The Clinical Implications of Cognitive Impairment in Elderly Patients with Chronic Heart Failure

2001 ◽  
Vol 16 (1) ◽  
pp. 47-55 ◽  
Author(s):  
Inger Ekman ◽  
Björn Fagerberg ◽  
Ingmar Skoog
Keyword(s):  
Heart Failure ◽  
Cognitive Impairment ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Clinical Implications

scholarly journals Correlation Analysis of Cognitive Impairment And Malnutrition In Elderly Patients With Chronic Heart Failure

2021 ◽  
Author(s):  
Hong Liang ◽  
Xiaoping Li ◽  
Wei Lv ◽  
Kexin Zhang ◽  
Jiyan Leng
Keyword(s):  
Heart Failure ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Odds Ratio ◽  
Nutritional Assessment ◽  
Mini Nutritional Assessment ◽  
Fat Free Mass ◽  
Arm Circumference

Abstract Aims: The purpose of this study was to evaluate the correlation between cognitive impairment (CI) and malnutrition in elderly patients with chronic heart failure (CHF) and to determine the relationship between different nutritional indexes and cognitive impairment in patients with chronic heart failure.Methods and results: We examined the correlation between CI and nutritional indicators in elderly hospitalized patients with CHF. The nutritional status of patients was evaluated by Mini Nutritional Assessment（MNA), anthropometric assessment indicators, human component analysis indicators and laboratory tests indicators. Use of the Min-mental state examinatsion (MMSE) to evaluate cognitive function. The study included 184 heart failure patients aged 60 or older. According to the international common cognitive function assessment scale, the patients were divided into CI group and not CI group. In terms of nutrition, compared with those without CI, patients with CI had lower MNA score, Body mass index (BMI), arm circumference, calf circumference, fat free mass, upper arm muscle circumference, lymphocytes absolute value, hemoglobin, hematocrit, albumin, prealbumin, and cholesterol (P < 0.001). Among them, albumin (odds ratio [OR]=0.767, P < 0.05), arm circumference (odds ratio [OR]=0.614; P < 0.05), MNA score (odds ratio [OR]=0.675; P < 0.001) was significantly correlated with CI in elderly patients with CHF, and We found that the AUC was the largest when the three indexes were combined to draw the ROC curve (AUC: 0.935).Conclusions: Our findings emphasize that malnutrition is common in the elderly population, and that it is strongly associated with cognitive decline. Identifying and treating malnutrition is essential for all older people.

Elderly patients with chronic heart failure have higher risk of geriatric syndromes: results of the nursing study

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
I Tsareva ◽  
N Vorobyeva ◽  
G Semochkina ◽  
Y Kotovskaya ◽  
O Tkacheva
Keyword(s):  
Heart Failure ◽  
Regression Analysis ◽  
Cognitive Impairment ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Barthel Index ◽  
Clinical Manifestations ◽  
Geriatric Syndromes ◽  
Depression Risk ◽  
Norton Scale

