When Bonding Fails: Clinical Assessment of High Risk Families. By Frank G. Bolton, Jr. Beverly Hills, Calif.: Sage Publications, 1983. 224 pp. $28.00 cloth, $14.00 paper

Social Work ◽  
1985 ◽  
Vol 30 (6) ◽  
pp. 530-531
Author(s):  
Merilyn M. Salomon
Keyword(s):  
High Risk ◽  
Clinical Assessment ◽  
High Risk Families

Effectiveness of reverse cascade screening for familial hypercholesteroleamia in very high risk families in China

2017 ◽  
Vol 263 ◽  
pp. e235-e236
Author(s):  
Xue Wu ◽  
Jing Pang ◽  
Jie Peng ◽  
Yan Chen ◽  
Jing Hong ◽  
...  
Keyword(s):  
High Risk ◽  
Cascade Screening ◽  
Very High ◽  
High Risk Families

scholarly journals Variants in the Signaling Protein TSAd are Associated with Susceptibility to Ovarian Cancer in BRCA1/2 Negative High Risk Families

2012 ◽  
Vol 7 ◽  
pp. BMI.S10815 ◽  
Author(s):  
Ludmila Kaplun ◽  
Aviva Levine Fridman ◽  
Wei Chen ◽  
Nancy K. Levin ◽  
Sidra Ahsan ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
High Risk ◽  
Cancer Risk ◽  
Allelic Variation ◽  
High Risk Population ◽  
Ovarian Cancer Risk ◽  
Familial Ovarian Cancer ◽  
Cell Growth And Differentiation ◽  
Brca1 Brca2 ◽  
High Risk Families

A substantial fraction of familial ovarian cancer cases cannot be attributed to specific genetic factors. The discovery of additional susceptibility genes will permit a more accurate assessment of hereditary cancer risk and allow for monitoring of predisposed women in order to intervene at the earliest possible stage. We focused on a population with elevated familial breast and ovarian cancer risk. In this study, we identified a SNP rs926103 whose minor allele is associated with predisposition to ovarian but not breast cancer in a Caucasian high-risk population without BRCA1/ BRCA2 mutations. We have found that the allelic variation of rs926103, which alters amino acid 52 of the encoded protein SH2D2A/TSAd, results in differences in the activity of this protein involved in multiple signal transduction pathways, including regulation of immune response, tumor vascularization, cell growth, and differentiation. Our observation provides a novel candidate genetic biomarker of elevated ovarian cancer risk in members of high-risk families without BRCA1/2 mutations, as well as a potential therapeutic target, TSAd.

Mutation detection rates associated with specific selection criteria for BRCA1/2 testing in 1854 high-risk families: A monocentric Italian study

2016 ◽  
Vol 32 ◽  
pp. 65-71 ◽  
Author(s):  
Jacopo Azzollini ◽  
Giulietta Scuvera ◽  
Eleonora Bruno ◽  
Patrizia Pasanisi ◽  
Daniela Zaffaroni ◽  
...  
Keyword(s):  
High Risk ◽  
Selection Criteria ◽  
Mutation Detection ◽  
Detection Rates ◽  
Italian Study ◽  
High Risk Families

Principles of nutritional support

2018 ◽  
pp. 199-206
Author(s):  
Abdullah Jibawi ◽  
Mohamed Baguneid ◽  
Arnab Bhowmick
Keyword(s):  
Risk Factor ◽  
High Risk ◽  
Parenteral Nutrition ◽  
Clinical Assessment ◽  
Nutritional Support ◽  
Length Of Hospital Stay ◽  
Screening Methods ◽  
Hospital Patients ◽  
Lower Infection ◽  
Malnutrition Universal Screening Tool

Malnutrition is a commonly found risk factor in hospitalized patients. All hospital patients, especially the high-risk ones, should be offered nutritional screening. Methods of screening include MUST (Malnutrition Universal Screening Tool) and the patient should have a thorough clinical assessment and investigations. The patient should meet adequate calorie requirement either by oral or enteral or parenteral nutrition. Malnourished patients receiving nutrition supplements demonstrated lower infection rates and shorter length of hospital stay compared to no supplements.

Clinical assessment for high-risk patients with non-alcoholic fatty liver disease in primary care and diabetology practices

2020 ◽  
Vol 52 (3) ◽  
pp. 513-526 ◽  
Author(s):  
Zobair M. Younossi ◽  
Kathleen E. Corey ◽  
Naim Alkhouri ◽  
Mazen Noureddin ◽  
Ira Jacobson ◽  
...  
Keyword(s):  
Primary Care ◽  
Liver Disease ◽  
High Risk ◽  
Fatty Liver ◽  
Clinical Assessment ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
High Risk Patients ◽  
Risk Patients ◽  
Alcoholic Fatty Liver Disease
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