scholarly journals 0742 Hypersomnia Severity Index: Reliability and Validity in a Behavioral Sleep Medicine Clinical Sample

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A282-A282
Author(s):  
G Amatrudo ◽  
K Puzino ◽  
E Bourchetin ◽  
S L Calhoun ◽  
J Fernandez-Mendoza
Keyword(s):  
Sleep Disorders ◽  
Convergent Validity ◽  
Reliability And Validity ◽  
Severity Index ◽  
Sleep Medicine ◽  
Criterion Validity ◽  
Treatment Center ◽  
Clinical Samples ◽  
Patient Reported ◽  
Penn State

Abstract Introduction There is a need for patient-reported outcome measures of central disorders of hypersomnolence (CDH) that adequately assess both essential features and associated daytime impact. The Hypersomnia Severity Index (HSI) was designed to assess severity, distress and impairment of hypersomnolence in persons with psychiatric disorders. Little data is available regarding its psychometric properties in clinical samples with diverse sleep disorders, including CDH. Methods 158 consecutive patients (44.11±16.38 years old, 70.9% female, 19.6% minority) who were evaluated at the Behavioral Sleep Medicine (BSM) program of Penn State Hershey Sleep Research & Treatment Center completed the HSI and the Epworth Sleepiness Scale (ESS). All patients were diagnosed using ICSD-3 criteria, with 10 % receiving a diagnosis of CDH, 54% of insomnia disorder (ID) and 36% of other sleep disorders (oSD). Results The HSI showed satisfactory internal consistency (Cronbach’s α=0.79) and item-total correlations (r=0.42-0.67), except for item 1 (r=0.17). Principal component analysis provided a 2-factor structure (HSI-Symptoms and HSI-Impact) explaining 56.20% of the variance. Convergent validity with ESS was optimal (r=0.65) but greater for HSI-Symptoms (r=0.69) than HSI-Impact (r=0.39). Criterion validity showed significantly higher scores in subjects with CDH (22.63±7.57) and significantly lower scores in subjects with ID (16.96±5.96) as compared to those with oSD (18.65±6.65); however, these divergent scores were primarily driven by the HSI-Symptoms score (p<0.01) rather than the HSI-Impact score (p>0.12). Conclusion The HSI shows satisfactory indices of reliability and validity in a clinically-diverse sleep disorders sample. Its criterion validity is supported by its divergent association with insomnia vs. hypersomnia disorders. Future studies should examine cut-off score for the HSI to reliably identify CDH and test its sensitivity to treatment effects. Support Department of Psychiatry, Penn State College of Medicine

512 Confirmatory Factor Analysis of the Sleep Inertia Questionnaire in a Clinical Sample with Sleep Disorders

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A201-A202
Author(s):  
Kristina Puzino ◽  
Susan Calhoun ◽  
Allison Harvey ◽  
Julio Fernandez-Mendoza
Keyword(s):  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Construct Validity ◽  
Sleep Disorders ◽  
Goodness Of Fit ◽  
Criterion Validity ◽  
Clinical Samples ◽  
Sleep Inertia ◽  
Confirmatory Factor ◽  
Sensitivity Specificity