Abstract Background The prevalence of chronic heart failure (CHF) and geriatric syndromes increases with age, however the associations between these conditions have not yet been studied. Purpose To evaluate the associations between CHF and geriatric syndromes in elderly patients. Methods Four hundred and seventy-two in-patients (18% male) aged 75–100 (mean 81±4) years were included in the nursing study. Patients were examined by nurses with a specially designed nursing assessment algorithm that included Mini-Cog test, Morse Fall scale, Norton scale, Barthel Activities of daily living Index, Short Physical Performance Battery (SPPB) tests, Mini Nutritional Assessment (MNA) scale, Geriatric Depression Scale (GDS-15), and a number of other questionnaires. Results CHF was observed in 180 patients (38%). Functional class (FC) of II (NYHA) was diagnosed in 133 (74%) of them, FC of III – in 47 (26%). Patients with and without CHF did not differ by age and gender. CHF patients had lower points on Norton scale (17,6±2,0 vs 18,2±1,8; p&lt;0,001), Barthel Index (92,0±13,9 vs 95,0±9,1; p=0,009), SPPB (5,3±3,2 vs 6,0±3,3; p=0,018), and higher points on Morse Fall scale (44,3±19,9 vs 39,3±21,1; p=0,007) and GDS-15 (4,7±3,2 vs 4,2±3,3; p=0,041) compared to non-CHF patients. CHF patients had higher frequency of frailty (75% vs 65%; p=0,029), depression (47% vs 38%; p=0,041), and cognitive impairment (54% vs 41%; p=0,008). Univariate regression analysis showed that CHF presence increased the frailty risk by 1,6 times (OR 1,59; 95% CI 1,05–2,40; p=0,029), the depression risk – by 1,5 times (OR 1,48; 95% CI 1,02–2,16; p=0,041), and the cognitive impairment risk – by 1,7 times (OR 1,65; 95% CI 1,14–2,40; p=0,009). Among CHF patients, severity of CHF clinical manifestations correlated with severity of geriatric syndromes. CHF patients with FC of II had higher points of Norton scale (17,8±1,9 vs 16,9±2,1; p=0,005), Barthel Index (93,4±12,9 vs 88,3±15,8; p=0,005), SPPB (4,4±3,3 vs 3,9±3,0; p=0,001), walk speed (0,58±0,26 vs 0,45±0,22 m/s; p=0,002), and lower points of GDS-15 (4,4±3,3 vs 5,5±2,9; p=0,008) compared to CHF patients with FC of III. The frequency of depression was higher in CHF patients with FC of III (64% vs 41%; p=0,008). Univariate regression analysis showed that in CHF patients with FC of III the depression risk was higher by 2,5 times (OR 2,50; 95% CI 1,26–4,98; p=0,009) compared to CHF patients with FC of II. Conclusion Elderly CHF patients had higher risk of geriatric syndromes such as frailty, depression, and cognitive impairment. Among CHF patients, severity of CHF clinical manifestations correlated with severity of geriatric syndromes. Funding Acknowledgement Type of funding source: None

scholarly journals Cognitive Impairment Among Elderly Patients With Chronic Heart Failure and Related Factors

2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Zohreh Taraghi ◽  
Ahmad-Ali Akbari Kamrani ◽  
Mahshid Foroughan ◽  
Jamshid Yazdani ◽  
Ali Mahdavi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cognitive Impairment ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Related Factors

scholarly journals Features of Pathogenesis and Course of Type 2 Diabetes Mellitus and Comorbid with it Cardiovascular Pathology in Elderly Patients

2021 ◽  
Vol 6 (3) ◽  
pp. 22-36
Author(s):  
Yu. G. Gorb ◽  
◽  
V. I. Strona ◽  
O. V. Tkachenko ◽  
S. A. Serik ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Impairment ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Microvascular Complications ◽  
The Body

