scholarly journals Weight loss alone does not fully resolve non‐alcoholic steatohepatitis markers in western diet fed Ldlr ‐/‐ mice: a pilot study (1116.5)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Kelli Lytle ◽  
Donald Jump
Keyword(s):  
Weight Loss ◽  
Pilot Study ◽  
Western Diet ◽  
Alcoholic Steatohepatitis

scholarly journals Non-alcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet

2021 ◽  
Author(s):  
Souradipta Ganguly ◽  
German Aleman Muench ◽  
Linshan Shang ◽  
Sara Brin Rosenthal ◽  
Gibraan Rahman ◽  
...  
Keyword(s):  
Western Diet ◽  
Alcoholic Steatohepatitis

scholarly journals Western diet, obesity and bariatric surgery sequentially modulated anxiety, eating patterns and brain responses to sucrose in adult Yucatan minipigs

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yentl Gautier ◽  
Damien Bergeat ◽  
Yann Serrand ◽  
Noémie Réthoré ◽  
Mathilde Mahérault ◽  
...  
Keyword(s):  
Weight Loss ◽  
Eating Behavior ◽  
Dorsal Striatum ◽  
Western Diet ◽  
Affective States ◽  
Cognitive Components ◽  
Positron Emission ◽  
Brain Responses ◽  
Oral Sucrose ◽  
Weight Loss Interventions

AbstractPalatable sweet/fatty foods overconsumption is a major risk factor for obesity and eating disorders, also having an impact on neuro-behavioural hedonic and cognitive components comparable to what is described for substance abuse. We hypothesized that Yucatan minipigs would show hedonic, cognitive, and affective neuro-behavioral shifts when subjected to western diet (WD) exposure without weight gain, after the onset of obesity, and finally after weight loss induced by caloric restriction with (RYGB) or without (Sham) gastric bypass. Eating behavior, cognitive and affective abilities were assessed with a spatial discrimination task (holeboard test) and two-choice feed tests. Brain responses to oral sucrose were mapped using 18F-FDG positron emission tomography. WD exposure impaired working memory and led to an “addiction-type” neuronal pattern involving hippocampal and cortical brain areas. Obesity induced anxiety-like behavior, loss of motivation, and snacking-type eating behavior. Weight loss interventions normalized the motivational and affective states but not eating behavior patterns. Brain glucose metabolism increased in gustatory (insula) and executive control (aPFC) areas after weight loss, but RYGB showed higher responses in inhibition-related areas (dorsal striatum). These results showed that diet quality, weight loss, and the type of weight loss intervention differently impacted brain responses to sucrose in the Yucatan minipig model.

Preferred versus Nonpreferred Treatment, and Self-Control Training versus Determination Raising as Treatments of Obesity: A Pilot Study

1976 ◽  
Vol 38 (1) ◽  
pp. 191-198 ◽  
Author(s):  
D. C. Murray
Keyword(s):  
Weight Loss ◽  
Pilot Study ◽  
Treatment Group ◽  
Self Control ◽  
The Other ◽  
Significant Weight Loss ◽  
Overweight Women

Of 12 overweight women half received 10 wk. of self-control training and the rest received an equal period aimed at increasing determination to lose weight. Half of each treatment group had expressed a preference for the type of treatment they received and half for the other type of treatment. Both groups lost a statistically significant amount of weight, and at a 3-mo. follow-up there was still a significant weight loss. Follow-up at 6 mo. on 9 of the 12 original subjects indicated both groups regained much of their lost weight. There was no evidence that either type of treatment or receiving one's preferred type of treatment was related to weight loss.

Assessment of Cardiorespiratory and Metabolic Responses in Women with Obesity After Surgically Induced Weight Loss: Results from a Pilot Study

2021 ◽  
Author(s):  
Tatiana Onofre ◽  
Nicole Oliver ◽  
Renata Carlos ◽  
Davi Fialho ◽  
Renata C. Corte ◽  
...  
Keyword(s):  
Weight Loss ◽  
Pilot Study ◽  
Metabolic Responses ◽  
Surgically Induced

Provider and patient intervention to improve weight loss: A pilot study in a public hospital clinic

2008 ◽  
Vol 72 (1) ◽  
pp. 56-62 ◽  
Author(s):  
Terry C. Davis ◽  
Michael S. Wolf ◽  
Pat F. Bass ◽  
Connie L. Arnold ◽  
Jian Huang ◽  
...  
Keyword(s):  
Weight Loss ◽  
Pilot Study ◽  
Public Hospital ◽  
Hospital Clinic

scholarly journals A pilot study of acceptance-based behavioural weight loss for adolescents with obesity

2019 ◽  
Vol 47 (6) ◽  
pp. 686-696 ◽  
Author(s):  
Jena Shaw Tronieri ◽  
Thomas A. Wadden ◽  
Sharon M. Leonard ◽  
Robert I. Berkowitz
Keyword(s):  
Physical Activity ◽  
Weight Loss ◽  
Pilot Study ◽  
Lifestyle Modification ◽  
Psychological Treatment ◽  
Psychosocial Outcomes ◽  
Cognitive Restraint ◽  
Acceptance And Commitment ◽  
Medium Increase

AbstractBackground:Acceptance and commitment therapy (ACT) is a psychological treatment that has been found to increase weight loss in adults when combined with lifestyle modification, compared with the latter treatment alone. However, an ACT-based treatment for weight loss has never been tested in adolescents.Methods:The present pilot study assessed the feasibility and acceptability of a 16-week, group ACT-based lifestyle modification treatment for adolescents and their parents/guardians. The co-primary outcomes were: (1) mean acceptability scores from up to 8 biweekly ratings; and (2) the percentage reduction in body mass index (BMI) from baseline to week 16. The effect size for changes in cardiometabolic and psychosocial outcomes from baseline to week 16 also was examined.Results:Seven families enrolled and six completed treatment (14.3% attrition). The mean acceptability score was 8.8 for adolescents and 9.0 for parents (on a 1–10 scale), indicating high acceptability. The six adolescents who completed treatment experienced a 1.3% reduction in BMI (SD = 2.3, d = 0.54). They reported a medium increase in cognitive restraint, a small reduction in hunger, and a small increase in physical activity. They experienced small improvements in most quality of life domains and a large reduction in depression.Conclusions:These preliminary findings indicate that ACT plus lifestyle modification was a highly acceptable treatment that improved weight, cognitive restraint, hunger, physical activity, and psychosocial outcomes in adolescents with obesity.

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