Physical Activity, Sedentary Behavior, And Skeletal Muscle Strength In Patients With Chronic Kidney Disease: An Isotemporal Substitution Approach

2021 ◽  
Author(s):  
Masaki Yoshioka ◽  
Keisei Kosaki ◽  
Masahiro Matsui ◽  
Kanako Takahashi ◽  
Ai Shibata ◽  
...  
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Muscle Strength ◽  
Sedentary Behavior ◽  
Knee Extension ◽  
Chair Stand ◽  
Knee Extension Strength ◽  
Isometric Knee Extension ◽  
Intensity Physical Activity ◽  
Skeletal Muscle Strength

Abstract Objective Insufficient physical activity and excessive sedentary behavior can contribute to decreased skeletal muscle strength, which is strongly associated with increased mortality in patients with chronic kidney disease (CKD). However, the potential impact of replacing sedentary behavior with physical activity on skeletal muscle strength remains unclear in these patients. The purpose of this study was to examine the associations of physical activity, sedentary behavior, and skeletal muscle strength in patients with CKD using an isotemporal substitution model to estimate the associations on replacing time from one behavior to another while keeping the total time and other behaviors fixed. Methods A total of 108 patients with CKD (mean age = 65 [SD = 9] y; mean estimated glomerular filtration rate = 57 [SD = 22] mL/min/1.73m2) participated in this cross-sectional analysis study. The time spent in sedentary behavior, light-intensity physical activity, and moderate- to vigorous-intensity physical activity (MVPA) were assessed using a triaxial accelerometer. Handgrip strength, isometric knee extension strength, and 30-second chair stand test were used to measure skeletal muscle strength. Results In multivariate analyses (single-factor and partition models), the time spent in MVPA was beneficially associated with both isometric knee extension strength and 30-second chair stand test. Furthermore, the isotemporal substitution model found that replacing 10 minutes per day of sedentary behavior or light-intensity physical activity with equivalent MVPA time was beneficially associated with both isometric knee extension strength and 30-second chair stand test. Conclusions Our cross-sectional findings indicate that MVPA time is beneficially associated with lower extremity muscle strength and that a slight increase in the MVPA time may contribute to maintaining skeletal muscle strength in patients with CKD. Impact Increasing the time spent in MVPA (10 min/day) may be a feasible strategy in patients with CKD, who have a high prevalence of impaired physical function.

scholarly journals Effect of acute exacerbations on skeletal muscle strength and physical activity in cystic fibrosis

2012 ◽  
Vol 11 (3) ◽  
pp. 209-215 ◽  
Author(s):  
Jason Wieboldt ◽  
Louis Atallah ◽  
Julia L. Kelly ◽  
Dinesh Shrikrishna ◽  
Khin M. Gyi ◽  
...  
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Cystic Fibrosis ◽  
Muscle Strength ◽  
Acute Exacerbations ◽  
Skeletal Muscle Strength

Identification of phenotypes in COPD patients: influence of physical activity in daily life, body composition and skeletal muscle strength

2017 ◽  
Author(s):  
Rafaella Xavier ◽  
Aline Lopes ◽  
Ana Carolina Pereira ◽  
Regina Maria Carvalho Pinto ◽  
Alberto Cukier ◽  
...  
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Body Composition ◽  
Muscle Strength ◽  
Daily Life ◽  
Copd Patients ◽  
Skeletal Muscle Strength

Comparison of single- or multifrequency bioelectrical impedance analysis and spectroscopy for assessment of appendicular skeletal muscle in the elderly

2013 ◽  
Vol 115 (6) ◽  
pp. 812-818 ◽  
Author(s):  
Yosuke Yamada ◽  
Yuya Watanabe ◽  
Masahiro Ikenaga ◽  
Keiichi Yokoyama ◽  
Tsukasa Yoshida ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Strength ◽  
Bioelectrical Impedance Analysis ◽  
Correlation Coefficients ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
The Elderly ◽  
Knee Extension ◽  
Appendicular Skeletal Muscle ◽  
Skeletal Muscle Strength

