scholarly journals Relative contribution of membrane‐bound complement regulatory proteins CD55, CD59, CD46, and soluble factor H to resistance of human B lymphoma cells to complement

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Viviana P Ferreira ◽  
Michael K. Pangburn
Keyword(s):  
Factor H ◽  
Regulatory Proteins ◽  
Soluble Factor ◽  
Lymphoma Cells ◽  
Complement Regulatory Proteins ◽  
B Lymphoma ◽  
Relative Contribution ◽  
B Lymphoma Cells ◽  
Membrane Bound

The role of bcl-xL in CD40-mediated rescue from anti-μ-induced apoptosis in WEHI-231 B lymphoma cells

1995 ◽  
Vol 25 (5) ◽  
pp. 1352-1357 ◽  
Author(s):  
Michael S. K. Choi ◽  
Lawrence H. Boise ◽  
Alexander R. Gottschalk ◽  
José Quintans ◽  
Craig B. Thompson ◽  
...  
Keyword(s):  
Lymphoma Cells ◽  
B Lymphoma ◽  
B Lymphoma Cells ◽  
Wehi 231 ◽  
Induced Apoptosis

The expression of membrane-bound complement regulatory proteins CD46, CD55 and CD59 in oral lichen planus

2021 ◽  
Vol 124 ◽  
pp. 105064
Author(s):  
Lulu Li ◽  
Beibei Cong ◽  
Xixi Yu ◽  
Songsong Deng ◽  
Mengjia Liu ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Regulatory Proteins ◽  
Complement Regulatory Proteins ◽  
Membrane Bound ◽  
Oral Lichen

Efficacy of anti-CD20 chimeric Fab’ fragment on proliferation of B lymphoma cells

2001 ◽  
Vol 46 (14) ◽  
pp. 1182-1186 ◽  
Author(s):  
Zengzu Lai ◽  
Dongsheng Xiong ◽  
Dongmei Fan ◽  
Yuanfu Xu ◽  
Hanzhi Liu ◽  
...  
Keyword(s):  
Fab Fragment ◽  
Lymphoma Cells ◽  
B Lymphoma ◽  
B Lymphoma Cells ◽  
Anti Cd20

CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo

2004 ◽  
Vol 53 (12) ◽  
pp. 1135-1145 ◽  
Author(s):  
Katrin U. Lundin ◽  
Valentina Screpanti ◽  
Hilde Omholt ◽  
Peter O. Hofgaard ◽  
Hideo Yagita ◽  
...  
Keyword(s):  
T Cells ◽  
Cd4 T Cells ◽  
Lymphoma Cells ◽  
B Lymphoma ◽  
B Lymphoma Cells

scholarly journals Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome

Blood ◽  
2006 ◽  
Vol 108 (4) ◽  
pp. 1267-1279 ◽  
Author(s):  
Jessica Caprioli ◽  
Marina Noris ◽  
Simona Brioschi ◽  
Gaia Pianetti ◽  
Federica Castelletti ◽  
...  
Keyword(s):  
Disease Recurrence ◽  
Factor H ◽  
Response To Therapy ◽  
Regulatory Proteins ◽  
Response To Treatment ◽  
Complement Factor ◽  
Genetic Studies ◽  
Complement Regulatory Proteins ◽  
Uremic Syndrome ◽  
The Impact

Abstract Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy with manifestations of hemolytic anemia, thrombocytopenia, and renal impairment. Genetic studies have shown that mutations in complement regulatory proteins predispose to non–Shiga toxin–associated HUS (non-Stx–HUS). We undertook genetic analysis on membrane cofactor protein (MCP), complement factor H (CFH), and factor I (IF) in 156 patients with non-Stx–HUS. Fourteen, 11, and 5 new mutational events were found in MCP, CFH, and IF, respectively. Mutation frequencies were 12.8%, 30.1%, and 4.5% for MCP, CFH, and IF, respectively. MCP mutations resulted in either reduced protein expression or impaired C3b binding capability. MCP-mutated patients had a better prognosis than CFH-mutated and nonmutated patients. In MCP-mutated patients, plasma treatment did not impact the outcome significantly: remission was achieved in around 90% of both plasma-treated and plasma-untreated acute episodes. Kidney transplantation outcome was favorable in patients with MCP mutations, whereas the outcome was poor in patients with CFH and IF mutations due to disease recurrence. This study documents that the presentation, the response to therapy, and the outcome of the disease are influenced by the genotype. Hopefully this will translate into improved management and therapy of patients and will provide the way to design tailored treatments.

scholarly journals Rituximab (anti-CD20)-modified AZD-2014-encapsulated nanoparticles killing of B lymphoma cells

2018 ◽  
Vol 46 (sup2) ◽  
pp. 1063-1073 ◽  
Author(s):  
Xiaolong Tang ◽  
Chunmei Xie ◽  
Zhenyou Jiang ◽  
Amin Li ◽  
Shiyu Cai ◽  
...  
Keyword(s):  
Lymphoma Cells ◽  
B Lymphoma ◽  
B Lymphoma Cells ◽  
Anti Cd20 ◽  
Encapsulated Nanoparticles
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