Stereoselective C-O Ring Construction: (+)-Pachastrissamine (Fujii/Ohno), Aspalathin (Minehan), (+)-Varitriol (Ghosh), Aspercyclide A (Spivey), Etnangien (Menche)

2013 ◽  
Author(s):  
Douglass F. Taber
Keyword(s):  
California State University ◽  
Imperial College ◽  
Indian Institute ◽  
State University ◽  
Heck Coupling ◽  
Lead Compounds ◽  
Heck Cyclization ◽  
Aryl Glycosides ◽  
Jaspine B ◽  
Dependent Pathway

(+)-Pachastrissamine 3, also known as jaspine B, induces apoptosis in melanoma cells by a caspase-dependent pathway. Nobutaka Fujii and Hiroaki Ohno of Kyoyo University developed (J. Org. Chem. 2010, 75, 3831) a practical route to 3 based on the Pd-mediated cyclization of 1 to 2. Thomas G. Minehan of California State University, Northridge, optimized (Organic Lett. 2010, 12, 1580) the condensation of 5 with the bis-pivalate 4. This opened a general route to C-aryl glycosides, including aspalathin 6. (+)-Varitriol 11 is vinylogously related to 7. A key step in the synthesis of 11 reported (J. Org. Chem. 2010, 75, 2107) by Subhash Ghosh of the Indian Institute of Chemical Technology was the intermolecular Heck coupling of 8 with 9. Aspercyclide A 14 and its more stable methyl ether are promising lead compounds for the treatment of asthma. In the course of a synthesis of 14, Alan C. Spivey of Imperial College developed (Chem. Commun. 2010, 1824) the intramolecular Heck cyclization of 12 to 13. In a bold synthesis of etnangien 17, Dirk Menche of Ruprecht-Karls-Universität Heidelberg showed (J. Org. Chem. 2010, 75, 2429) that the intramolecular Heck coupling of 15 to 16 proceeded efficiently. The substituents on 15 may be favoring conformations that lead to cyclization.

Epic Cruelty: On Post-Pandemic Performance

2021 ◽  
Vol 37 (2) ◽  
pp. 119-136
Author(s):  
Rick Mitchell
Keyword(s):  
Climate Change ◽  
United States ◽  
African Americans ◽  
The United States ◽  
California State University ◽  
The State ◽  
State University ◽  
White Supremacist ◽  
Systemic Racism ◽  
Disaster Capitalism

As today’s catastrophic Covid-19 pandemic exacerbates ongoing crises, including systemic racism, rising ethno-nationalism, and fossil-fuelled climate change, the neoliberal world that we inhabit is becoming increasingly hostile, particularly for the most vulnerable. Even in the United States, as armed white-supremacist, pro-Trump forces face off against protesters seeking justice for African Americans, the hostility is increasingly palpable, and often frightening. Yet as millions of Black Lives Matter protesters demonstrated after the brutal police killing of George Floyd, the current, intersecting crises – worsened by Trump’s criminalization of anti-racism protesters and his dismissal of science – demand a serious, engaged, response from activists as well as artists. The title of this article is meant to evoke not only the state of the unusually cruel moment through which we are living, but also the very different approaches to performance of both Brecht and Artaud, whose ideas, along with those of others – including Benjamin, Butler, Latour, Mbembe, and Césaire – inform the radical, open-ended, post-pandemic theatre practice proposed in this essay. A critically acclaimed dramatist as well as Professor of English and Playwriting at California State University, Northridge, Mitchell’s published volumes of plays include Disaster Capitalism; or Money Can’t Buy You Love: Three Plays; Brecht in L.A.; and Ventriloquist: Two Plays and Ventriloquial Miscellany. He is the editor of Experimental O’Neill, and is currently at work on a series of post-pandemic plays.

scholarly journals California State University

1986 ◽  
Vol 70 (493) ◽  
pp. 71-73
Author(s):  
Walter F. Beckman
Keyword(s):  
California State University ◽  
State University

Fullerton Virtual Twin Study

2006 ◽  
Vol 9 (6) ◽  
pp. 963-964 ◽  
Author(s):  
Nancy L. Segal
Keyword(s):  
San Francisco ◽  
Social Relations ◽  
California State University ◽  
Future Research ◽  
State University ◽  
Collaborative Project ◽  
Similarities And Differences ◽  
Current Sample ◽  
The University ◽  
Mz Twins

AbstractVirtual twins (VTs; same-age unrelated siblings reared together from early infancy) have been studied at California State University (CSU), Fullerton since 1991. The current sample includes over 130 pairs. Past and current research have research have focused on siblings' similarities and differences in general intelligence and body size. Future research in these areas will continue as new pairs continue to be identified. These studies will be supplemented by analyses of personality, social relations and adjustment using monozygotic (MZ) twins, dizygotic (DZ) twins, full siblings and friends, as well as new VTs, who have participated in Twins, Adoptees, Peers and Siblings (TAPS), a collaborative project conducted between CSU Fullerton and the University of San Francisco, from 2002 to 2006.

scholarly journals Leading with Justice: Afterword and Next Steps

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Editorial Board
Keyword(s):  
School Districts ◽  
Cross Section ◽  
Research Policy ◽  
Doctoral Program ◽  
Spoken Word ◽  
California State University ◽  
Virtual Space ◽  
State University ◽  
Policy And Practice ◽  
Community Groups

   The term justice has become a catchphrase in education, used often and yet still evasive. In an attempt to define justice in research, policy, and practice, the California State University, Sacramento Doctoral Program in Educational Leadership invited preeminent scholars into the conversation through a public webinar series. Hundreds of people tuned in to listen and learn—some sessions having over 350 active participants. The attendees represented a unique cross-section of stakeholders: about 1/3 from universities, 1/3 from school districts, and 1/3 from community groups. Each webinar began and closed with music (e.g., Ain’t No Stoppin’ Us Now) that curated and uplifted the virtual space. Local spoken word artists were also invited 

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