The features of the pathogenesis and course of type 2 diabetes mellitus and diseases of the cardiovascular system comorbid with it are considered in patients of elderly and old age – coronary artery disease, arterial hypertension, chronic heart failure. The leading role of insulin resistance, hyperglycemia and dyslipidemia in the development of metabolic, homeostatic disorders, the formation of oxidative stress and endothelial dysfunction, which, together with age-related changes in the body, contribute to the progression of type 2 diabetes mellitus and microvascular complications, primarily diabetic cardiomyopathy. Particular attention is paid to the relationship between cognitive impairment, type 2 diabetes mellitus and chronic heart failure. The main factors that worsen the course and prognosis of type 2 diabetes mellitus in elderly patients, in particular, hypertension, atrial fibrillation, diabetic polyneuropathy, nephropathy, and other concomitant diseases, have been identified. Lack of compensation for type 2 diabetes due to metabolic disorders leads to the development of diabetic cardiovascular autonomic neuropathy, diabetic cardiomyopathy along with the progression of atherosclerotic lesions of different localization. The course of type 2 diabetes in these patients is often complicated by geriatric syndrome, which contains a set of cognitive impairment, senile weakness, depression, functional disorders, polymorbidity. Cognitive disorders negatively affect the course of type 2 diabetes and its complications, significantly disrupting the process of teaching patients the methods of self-control, following the advice of a doctor. It is noted that the management of this category of patients should be individual and include adequate correction of hyperglycemia to prevent microvascular complications and hypoglycemic conditions, as well as reduce cardiovascular mortality and maintain quality of life. Rational selection of drugs, taking into account the factors that determine their impact on the body of elderly patients with type 2 diabetes mellitus and possible adverse drug reactions, will increase the effectiveness and safety of drug therapy in such patients. Optimizing therapeutic approaches for elderly patients with type 2 diabetes requires effective changes in the health care system to provide them with comprehensive medical and social care according to their special needs

The cardiopulmonary exercise test is safe and reliable in elderly patients with chronic heart failure

2007 ◽  
Vol 8 (8) ◽  
pp. 608-612 ◽  
Author(s):  
Angela Beatrice Scardovi ◽  
Claudio Coletta ◽  
Renata De Maria ◽  
Silvia Perna ◽  
Nadia Aspromonte ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Exercise Test ◽  
Cardiopulmonary Exercise Test ◽  
Cardiopulmonary Exercise

scholarly journals Chronic Heart Failure: Clinical Implications of Iron Homeostasis Disturbances Revisited

Cureus ◽  
2022 ◽  
Author(s):  
Leonardo P Suciadi ◽  
Joshua Henrina ◽  
Iwan Cahyo Santosa Putra ◽  
Irvan Cahyadi ◽  
Hoo Felicia Hadi Gunawan
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Iron Homeostasis ◽  
Clinical Implications

scholarly journals Chronic heart failure as multimorbid state

2019 ◽  
Vol 26 (4) ◽  
pp. 90-101 ◽  
Author(s):  
L. G. Voronkov ◽  
A.V. Liashenko ◽  
N. A. Tkach ◽  
L. P. Paraschenyuk
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Cognitive Impairment ◽  
Chronic Heart Failure ◽  
Iron Deficiency ◽  
Arterial Hypertension ◽  
Renal Dysfunction ◽  
Life Quality ◽  
High Class ◽  
High Level

Regulatory, structural and functional disturbances of other organs and systems (kidney, hepar, vessels, skeletal muscles, brain etc) play the substantial role in CHF. These disturbances may be the conseguences of pre-existing states (hypertension, diabetes, hypo- or hyperthyreoidism etc) and from, other side, may reflect the progressive inherent changes in chronic heart failure (CHF) per se. In particular, currently relevant comorbidities in this syndrome are insulin resistance, diabetes mellitus, renal dysfunction, cognitive impairment, depression peripheral myopathy. Every of them demonstrate the close pathophysiologic interplay with CHF which results in clinical prognosis impairment and in decrease of life quality. Prevalence of renal dysfunction described in 39 % of patients with CHF in our research. Renal dysfunction connected with older age, high class of NYHA, diabetes mellitus, arterial hypertension, higher level of citrulline and uric acid in patients with CHF. Patients with iron deficiency characterized with high class of NYHA, low functionality and poor quality of life. In patients with iron deficiency noted high level of mortality and many critical clinical events. Prevalence of cognitive impairment described in 85 % of patients with CHF in our research. Cognitive dysfunction associated with older age, high class of NYHA, diabetes mellitus, arterial hypertension, bad life quality, high level of ceruloplasmin in patients with CHF. Taking to account above-mentioned comorbidities in quideline-recommended management of CHF and the use of additional therapeutic approaches targeted to its treatment represent the contemporary strategy of personalized treatment in this syndrome.

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