Abstract Introduction The Sleep Inertia Questionnaire (SIQ) was developed and validated in patients with mood disorders to evaluate difficulties with becoming fully awake after nighttime sleep or daytime naps in a multidimensional manner. However, few data are available regarding its psychometric properties in clinical samples with sleep disorders. Methods 211 patients (43.0±16.4 years old, 68% female, 17% minority) evaluated at the Behavioral Sleep Medicine (BSM) program of Penn State Health Sleep Research & Treatment Center completed the SIQ. All patients were diagnosed using ICSD-3 criteria, with 111 receiving a diagnosis of chronic insomnia disorder (CID), 48 of a central disorder of hypersomnolence (CDH), and 52 of other sleep disorders (OSD). Structural equation modelling was used to conduct confirmatory factor analysis (CFA) of the SIQ. Results CFA supported four SIQ dimensions of “physiological”, “cognitive”, “emotional” and “response to” (RSI) sleep inertia with adequate goodness-of-fit (TLI=0.90, CFI=0.91, GFI=0.85, RMSEA=0.08). Internal consistency was high (α=0.94), including that of its dimensions (physiological α=0.89, cognitive α=0.94, emotional α=0.67, RSI α=0.78). Dimension inter-correlations were moderate to high (r=0.42–0.93, p<0.01), indicating good construct validity. Convergent validity showed moderate correlations with Epworth sleepiness scale (ESS) scores (r=0.38) and large correlations with Flinders fatigue scale (FFS) scores (r=0.65). Criterion validity showed significantly (p<0.01) higher scores in subjects with CDH (69.0±16.6) as compared to those with CID (54.4±18.3) or OSD (58.5±20.0). A SIQ cut-off score ≥57.5 provided a sensitivity/specificity of 0.77/0.65, while a cut-off score ≥61.5 provided a sensitivity/specificity of 0.71/0.70 to identify CDH vs. ESS<10 (AUC=0.76). Conclusion The SIQ shows satisfactory indices of reliability and construct validity in a clinically-diverse sleep disorders sample. Its criterion validity is supported by its divergent association with hypersomnia vs. insomnia disorders, as well as its adequate sensitivity/specificity to identify patients with CDH. The SIQ can help clinicians easily assess the complex dimensionality of sleep inertia and target behavioral sleep treatments. Future studies should confirm the best SIQ cut-off score by including good sleeping controls, while clinical studies should determine its minimal clinically important difference after pharmacological or behavioral treatments. Support (if any):

scholarly journals NCOG-70. RELIABILITY AND VALIDITY OF A NEW SELF-REPORT INDEX OF COGNITIVE CONCERNS IN BRAIN TUMOR PATIENTS

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii145-ii145
Author(s):  
Giuliana Zarrella ◽  
Alice Perez ◽  
Jorg Dietrich ◽  
Michael Parsons
Keyword(s):  
Brain Tumor ◽  
Verbal Memory ◽  
Cognitive Abilities ◽  
Convergent Validity ◽  
Discriminant Validity ◽  
Reliability And Validity ◽  
Cognitive Testing ◽  
Self Report ◽  
Measurement Information ◽  
Patient Reported

Abstract INTRODUCTION Subjective cognitive dysfunction is an important outcome measure in neuro-oncology and may provide additional information beyond performance-based neuropsychological testing. The Functional Assessment of Cancer Therapy-Brain (FACT-Br) is a frequently used quality of life (QoL) measure that includes indices of physical, emotional, social, and neurologic aspects of disease, but does not measure cognitive concerns. This study seeks to develop and validate an index of self-reported cognition derived from existing items on the FACT-Br. METHODS 145 patients (Mage=51.08, Medu=15.63) with heterogeneous brain tumor diagnoses completed neuropsychological evaluation including cognitive testing and self-report measures. Nine FACT-Br items regarding cognition were combined to form the Cognitive Index (CI). Reliability of the CI was measured with Cronbach’s alpha. Concurrent validity was assessed by correlating the CI with the Patient-Reported Outcomes Measurement Information System (PROMIS) Cognitive Abilities-8 or PROMIS Cognitive Concerns-8. Discriminant validity was assessed by correlation of the CI with other FACT-Br indices and the Beck Depression and Anxiety Inventories (BDI, BAI). RESULTS Internal consistency within the CI was high (Cronbach’s a 0.864). The CI correlated strongly with the PROMIS-Abilities (r =.680; p< 0.001) and PROMIS-Concerns (r=.780; p< 0.001) indicating high convergent validity. Moderate correlations were observed between the CI and the physical and functional subscales of the FACT (r=.453 and .555), whereas correlations with the social and emotional functioning subscales were weaker (r=.381 and .325). The FACT-Br-CI correlated strongly with BDI (r=-.622) and more weakly with the BAI (r=-.344). Consistent with prior literature, the CI showed modest correlations with neuropsychological measures, including verbal memory encoding (r=.300), verbal fluency (r=.252) and a composite measure of cognition (r=.249; all p’s< .01). CONCLUSIONS The FACT-Br-CI is a reliable and valid measure of self-reported cognition. Studies that include the FACT-Br could be retrospectively analyzed to assess self-reported cognitive outcomes, enriching the information gained from prior research.

