain is a fine-tuned and balanced structural, functional, and dynamic electrochemical system. Any alterations, from slight slowing of partial brain networks to severe disruptions in structural, functional, and dynamic connectivity across local and large-scale brain networks will result in slight to severe changes in cognitive ability, awareness, and consciousness. Using future noninvasive technologies, the common goal is to relate typical or atypical resting-state, sensory-motor functions, cognition, and consciousness to underlying typical or altered quantified brain structure, biochemistry, pathways, functional brain networks, and connectivity. This will pose enormous ethical challenges of quantitative diagnostic and prognostic strategies in future neurologic and psychiatric clinical practice.