Effect of Type of Early Infant Feeding on Fatty Acid Composition of Plasma Lipid Classes in Full-Term Infants During the Second 6 Months of Life

Background: Term infants can be categorized into 3 sub-groups: early term (37w0d to 38w6d), full term (39w0d to 40w6d), and late term (41w0d and beyond). However, the fatty acid composition among the 3 groups of term infants has not been investigated. The association between fatty acid composition and gestational period of term infants in Japan is unclear. Methods: We assessed the fatty acid composition of maternal erythrocyte membranes in the third trimester and of cord erythrocyte membranes at birth in 212 healthy term Japanese infants using data from a prospective hospital-based cohort study. Results: In maternal erythrocyte membranes, docosahexaenoic acid (DHA) levels and omega-3 index were significantly higher in the late-term group than in the early-term group. In cord erythrocyte membranes, DHA levels were not significantly different between the 3 groups; late-term infants showed significantly higher DHA/arachidonic acid (ARA) and lower 20: 3n-6 and ARA levels compared to early-term infants. Gestational period positively correlated with the DHA status in maternal and cord erythrocyte membranes. Conclusions: Fatty acid composition in maternal and cord erythrocyte membranes varies between early-, full-, and late-term infants, and the greater gestational period may contribute to the relatively high n-3 polyunsaturated fatty acids status in term infants. Furthermore, maternal DHA status in the third semester directly correlates with gestational period in pregnant Japanese women.

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Fatty Acid Profile of Plasma Lipid Classes in Coronary Heart Disease, in Primary Hyperlipoproteinemias, and in Healthy Subjects

Canadian Journal of Biochemistry ◽

10.1139/o73-200 ◽

1973 ◽

Vol 51 (11) ◽

pp. 1509-1514 ◽

Cited By ~ 11

Author(s):

Claude Allard ◽

Jean Davignon ◽

Yves L. Marcel ◽

Claude Goulet ◽

Kanta Kuba ◽

...

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Acid Composition ◽

Healthy Subjects ◽

Total Phospholipid ◽

Plasma Lipid ◽

Coronary Arteriography ◽

Lipid Classes ◽

Gas Liquid Chromatography ◽

Coronary Patients

The plasma fatty acid composition of the cholesteryl esters triglycerides, and total phospholipid was studied by gas–liquid chromatography in clinically healthy subjects and coronary patients; all of whom had had a recent selective coronary arteriography. The fatty acid composition of the same lipid classes mentioned above was investigated in the different types of hyperlipoproteinemia. All the subjects or patients investigated were on a regular diet. The fatty acid patterns in the various lipid classes were found the same in coronary patients and in healthy subjects. However, great differences were noted in the fatty acid profiles in the various types of hyperlipoproteinemia. Noteworthy was the fact that type II (especially type IIa) contained the greatest proportion of linoleic acid in all lipid classes. This study indicated again biochemical heterogeneity within types of primary hyperlipoproteinemias and also between types IIa and IIb.

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