scholarly journals 1107 Arousal And Sleepiness In Opioid Use Disorder Compared To Insomnia Disorder With And Without Comorbid Psychiatric Conditions

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A421-A421
Author(s):  
V B Krishnamurthy ◽  
N Hussain ◽  
K Puzino ◽  
S Yadav ◽  
S Del Tredici ◽  
...  
Keyword(s):  
Development Program ◽  
Severity Index ◽  
Opioid Use Disorder ◽  
Treatment Center ◽  
Opioid Use ◽  
Faculty Development Program ◽  
Specific Patient ◽  
Insomnia Disorder ◽  
Penn State ◽  
Psychiatric Conditions

Abstract Introduction Insomnia is frequent in opioid use disorder patients on buprenorphine (OUDB) and increases risk of relapse. There is lack of data evaluating specific differences in hyperarousal and daytime sequelae between OUDBs as compared to individuals with insomnia disorder without (ID) or with comorbid psychiatric conditions (CID). Methods We studied 112 patients with ID (47.8±16.3y, 55% female, 13% minority) and 148 with CID (44.7±15.6y, 69% female, 16% minority) evaluated at the Behavioral Sleep Medicine program of Penn State Hershey Sleep Research & Treatment Center and 71 OUDB (37.8±11.2y, 51% female, 16% minority) evaluated at the Recovery, Advocacy, Empowerment and Service program and WellSpan Internal Medicine clinics (York, PA). Subjects completed the Insomnia Severity Index (ISI), Ford Insomnia Response to Stress (FIRST), Arousal Predisposition Scale (APS), Pre-sleep Arousal cognitive (PSAS-C) and somatic (PSAS-S) Scale, Dysfunctional Beliefs and Attitudes about Sleep Scale (DBAS) and Epworth Sleepiness Scale (ESS). Excessive daytime sleepiness (EDS) was defined as an ESS score ≥ 10. MANCOVA included age, sex, race/ethnicity and depression as covariates, while logistic regression further included ISI, APS and PSAS-S. Results No differences across groups were observed in PSAS-C or DBAS scores. Subjects with CID and OUDB had significantly higher PSAS-S (15.7±0.5 and 16.4±0.7, respectively) and APS (35.6±0.6 and 36±1, respectively) scores as compared to the ID group (14.2±0.6 and 33.2±0.7, respectively). Subjects with OUDB had significantly higher ESS score (9.8±0.6) as compared to the ID or CID groups (6.2±0.5 and 6.4±0.4, respectively). The odds of EDS were 2.7 times (95%CI=1.2-6.1) higher in the OUDB group as compared to the ID group. Conclusion OUDB may present with similar phenotypic insomnia symptoms as patients with ID or CID but report more sleep-disturbing somatic symptoms and EDS. These data have important implications for tailoring behavioral and pharmacological treatments of insomnia to this specific patient population. Support Junior Faculty Development Program, Penn State College of Medicine

scholarly journals 0476 Readiness and Stages of Change in a Behavioral Sleep Medicine Clinical Sample: From Pre-Contemplation to Struggling to Maintain Change

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A182-A183
Author(s):  
G Amatrudo ◽  
K Puzino ◽  
E Bourchtein ◽  
S L Calhoun ◽  
J Fernandez-Mendoza
Keyword(s):  
Rhode Island ◽  
Stages Of Change ◽  
Transtheoretical Model ◽  
Behavioral Treatment ◽  
Readiness To Change ◽  
Clinical Sample ◽  
Significant Proportion ◽  
Sleep Medicine ◽  
Treatment Center ◽  
Penn State

