scholarly journals Correlation Analysis of Cognitive Impairment And Malnutrition In Elderly Patients With Chronic Heart Failure

Author(s):  
Hong Liang ◽  
Xiaoping Li ◽  
Wei Lv ◽  
Kexin Zhang ◽  
Jiyan Leng

Abstract Aims: The purpose of this study was to evaluate the correlation between cognitive impairment (CI) and malnutrition in elderly patients with chronic heart failure (CHF) and to determine the relationship between different nutritional indexes and cognitive impairment in patients with chronic heart failure.Methods and results: We examined the correlation between CI and nutritional indicators in elderly hospitalized patients with CHF. The nutritional status of patients was evaluated by Mini Nutritional Assessment(MNA), anthropometric assessment indicators, human component analysis indicators and laboratory tests indicators. Use of the Min-mental state examinatsion (MMSE) to evaluate cognitive function. The study included 184 heart failure patients aged 60 or older. According to the international common cognitive function assessment scale, the patients were divided into CI group and not CI group. In terms of nutrition, compared with those without CI, patients with CI had lower MNA score, Body mass index (BMI), arm circumference, calf circumference, fat free mass, upper arm muscle circumference, lymphocytes absolute value, hemoglobin, hematocrit, albumin, prealbumin, and cholesterol (P < 0.001). Among them, albumin (odds ratio [OR]=0.767, P < 0.05), arm circumference (odds ratio [OR]=0.614; P < 0.05), MNA score (odds ratio [OR]=0.675; P < 0.001) was significantly correlated with CI in elderly patients with CHF, and We found that the AUC was the largest when the three indexes were combined to draw the ROC curve (AUC: 0.935).Conclusions: Our findings emphasize that malnutrition is common in the elderly population, and that it is strongly associated with cognitive decline. Identifying and treating malnutrition is essential for all older people.

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
I Tsareva ◽  
N Vorobyeva ◽  
G Semochkina ◽  
Y Kotovskaya ◽  
O Tkacheva

Abstract Background The prevalence of chronic heart failure (CHF) and geriatric syndromes increases with age, however the associations between these conditions have not yet been studied. Purpose To evaluate the associations between CHF and geriatric syndromes in elderly patients. Methods Four hundred and seventy-two in-patients (18% male) aged 75–100 (mean 81±4) years were included in the nursing study. Patients were examined by nurses with a specially designed nursing assessment algorithm that included Mini-Cog test, Morse Fall scale, Norton scale, Barthel Activities of daily living Index, Short Physical Performance Battery (SPPB) tests, Mini Nutritional Assessment (MNA) scale, Geriatric Depression Scale (GDS-15), and a number of other questionnaires. Results CHF was observed in 180 patients (38%). Functional class (FC) of II (NYHA) was diagnosed in 133 (74%) of them, FC of III – in 47 (26%). Patients with and without CHF did not differ by age and gender. CHF patients had lower points on Norton scale (17,6±2,0 vs 18,2±1,8; p&lt;0,001), Barthel Index (92,0±13,9 vs 95,0±9,1; p=0,009), SPPB (5,3±3,2 vs 6,0±3,3; p=0,018), and higher points on Morse Fall scale (44,3±19,9 vs 39,3±21,1; p=0,007) and GDS-15 (4,7±3,2 vs 4,2±3,3; p=0,041) compared to non-CHF patients. CHF patients had higher frequency of frailty (75% vs 65%; p=0,029), depression (47% vs 38%; p=0,041), and cognitive impairment (54% vs 41%; p=0,008). Univariate regression analysis showed that CHF presence increased the frailty risk by 1,6 times (OR 1,59; 95% CI 1,05–2,40; p=0,029), the depression risk – by 1,5 times (OR 1,48; 95% CI 1,02–2,16; p=0,041), and the cognitive impairment risk – by 1,7 times (OR 1,65; 95% CI 1,14–2,40; p=0,009). Among CHF patients, severity of CHF clinical manifestations correlated with severity of geriatric syndromes. CHF patients with FC of II had higher points of Norton scale (17,8±1,9 vs 16,9±2,1; p=0,005), Barthel Index (93,4±12,9 vs 88,3±15,8; p=0,005), SPPB (4,4±3,3 vs 3,9±3,0; p=0,001), walk speed (0,58±0,26 vs 0,45±0,22 m/s; p=0,002), and lower points of GDS-15 (4,4±3,3 vs 5,5±2,9; p=0,008) compared to CHF patients with FC of III. The frequency of depression was higher in CHF patients with FC of III (64% vs 41%; p=0,008). Univariate regression analysis showed that in CHF patients with FC of III the depression risk was higher by 2,5 times (OR 2,50; 95% CI 1,26–4,98; p=0,009) compared to CHF patients with FC of II. Conclusion Elderly CHF patients had higher risk of geriatric syndromes such as frailty, depression, and cognitive impairment. Among CHF patients, severity of CHF clinical manifestations correlated with severity of geriatric syndromes. Funding Acknowledgement Type of funding source: None


