Introduction

2021 ◽  
pp. 1-10
Author(s):  
Bernard Reginster

On the Genealogy of Morality stands out among Nietzsche’s works as his most cohesive and self-contained book. Each of its three essays is devoted to an explicitly stated topic, which it subjects to a fairly sustained and systematic treatment. The topics are unified insofar as they are the conceptual elements of a coherent outlook. And the essays devoted to them turn out to be linked in various ways: each draws on the findings of the others, while also shedding light on them. The contrast with Nietzsche’s other writings is striking, and fuels the expectation that a clearly delineated, well worked-out critical analysis of morality can be found in the book. Moreover, the book makes some arresting claims about morality: most prominently, that its invention is an act of revenge....

Author(s):  
Marsal Sanches ◽  
Rodrigo Machado-Vieira ◽  
Jair C. Soares

This chapter comprises a critical analysis of the main papers addressing the treatment of mood disorders (depressive disorder and bipolar disorder) from a historical standpoint. It begins with the first paper, authored by John Cade in the late 1940s, describing the use of lithium salts in the treatment of mania. Subsequently, it takes the reader on a journey over the antidepressant discovery process, starting with imipramine in the 1950s until the advent of fluoxetine in the 1970s and its ultimate incorporation into the therapeutic arsenal in the 1980s. It later approaches one of the first studies on the effectiveness of valproic acid for the management of bipolar disorder, in the early 1990s. Finally, the importance of ‘real-life’ studies of efficacy for the treatment of mood disorders is addressed, with a discussion of the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) and the Sequenced Treatment Alternatives to Relieve Depression (STAR*D).


Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A97-A97
Author(s):  
Hoy We ◽  
Baker P ◽  
Wang Z ◽  
Cass A ◽  
Mathews Jd ◽  
...  

2007 ◽  
Vol 177 (4S) ◽  
pp. 126-126
Author(s):  
Matthew E. Nielsen ◽  
Danil V. Makarov ◽  
Elizabeth B. Humphreys ◽  
Leslie A. Mangold ◽  
Alan W. Partin ◽  
...  

2020 ◽  
Vol 25 (1) ◽  
pp. 1-15 ◽  
Author(s):  
Amaia Del Campo ◽  
Marisalva Fávero

Abstract. During the last decades, several studies have been conducted on the effectiveness of sexual abuse prevention programs implemented in different countries. In this article, we present a review of 70 studies (1981–2017) evaluating prevention programs, conducted mostly in the United States and Canada, although with a considerable presence also in other countries, such as New Zealand and the United Kingdom. The results of these studies, in general, are very promising and encourage us to continue this type of intervention, almost unanimously confirming its effectiveness. Prevention programs encourage children and adolescents to report the abuse experienced and they may help to reduce the trauma of sexual abuse if there are victims among the participants. We also found that some evaluations have not considered the possible negative effects of this type of programs in the event that they are applied inappropriately. Finally, we present some methodological considerations as critical analysis to this type of evaluations.


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