Abstract Introduction Stages of change in the transtheoretical model are used to assess a patient’s readiness to change, which may help providers tailor behavioral treatment (BT). As research has focused on substance abuse, there is a significant lack of data in individuals presenting for behavioral sleep medicine (BSM) treatment. Methods 146 consecutive patients (46.1±16.0 years, 61.6% female, 19.9% minority) who were evaluated at the BSM program of Penn State Hershey Sleep Research & Treatment Center completed the University of Rhode Island Change Assessment Scale (URICA) assessing readiness to change (RtC) and pre-contemplation (P), contemplation (C), preparation/action (A) and struggling to maintain (M) stages of change. Subjects also completed the Insomnia Treatment Acceptability Scale (ITAS) and Dysfunctional Beliefs and Attitudes about Sleep Scale (DBAS). Results The average RtC score was 9.4, with 21.9% of the sample in stage P, 56.2% in C and 21.9% in A. The average P (53.2±7.6), C (49.1±10.1), A (48.8±12.3) and M (37.7±9.1) scores suggested an overall “contemplation cluster profile”. Higher RtC (r=0.37), C (r=0.31) and A (r=0.24) scores were associated with greater acceptability of BT, while higher P scores were associated with lower acceptability of BT (r=-0.22). In contrast, higher M scores were associated with greater acceptability of pharmacological treatment (r=0.21) as well as higher DBAS scores, including sleep medication expectations (r=0.23). Conclusion Patients attending a BSM program typically present at a contemplation stage, which indicates intention to start changing sleep behaviors within the next few months with some ambivalence in regards to pros/cons of such change. A significant proportion of patients struggle to maintain change and present with higher acceptability for pharmacological interventions, which may hinder the effectiveness of BT and may require specific therapeutic approaches. Support Department of Psychiatry, Penn State College of Medicine

scholarly journals Evaluation of the Reliability and Validity of the Persian Version of Urticaria Control Test (UCT)

2021 ◽  
Author(s):  
Maryam Khoshkhui ◽  
Karsten Weller ◽  
Javad Fadaee ◽  
Marcus Maurer ◽  
Farahzad Jabbari Azad ◽  
...  
Keyword(s):  
Internal Consistency ◽  
Chronic Urticaria ◽  
Convergent Validity ◽  
Reliability And Validity ◽  
Internal Consistency Reliability ◽  
Patient Reported Outcome ◽  
Life Questionnaire ◽  
Control Test ◽  
Persian Version ◽  
Patient Reported

The urticaria control test (UCT) is a patient-reported outcome measure (PROM) for chronic urticaria (CU) patients. As a Persian version of the UCT was not available, the present research aimed to develop such a version, to test its reliability and validity as well as to evaluate urticaria control among Persian-speaking patients. This research was conducted at the Urticaria Centre of Reference and Excellence (UCARE) of Ghaem Hospital, Mashhad, Iran. In a first step, a linguistically validated Persian version of the UCT was developed through a structured forward and backward translation process and subsequent cognitive debriefing interviews. In a second step, the Persian version of the UCT was completed by 100 well-characterized CU patients together with two anchor instruments, the Chronic Urticaria Quality of life Questionnaire (CU-Q2oL) and the urticaria activity score (UAS), to obtain information on its internal consistency reliability and convergent validity. The Persian version of the UCT was found to have acceptable internal consistency reliability with a Cronbach's alpha coefficient of 0.68. In addition, the results obtained with the Persian UCT correlated with the CU-Q2oL total score (-0.48, p<0.001) and the UAS (-0.404, p˂0.001), suggesting convergent validity. Virtually all patients had poorly controlled CU (UCT<12). A Persian version of the UCT is now available and may help to improve the assessment and monitoring of disease control in Persian-speaking CU patients and to optimize treatment decisions.