Author(s):  
Eun Young Kim ◽  
Youn-Jung Son

Cognitive impairment is more prevalent in heart failure (HF) patients. Anemia can influence cognitive ability and is likely more prevalent in elderly patients with HF. However, there are limited data on the association of anemia with cognitive impairment in elderly HF patients. This study aimed to identify the association between anemia and cognitive impairment in elderly HF patients. This secondary data analysis included 181 patients aged 60 years or older with HF. Patients were categorized into an anemic or non-anemic group based on World Health Organization (WHO) criteria. We assessed the cognitive function using the Modified Mini-Mental State (3MS) at the time of enrollment. The prevalence of anemia and cognitive impairment in older patients with HF was the same at 35.4%. The main finding of the multiple logistic regression indicated that compared to a non-anemic status, anemia increased the risk of cognitive impairment (odds ratio (OR) = 4.268, 95% confidence interval (CI) = 1.898–9.593, p < 0.001). Healthcare providers should recognize the value of the significance of early assessment of anemic status and cognitive function following HF. A prospective cohort study should identify the pathway of the association between anemia and incidence of cognitive impairment.


2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Zohreh Taraghi ◽  
Ahmad-Ali Akbari Kamrani ◽  
Mahshid Foroughan ◽  
Jamshid Yazdani ◽  
Ali Mahdavi ◽  
...  

2021 ◽  
Vol 6 (3) ◽  
pp. 22-36
Author(s):  
Yu. G. Gorb ◽  
◽  
V. I. Strona ◽  
O. V. Tkachenko ◽  
S. A. Serik ◽  
...  

The features of the pathogenesis and course of type 2 diabetes mellitus and diseases of the cardiovascular system comorbid with it are considered in patients of elderly and old age – coronary artery disease, arterial hypertension, chronic heart failure. The leading role of insulin resistance, hyperglycemia and dyslipidemia in the development of metabolic, homeostatic disorders, the formation of oxidative stress and endothelial dysfunction, which, together with age-related changes in the body, contribute to the progression of type 2 diabetes mellitus and microvascular complications, primarily diabetic cardiomyopathy. Particular attention is paid to the relationship between cognitive impairment, type 2 diabetes mellitus and chronic heart failure. The main factors that worsen the course and prognosis of type 2 diabetes mellitus in elderly patients, in particular, hypertension, atrial fibrillation, diabetic polyneuropathy, nephropathy, and other concomitant diseases, have been identified. Lack of compensation for type 2 diabetes due to metabolic disorders leads to the development of diabetic cardiovascular autonomic neuropathy, diabetic cardiomyopathy along with the progression of atherosclerotic lesions of different localization. The course of type 2 diabetes in these patients is often complicated by geriatric syndrome, which contains a set of cognitive impairment, senile weakness, depression, functional disorders, polymorbidity. Cognitive disorders negatively affect the course of type 2 diabetes and its complications, significantly disrupting the process of teaching patients the methods of self-control, following the advice of a doctor. It is noted that the management of this category of patients should be individual and include adequate correction of hyperglycemia to prevent microvascular complications and hypoglycemic conditions, as well as reduce cardiovascular mortality and maintain quality of life. Rational selection of drugs, taking into account the factors that determine their impact on the body of elderly patients with type 2 diabetes mellitus and possible adverse drug reactions, will increase the effectiveness and safety of drug therapy in such patients. Optimizing therapeutic approaches for elderly patients with type 2 diabetes requires effective changes in the health care system to provide them with comprehensive medical and social care according to their special needs


2020 ◽  
Vol 22 ◽  
pp. 01023
Author(s):  
Artem Popov ◽  
Nadezhda Izmozherova ◽  
Tatiana Oboskalova ◽  
Yelena Gavrilova ◽  
Yelena Safianik

Objective: to assess frequency and clinical significance of cognitive function impairment in postmenopausal woman. Methods: A cross-sectional study included 462 women under the age of 65. Arterial hypertension, carbohydrate metabolism impairment, chronic heart failure, coronary heart disease frequency were registered. Mini Mental State Examination was used to assess cognitive function. Results: mild cognitive function impairment was found in 223 (48%) postmenopausal women, 28 cases (6%) of dementia were registered. Mild cognitive impairment was associated with arterial hypertension (OR 1.74; 95% CI 1.16 – 2.64), chronic heart failure (OR 1.70; 1.16 – 2.49), dementia was associated with coronary heart disease (3.49; 1.54>7.89). Conclusion: cognitive impairment is frequent in postmenopausal women and associated with arterial hypertension, chromic heart failure and coronary heart disease.


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