Impaired Arteriolar Dilation in a Mouse Model of Familial Hypercholesterolemia: Impact of Chronic Exercise and Anti‐Cholesterol Therapy

Phoebe A. Stapleton; Adam G. Goodwill; Michael R. Morrisette; Milinda E. James; Jefferson C. Frisbee

doi:10.1096/fasebj.24.1_supplement.593.5

Impaired Arteriolar Dilation in a Mouse Model of Familial Hypercholesterolemia: Impact of Chronic Exercise and Anti‐Cholesterol Therapy

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.593.5 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Phoebe A. Stapleton ◽

Adam G. Goodwill ◽

Michael R. Morrisette ◽

Milinda E. James ◽

Jefferson C. Frisbee

Keyword(s):

Mouse Model ◽

Familial Hypercholesterolemia ◽

Chronic Exercise ◽

Cholesterol Therapy

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Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia

Journal of Genetic Syndromes & Gene Therapy ◽

10.4172/2157-7412.1000106 ◽

2011 ◽

Vol 2 (2) ◽

Cited By ~ 11

Author(s):

Rongying Li ◽

Hsu Chao

Keyword(s):

Gene Therapy ◽

Mouse Model ◽

Familial Hypercholesterolemia ◽

Ldl Cholesterol ◽

Hdl Cholesterol

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Very Low Density Lipoprotein Receptor Gene Therapy in a Mouse Model of Familial Hypercholesterolemia

Drugs Affecting Lipid Metabolism - Medical Science Symposia Series ◽

10.1007/978-94-009-0311-1_30 ◽

1996 ◽

pp. 249-253

Author(s):

Lawrence Chan ◽

Kunihisa Kobayashi

Keyword(s):

Gene Therapy ◽

Mouse Model ◽

Familial Hypercholesterolemia ◽

Receptor Gene ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Very Low Density Lipoprotein ◽

Low Density ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells

Molecular Metabolism ◽

10.1016/j.molmet.2019.09.002 ◽

2019 ◽

Vol 30 ◽

pp. 1-15 ◽

Cited By ~ 7

Author(s):

Daiane F. Engel ◽

Anna N. Grzyb ◽

Jade de Oliveira ◽

Alexandra Pötzsch ◽

Tara L. Walker ◽

...

Keyword(s):

Mouse Model ◽

Familial Hypercholesterolemia ◽

Cholesterol Metabolism ◽

Ldl Receptor ◽

Precursor Cells ◽

Hippocampal Neurogenesis ◽

Adult Hippocampal Neurogenesis ◽

Neural Precursor Cells ◽

Neural Precursor

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Long-Term Stable Expression of Human Apolipoprotein A-I Mediated by Helper-Dependent Adenovirus Gene Transfer Inhibits Atherosclerosis Progression and Remodels Atherosclerotic Plaques in a Mouse Model of Familial Hypercholesterolemia

Circulation ◽

10.1161/01.cir.0000066913.69844.b2 ◽

2003 ◽

Vol 107 (21) ◽

pp. 2726-2732 ◽

Cited By ~ 92

Author(s):

L. Maria Belalcazar ◽

Aksam Merched ◽

Boyd Carr ◽

Kazuhiro Oka ◽

Kuang-Hua Chen ◽

...

Keyword(s):

Gene Transfer ◽

Mouse Model ◽

Familial Hypercholesterolemia ◽

Stable Expression ◽

Atherosclerotic Plaques ◽

Human Apolipoprotein ◽

Atherosclerosis Progression ◽

Apolipoprotein A

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631. In-Vivo LDL Receptor Gene Therapy Is Highly Effective in Reversing Hypercholesterolemia in a Mouse Model of Familial Hypercholesterolemia

Molecular Therapy ◽

10.1016/s1525-0016(16)41073-7 ◽

2003 ◽

Vol 7 (5) ◽

pp. S246 ◽

Cited By ~ 1

Keyword(s):

Gene Therapy ◽

Mouse Model ◽

Familial Hypercholesterolemia ◽

Receptor Gene ◽

Ldl Receptor ◽

Highly Effective

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Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia

Human Gene Therapy Clinical Development ◽

10.1089/humc.2017.007 ◽

2017 ◽

Vol 28 (1) ◽

pp. 28-38 ◽

Cited By ~ 13

Author(s):

Jenny A. Greig ◽

Maria P. Limberis ◽

Peter Bell ◽

Shu-Jen Chen ◽

Roberto Calcedo ◽

...

Keyword(s):

Mouse Model ◽

Familial Hypercholesterolemia ◽

Homozygous Familial Hypercholesterolemia ◽

Toxicology Study

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Biodistribution of AAV8 Vectors Expressing Human Low-Density Lipoprotein Receptor in a Mouse Model of Homozygous Familial Hypercholesterolemia

Human Gene Therapy Clinical Development ◽

10.1089/humc.2013.082 ◽

2013 ◽

Vol 24 (4) ◽

pp. 154-160 ◽

Cited By ~ 22

Author(s):

Shu-Jen Chen ◽

Julio Sanmiguel ◽

Martin Lock ◽

Deirdre McMenamin ◽

Christine Draper ◽

...

Keyword(s):

Mouse Model ◽

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Homozygous Familial Hypercholesterolemia ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia

PLoS ONE ◽

10.1371/journal.pone.0186426 ◽

2017 ◽

Vol 12 (10) ◽

pp. e0186426 ◽

Cited By ~ 24

Author(s):

Filippo Romanelli ◽

AnthonyMarco Corbo ◽

Maryam Salehi ◽

Manisha C. Yadav ◽

Soha Salman ◽

...

Keyword(s):

Coronary Artery Disease ◽

Alkaline Phosphatase ◽

Endothelial Cells ◽

Coronary Artery ◽

Mouse Model ◽

Familial Hypercholesterolemia ◽

Tissue Nonspecific Alkaline Phosphatase ◽

Artery Disease

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377. Metabolic Xenograft Mouse Model for Human Familial Hypercholesterolemia

Molecular Therapy ◽

10.1016/s1525-0016(16)35390-4 ◽

2014 ◽

Vol 22 ◽

pp. S144

Keyword(s):

Mouse Model ◽

Familial Hypercholesterolemia ◽

Xenograft Mouse Model

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Selective Interleukin-12 Synthesis Defect in 12/15-Lipoxygenase-deficient Macrophages Associated with Reduced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia

Journal of Biological Chemistry ◽

10.1074/jbc.m205738200 ◽

2002 ◽

Vol 277 (38) ◽

pp. 35350-35356 ◽

Cited By ~ 86

Author(s):

Lei Zhao ◽

Carolyn A. Cuff ◽

Erin Moss ◽

Ulrike Wille ◽

Tillmann Cyrus ◽

...

Keyword(s):

Mouse Model ◽

Familial Hypercholesterolemia ◽

Interleukin 12

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