The Portuguese Version of the Depressive Experiences Questionnaire (DEQ): Results from a Validation Program in Clinical and non Clinical Samples

2013 ◽  
Vol 16 ◽  
Author(s):  
Rui C. Campos ◽  
Avi Besser ◽  
Sidney J. Blatt
Keyword(s):  
Convergent Validity ◽  
Clinical Sample ◽  
Depression Scale ◽  
Reliability And Validity ◽  
Brief Symptom Inventory ◽  
Self Report ◽  
Clinical Samples ◽  
Reliability Factor ◽  
Validity Data ◽  
Portuguese Version

AbstractThe Depressive Experiences Questionnaire (DEQ, Blatt, D’Afflitti, & Quinlan, 1976, 1979), a self-report measure used in personality research, assesses the constructs of Dependency and Self-Criticism as vulnerability factors in depression (Blatt, 1974, 1990, 2004) and psychopathology more generally (Blatt, 2008; Blatt & Shichman, 1983). This study establishes a Portuguese version of the DEQ with six samples: a bilingual sample to test the measurement equivalence of the Portuguese DEQ, and two college student samples, two community samples and a clinical sample, to test the reliability, factor structure and criterion, convergent and predictive validity of this translation of the DEQ. A measure of depression (Center for Epidemiologic Studies Depression Scale; CES-D; Radloff, 1977) and of general psychopathology (Brief Symptom Inventory; BSI; Derogatis, 1993) evaluated the convergent validity of the DEQ. Findings indicate satisfactory reliability and validity of the Portuguese DEQ, and the value of the DEQ for investigating the relationship between personality and depression and between personality and psychopathology more generally. It is important to note, however, that these conclusions are based on a limited clinical sample. Additional reliability and validity data are needed with a larger clinical sample.

The Hypersomnia Severity Index: reliability, construct and criterion validity in a clinical sample with sleep disorders

2021 ◽  
Author(s):  
Julio Fernandez-Mendoza ◽  
Kristina Puzino ◽  
Gregory Amatrudo ◽  
Elizaveta Bourchtein ◽  
Susan L. Calhoun ◽  
...  
Keyword(s):  
Sleep Disorders ◽  
Clinical Sample ◽  
Severity Index ◽  
Criterion Validity

The Picture Anxiety Test (PAT)

2012 ◽  
Vol 71 (2) ◽  
pp. 73-81 ◽  
Author(s):  
Kathrin Dubi ◽  
Kristen L. Lavallee ◽  
Silvia Schneider
Keyword(s):  
Externalizing Behavior ◽  
Convergent Validity ◽  
Community Sample ◽  
Reliability And Validity ◽  
Clinical Samples ◽  
Composite Scale ◽  
Anxiety Test ◽  
Test Retest Reliability ◽  
Very High ◽  
Sex And Age Differences

This study extends prior research on the Picture Anxiety Test (PAT; Dubi & Schneider, 2009 ) in clinical samples, by examining psychometric properties and acceptance in a community sample of 153 4–8-year-old children. Children completed the PAT and the RCMAS, a well-established questionnaire measuring anxiety. Parents and teachers completed questionnaires on anxiety and externalizing behavior. In addition, a panel of psychologists and psychiatrists evaluated the PAT for quality and utility. Results indicated high internal consistencies for the subscales and composite scale, very high interrater reliability, and moderate to high test-retest reliability. Substantial correlations between the PAT and the RCMAS indicated good convergent validity. Sex and age differences were found for some subscales. Agreement between children and their parents and teachers was generally low. Children reported high acceptance of the PAT, and the panel of psychologists and psychiatrists rated the PAT as high in both quality and utility. Results were consistent with prior research on the PAT in clinical samples and indicate reliability and validity for assessing anxiety in a subclinical community sample.