Bioelectrical impedance analysis (BIA) is used to assess skeletal muscle mass, although its application in the elderly has not been fully established. Several BIA modalities are available: single-frequency BIA (SFBIA), multifrequency BIA (MFBIA), and bioelectrical impedance spectroscopy (BIS). The aim of this study was to examine the difference between SFBIA, MFBIA, and BIS for assessment of appendicular skeletal muscle strength in the elderly. A total of 405 elderly (74.2 ± 5.0 yr) individuals were recruited. Grip strength and isometric knee extension strength were measured. Segmental SFBIA, MFBIA, and BIS were measured for the arms and upper legs. Bioelectrical impedance indexes were calculated by squared segment length divided by impedance ( L2/Z). Impedance at 5 and 50 kHz (Z5 and Z50) was used for SFBIA. Impedance of the intracellular component was calculated from MFBIA (Z250-5) and BIS (RICW). Correlation coefficients between knee extension strength and L2/Z5, L2/Z50, L2/RICW, and L2/Z250-5 of the upper legs were 0.661, 0.705, 0.790, and 0.808, respectively ( P < 0.001). Correlation coefficients were significantly greater for MFBIA and BIS than SFBIA. Receiver operating characteristic curves showed that L2/Z250-5 and L2/RICW had significantly larger areas under the curve for the diagnosis of muscle weakness compared with L2/Z5 and L2/Z50. Very similar results were observed for grip strength. Our findings suggest that MFBIA and BIS are better methods than SFBIA for assessing skeletal muscle strength in the elderly.

Identification of Phenotypes in People with COPD: Influence of Physical Activity, Sedentary Behaviour, Body Composition and Skeletal Muscle Strength

Lung ◽  
2018 ◽  
Vol 197 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Rafaella F. Xavier ◽  
Ana Carolina A. C. Pereira ◽  
Aline C. Lopes ◽  
Vinícius Cavalheri ◽  
Regina M. C. Pinto ◽  
...  
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Body Composition ◽  
Muscle Strength ◽  
Sedentary Behaviour ◽  
Skeletal Muscle Strength

scholarly journals The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study

2017 ◽  
Vol 92 (5) ◽  
pp. 710-718 ◽  
Author(s):  
Trine Karlsen ◽  
Javaid Nauman ◽  
Håvard Dalen ◽  
Arnulf Langhammer ◽  
Ulrik Wisløff
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Muscle Strength ◽  
Older Women ◽  
Skeletal Muscle Strength

scholarly journals Impaired knee extension muscle strength in adolescents but not in children with Fontan circulation

2020 ◽  
Vol 30 (8) ◽  
pp. 1138-1143
Author(s):  
Camilla Sandberg ◽  
Emelie Frisk ◽  
Lena Hansson ◽  
Annika Isberg ◽  
Eva Rylander Hedlund ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Lean Mass ◽  
Plantar Flexion ◽  
Knee Extension ◽  
Fontan Circulation ◽  
Group Level ◽  
Cross Sectional ◽  
Knee Extension Strength ◽  
Isometric Knee Extension ◽  
Isometric Muscle

AbstractIntroduction:Impaired isometric muscle strength was previously reported in adults with Fontan circulation. However, it is unclear if this impairment is present in children and adolescents with Fontan circulation. We investigated isometric muscle strength of the lower limb in patients (6–18 years) with Fontan circulation in comparison with healthy controls.Method:In this cross-sectional study, 43 patients (6–18 years) with Fontan circulation and 43 age- and sex-matched controls were included. Isometric knee extension and plantar flexion muscle strength were assessed using dynamometry (Newton, N). Lean mass of the legs was assessed with dual-energy X-ray absorptiometry. Analyses were performed on group level (n = 43), and for subgroups that included children aged 6–12 years (n = 18) and adolescents aged 13–18 years (n = 25).Results:On group level, the patients with Fontan circulation had impaired isometric knee extension strength in comparison with the controls (p = 0.03). In subgroup analyses, impaired isometric knee extension strength was present in the adolescents (p = 0.009) but not in the children groups. For plantar flexion, there was no difference between patients and controls. There was no difference in lean mass between patients and controls (9.6 ± 4.3 kg vs. 10.8 ± 5.6 kg, p = 0.31). However, the lean mass was highly correlated to isometric knee extension strength (patients r = 0.89, controls r = 0.96, p < 0.001) and isometric plantar flexion strength (patients r = 0.7, controls r = 0.81, p < 0.001).Conclusion:The finding of impaired isometric knee extension muscle strength in adolescents (13–18 years) with Fontan circulation and no corresponding impairment in the children group (6–12 years) could imply that isometric muscle strength gets more impaired with age.

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