scholarly journals Role of the T‐type calcium channel in the spontaneous phasic contraction of pregnant rat uterine smooth muscle

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Si‐eun Lee ◽  
Duck‐sun Ahn ◽  
Bok‐soon Kang ◽  
Young‐ho Lee
Keyword(s):  
Smooth Muscle ◽  
Calcium Channel ◽  
Pregnant Rat ◽  
Phasic Contraction ◽  
Uterine Smooth Muscle

The Role of Mitogen-Activated Protein Kinase in Oxytocin-Induced Contraction of Uterine Smooth Muscle in Pregnant Rat

1996 ◽  
Vol 229 (3) ◽  
pp. 938-944 ◽  
Author(s):  
Ataru Nohara ◽  
Masahide Ohmichi ◽  
Koji Koike ◽  
Nobuyuki Masumoto ◽  
Mamoru Kobayashi ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Protein Kinase ◽  
Mitogen Activated Protein Kinase ◽  
Pregnant Rat ◽  
Uterine Smooth Muscle ◽  
Mitogen Activated Protein

Malignant uterine smooth muscle tumors: Role of etoposide, cisplatin, and doxorubicin (EPA) chemotherapy

1996 ◽  
Vol 63 (3) ◽  
pp. 145-147 ◽  
Author(s):  
E. Resnik ◽  
S. K. Chambers ◽  
M. L. Carcangiu ◽  
E. I. Kohorn ◽  
P. E. Schwartz ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Tumors

The role of hypoxia related angiogenesis in uterine smooth muscle tumors

2014 ◽  
Vol 90 (2) ◽  
pp. 102-110 ◽  
Author(s):  
Et Uluer ◽  
S Inan ◽  
K Ozbilgin ◽  
F Karaca ◽  
N Dicle ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Tumors

Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle

Life Sciences ◽  
2018 ◽  
Vol 198 ◽  
pp. 46-55 ◽  
Author(s):  
Leyla Sahin ◽  
Ozge Selin Cevik ◽  
Dilan Deniz Koyuncu ◽  
Kansu Buyukafsar
Keyword(s):  
Smooth Muscle ◽  
Rho Kinase ◽  
Phasic Contraction ◽  
Frog Stomach

Forskolin inhibition of K+ current in pregnant rat uterine smooth muscle cells

1993 ◽  
Vol 240 (2-3) ◽  
pp. 169-176 ◽  
Author(s):  
Yoshihito Inoue ◽  
Keiichi Shimamura ◽  
Nicholas Sperelakis
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Pregnant Rat ◽  
Uterine Smooth Muscle ◽  
K Current

Oxytocin actions on voltage-dependent ionic channels in pregnant rat uterine smooth muscle cells

1992 ◽  
Vol 70 (12) ◽  
pp. 1597-1603 ◽  
Author(s):  
Yoshihito Inoue ◽  
Keiichi Shimamura ◽  
Nicholas Sperelakis
Keyword(s):  
Smooth Muscle ◽  
Voltage Clamp ◽  
Calcium Current ◽  
Uterine Contraction ◽  
Cell Voltage ◽  
Ionic Channels ◽  
Pregnant Rat ◽  
Uterine Smooth Muscle ◽  
Voltage Dependent ◽  
Sodium And Potassium

The effects of oxytocin, a uterotonic polypeptide hormone, on the voltage-dependent slow calcium, fast sodium, and potassium channel currents were studied using whole-cell voltage clamp of freshly isolated cells from late pregnant (18–21 day) rat myometrium. The calcium current was rapidly inhibited by oxytocin (about 25% inhibition at 20 nM) in a dose-dependent manner, and this inhibitory effect was completely reversible by washout. However, inhibition was not observed when barium was used as the charge carrier. Sodium current and potassium current were not modified by oxytocin, thus sodium and potassium currents may not play important roles in oxytocin-induced augmentation of uterine contraction. It is concluded that oxytocin stimulates uterine contraction by mechanisms other than augmentation of the voltage-dependent calcium current, e.g., by release of Ca from sarcoplasmic reticulum (by inositol trisphosphate) or by activation of a receptor-operated Ca channel. The inhibition of the slow calcium current may be induced by the elevation of [Ca]i.Key words: oxytocin, ionic channels, uterine smooth muscle, whole-cell voltage clamp, pregnant rat myometrium.

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