Reliability and Validity of the German Version of the Young Schema Questionnaire – Short Form 3 (YSQ-S3)

2013 ◽  
Vol 29 (3) ◽  
pp. 205-212 ◽  
Author(s):  
Levente Kriston ◽  
Janina Schäfer ◽  
Gitta A. Jacob ◽  
Martin Härter ◽  
Lars P. Hölzel
Keyword(s):  
Convergent Validity ◽  
Short Form ◽  
Community Sample ◽  
Reliability And Validity ◽  
Dimensional Structure ◽  
Clinical Samples ◽  
Care Utilization ◽  
German Version ◽  
Young Schema Questionnaire ◽  
Schema Questionnaire

To date, the psychometric properties of the German version of the Young Schema Questionnaire – Short Form 3 (YSQ-S3) have not yet been examined. We investigated the reliability and validity of the German version of the YSQ-S3. In a community sample of 1,150 participants and a clinical sample of 30 psychiatric inpatients, we performed reliability analysis, confirmatory factor analysis, and correlation analyses, and tested for group differences using analysis of variance. The YSQ-S3 proved to be reliable and corresponded to the theoretically proposed 18-dimensional structure. Schema scores were positively associated with measures of psychopathology and personality disorder, indicating convergent validity. Furthermore, the YSQ-S3 differentiated between participant subgroups defined by level of health-care utilization, supporting discriminant validity. We conclude that the YSQ-S3 is a psychometrically sound instrument that can be used in German-speaking countries in research on early maladaptive schemas. Further research is necessary particularly in larger clinical samples.

scholarly journals Validation of the PTSD Checklist for DSM-5 (PCL-5) on Patients Injured in Car Accidents

2021 ◽  
Vol 3 (2) ◽  
pp. 154-159
Author(s):  
Zack Z. Cernovsky ◽  
Milad Fattahi ◽  
Larry C. Litman ◽  
David M. Diamond
Keyword(s):  
Convergent Validity ◽  
Motor Vehicle ◽  
Brief Pain Inventory ◽  
Severity Index ◽  
Criterion Validity ◽  
Control Group ◽  
Vehicle Accidents ◽  
Dsm 5 ◽  
Ptsd Checklist ◽  
Neuropsychological Symptoms

Background: The PTSD Checklist for DSM-5 (PCL-5), is presently the most widely used psychological measure of PTSD along the criteria of DSM-5. We examined the criterion validity of PCL-5 separately for each of its 20 items by comparing scores of patients injured in high impact motor vehicle accidents (MVAs) to scores of persons in a control group. In addition, we evaluated criterion and convergent validity of the PCL-5 total scores. Method: De-identified data of 80 post-MVA patients (mean age 38.9 years, SD=12.8) included their scores on the PCL-5, Brief Pain Inventory (BPI), Insomnia Severity Index (ISI), Rivermead Post-concussion Symptoms Questionnaire, Subjective Neuropsychological Symptoms Scale (SNPSS), ratings of depression, anger, and anxiety (Items 10 to 12 of the Whiplash Disability Questionnaire), and three questionnaire measures of driving anxiety (Steiner’s, Whetstone’s, and DAQ). The patients were assessed, on the average, 49.7 weeks (SD=36.3) after their MVA, but all still experienced active post-MVA symptoms requiring therapy. The PCL-5 scores were also available from 21 controls (mean age 43.0 years, SD=20.3). Results and Discussion: With respect to criterion validity of the PCL-5, the post-MVA patients differed significantly from the control group not only with respect to their total PCL-5 scores, but also on all 20 individual items of the PCL-5, and also on all 4 subscales of PCL-5 (Intrusion, Avoidance, Altered Cognitions/Mood, and Arousal). The PCL-5 total scores correlated significantly to all three measures of post-MVA driving anxiety, post-MVA pain and insomnia, post-MVA depression, anger, and generalized anxiety, and to post-MVA subjective neuropsychological symptoms in the post-concussion and whiplash spectrum. Conclusions: Both the criterion and convergent validity of the PCL-5 for the use on post-MVA patients are excellent.

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