scholarly journals Corrigendum to: Redox in Magmas: Comment on a Recent Treatment of the Kaiserstuhl Volcanics (Braunger et al., Journal of Petrology, 59, 1731–1762, 2018) and Some Other Misconceptions

2021 ◽  
Vol 62 (5) ◽  
Author(s):  
Michael Anenburg ◽  
Hugh St C O‘Neill
Keyword(s):  
Author(s):  
Hai-Jun Hu ◽  
Xiu Liang ◽  
Hai-Lang Li ◽  
Huai-Yuan Wang ◽  
Jin-Fa Gu ◽  
...  

AbstractAlthough the recent treatment in melanoma through the use of anti-PD-1 immunotherapy is successful, the efficacy of this approach remains to be improved. Here, we explore the feasibility of combination strategy with the armed oncolytic adenovirus ZD55-IL-24 and PD-1 blockade. We find that combination therapy with localized ZD55-IL-24 and systemic PD-1 blockade leads to synergistic inhibition of both local and distant established tumors in B16-bearing immunocompetent mouse model. Our further mechanism investigation reveals that synergistic therapeutic effect is associated with marked promotion of tumor immune infiltration and recognition in both local and distant tumors as well as spleens. PD-1 blockade has no obvious effect on promotion of tumor immune infiltration and recognition. Localized therapy with ZD55-IL-24, however, can help PD-1 blockade to overcome the limitation of relatively low tumor immune infiltration and recognition. This study provides a rationale for investigation of such combination therapy in the clinic.


2019 ◽  
Vol 62 (4) ◽  
pp. 218
Author(s):  
Young Joo Shin
Keyword(s):  
Dry Eye ◽  

2019 ◽  
Vol 12 (10) ◽  
pp. e231899
Author(s):  
Yinglun Wu ◽  
Philip C Dittmar

Rheumatoid arthritis (RA) is a common connective tissue disorder affecting the synovial joints. In patients with RA, involvement of the lungs occurs in 30%–40% of cases while pleural effusions occur in only 3%–5%. However, the majority of RA-associated pleural effusions are small, unilateral and asymptomatic. We present a case of massive bilateral pleural effusions in a patient with established rheumatoid pneumoconiosis (Caplan syndrome). Interestingly, the pleural effusion occurred following recent treatment for minimal change disease and atrial fibrillation.


2021 ◽  
pp. 0734242X2110667
Author(s):  
Valentina Grossule ◽  
Ding Fang ◽  
Dongbei Yue ◽  
Maria Cristina Lavagnolo ◽  
Roberto Raga

When approaching the study of new processes for leachate treatment, each influencing variable should be kept under control to better comprehend the treatment process. However, leachate quality is difficult to control as it varies dramatically from one landfill to another, and in line with landfill ageing. To overcome this problem, the present study investigated the option of preparing a reliable artificial leachate in terms of quality consistency and representativeness in simulating the composition of real municipal solid waste (MSW) leachate, in view of further investigate the recent treatment process using black soldier fly (BSF) larvae. Two recipes were used to simulate a real leachate (RL): one including chemical ingredients alone (artificial synthetic leachate-SL), and the other including chemicals mixed with artificial food waste (FW) eluate (artificial mixed leachate-ML). Research data were analysed, elaborated and discussed to assess simulation performance according to a series of parameters, such as Analytical representativeness, Treatment representativeness (in this case specific for the BSF larvae process), Recipe relevance, Repeatability and Flexibility in selectively modifying individual quality parameters. The best leachate simulation performance was achieved by the synthetic leachate, with concentration values generally ranging between 97% and 118% of the RL values. When feeding larvae with both RL and SL, similar mortality values and growth performance were observed.


2020 ◽  
Vol 7 (-3) ◽  
pp. 242
Author(s):  
Christopher P. Denton ◽  
◽  
Philip Yee ◽  
Voon H. Ong ◽  
◽  
...  

2015 ◽  
Vol 104 (Suppl) ◽  
pp. 120b-120b
Author(s):  
Masakatsu Motomura

1994 ◽  
pp. 491-492 ◽  
Author(s):  
H. Inamura ◽  
M. Aoyagi ◽  
H. Tojima ◽  
H. Maeyama ◽  
Y. Koike

2019 ◽  
Vol 60 (4) ◽  
pp. 453-473
Author(s):  
Carol S. Aneshensel ◽  
Jenna van Draanen ◽  
Helene Riess ◽  
Alice P. Villatoro

Based on the premise that treatment changes people in ways that are consequential for subsequent treatment-seeking, we question the validity of an unrecognized and apparently inadvertent assumption in mental health services research conducted within a psychiatric epidemiology paradigm. This homogeneity assumption statistically constrains the effects of potential determinants of recent treatment to be identical for former patients and previously untreated persons by omitting treatment history or modeling only main effects. We test this assumption with data from the 2001–2003 Collaborative Psychiatric Epidemiology Surveys; the weighted pooled sample is representative of noninstitutionalized U.S. adults (18+; analytic n = 19,227). Contrary to the homogeneity assumption, some associations with recent treatment are conditional on past treatment, including psychiatric disorder and race-ethnicity—measures of need and treatment disparities, respectively. We conclude that the widespread application of the homogeneity assumption probably masks differences in the determinants of recent use between previously untreated persons and former patients.


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