THE RELATIONSHIP OF HEPATITIS B SURFACE ANTIGEN AND ANTIBODY TO ATOMIC BOMB RADIATION IN THE ADULT HEALTH STUDY SAMPLE, 1975–1977

1983 ◽  
Vol 117 (5) ◽  
pp. 610-620 ◽  
Author(s):  
HIROO KATO ◽  
MAKOTO MAYUMI ◽  
KUSUYA NISHIOKA ◽  
HOWARD B. HAMILTON
1978 ◽  
Vol 138 (2) ◽  
pp. 252-256 ◽  
Author(s):  
N. Nath ◽  
C. T. Fang ◽  
R. Ledman ◽  
S. Mazzur ◽  
R. Y. Dodd

1980 ◽  
Vol 28 (2) ◽  
pp. 459-463
Author(s):  
J W Shih ◽  
P L Tan ◽  
J L Gerin

A significant proportion (20 to 40%) of highly purified 22-nm hepatitis B surface antigen (HBsAg) particles contain human serum albumin (HSA) as demonstrated by specific precipitation of radioiodinated particles by anti-HSA. Preparations of the isolated major HBsAg polypeptides (P-1, P-2, and P-6) were iodinated and analyzed by radiommunoprecipitation for reactivity with rabbit antisera to human plasma proteins. Only the P-6 fraction (molecular weight, 68,000) was precipitated and only by anti-HSA; specific precipitation was observed with guinea pig antisera to P-6 and native HBsAg and goat or rabbit antisera to HSA. Coprecipitation of P-6 with antiserum to HBsAg and with anti-HSA, compared to precipitation with each antiserum alone, indicated that the HBsAg and HSA determinants were on separate molecules. The P-6 polypeptide may represent a precursor protein of the hepatitis B virion.


1980 ◽  
Vol 48 (2) ◽  
pp. 273-283 ◽  
Author(s):  
Y. Sanchez ◽  
I. Ionescu-Matiu ◽  
F. B. Hollinger ◽  
J. L. Melnick ◽  
G. R. Dreesman

2022 ◽  
Vol 33 (1) ◽  
pp. 62-67
Author(s):  
Qiangwei Shi ◽  
◽  
Rui Yu ◽  
Qian Sun ◽  
Chunfeng Wang ◽  
...  

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