ACUTE PROTEIN SUPPLEMENTATION DOES NOT ALTER POWER OUTPUT, PLASMA AMMONIA CONCENTRATION AND ACID-BASE BALANCE DURING HIGH INTENSITY INTERMITTENT EXERCISE 1097

1997 ◽  
Vol 29 (Supplement) ◽  
pp. 192
Author(s):  
J. A. Potteiger ◽  
B. A. Dolezal ◽  
K. S. Almuzaini ◽  
M. D. Haub
Keyword(s):  
Power Output ◽  
High Intensity ◽  
Intermittent Exercise ◽  
Ammonia Concentration ◽  
Protein Supplementation ◽  
Acid Base Balance ◽  
Acid Base ◽  
Plasma Ammonia ◽  
Base Balance

Does low serum carnosinase activity favor high-intensity exercise capacity?

2014 ◽  
Vol 116 (5) ◽  
pp. 553-559 ◽  
Author(s):  
Audrey Baguet ◽  
Inge Everaert ◽  
Benito Yard ◽  
Verena Peters ◽  
Johannes Zschocke ◽  
...  
Keyword(s):  
High Intensity ◽  
Genetic Selection ◽  
High Intensity Exercise ◽  
Acid Base Balance ◽  
Acid Base ◽  
Long Distance ◽  
Double Blind ◽  
Maximal Power Output ◽  
Cross Sectional ◽  
Base Balance

Given the ergogenic properties of β-alanyl-L-histidine (carnosine) in skeletal muscle, it can be hypothesized that elevated levels of circulating carnosine could equally be advantageous for high-intensity exercises. Serum carnosinase (CN1), the enzyme hydrolyzing the dipeptide, is highly active in the human circulation. Consequently, dietary intake of carnosine usually results in rapid degradation upon absorption, yet this is less pronounced in subjects with low CN1 activity. Therefore, acute carnosine supplementation before high-intensity exercise could be ergogenic in these subjects. In a cross-sectional study, we determined plasma CN1 activity and content in 235 subjects, including 154 untrained controls and 45 explosive and 36 middle- to long-distance elite athletes. In a subsequent double-blind, placebo-controlled, crossover study, 12 men performed a cycling capacity test at 110% maximal power output (CCT 110%) following acute carnosine (20 mg/kg body wt) or placebo supplementation. Blood samples were collected to measure CN1 content, carnosine, and acid-base balance. Both male and female explosive athletes had significantly lower CN1 activity (14% and 21% lower, respectively) and content (30% and 33% lower, respectively) than controls. Acute carnosine supplementation resulted only in three subjects in carnosinemia. The CCT 110% performance was not improved after carnosine supplementation, even when accounting for low/high CN1 content. No differences were found in acid-base balance, except for elevated resting bicarbonate following carnosine supplementation and in low CN1 subjects. In conclusion, explosive athletes have lower serum CN1 activity and content compared with untrained controls, possibly resulting from genetic selection. Acute carnosine supplementation does not improve high-intensity performance.

scholarly journals Effect of Ginger Powder (Zingiber officinale) on Acid-Base Balance, Rumen and Blood Constituents in Healthy Egyptian Sheep

2021 ◽  
Vol 10 (1) ◽  
pp. 55-58
Keyword(s):  
Volatile Fatty Acids ◽  
Rumen Fluid ◽  
Zingiber Officinale ◽  
Ammonia Concentration ◽  
Acid Base Balance ◽  
Acid Base ◽  
Blood Constituents ◽  
Rumen Acidosis ◽  
Base Balance ◽  
Ginger Powder

Medicinal herbs have been used for several thousand years in traditional medicine and are known to be inexpensive, effective, readily available, and safe to use, with almost no side effects. As no previous research focused on the effect of ginger powder (Zingiber officinale) on acid-base balance in sheep, the goal of this study was studying the effects of ginger (Zingiber officinale) powder on acid-base balance, rumen, and blood constituents. Ten Egyptian ewes were given ginger powder 500mg/kg bwt orally in the morning before feeding for 5 days. Blood and rumen juice samples were collected in the morning on 0 (control), 3rd, and 5th day before feeding. Results generally showed a significant increase in rumen fluid pH, WBCS, lymphocytes, MCH, and MCHC. Significant decrease in total volatile fatty acids, serum total protein, and globulin were recorded. Ginger maintained acid-base balance, rumen protozoa activity, total protozoa count, rumen ammonia concentration, RBCs, PCV, Hemoglobin, neutrophils, albumin, BUN, Creatinine, GGT, and AST within normal range. Depending on changes in blood and rumen constituents we may suggest a recommendation for using ginger supplementation as 500mg/kg bwt orally for 3-5days as an immune stimulant and in the treatment of rumen acidosis and respiratory affections in sheep.

scholarly journals The acid-base status of prenatal pups of the dogfish, Squalus acanthias, in the uterine environment

1986 ◽  
Vol 125 (1) ◽  
pp. 173-179 ◽  
Author(s):  
G. A. Kormanik ◽  
D. H. Evans
Keyword(s):  
Plasma Lipid ◽  
Ammonia Concentration ◽  
Squalus Acanthias ◽  
Acid Base Balance ◽  
Acid Base ◽  
Co2 Partial Pressure ◽  
Uterine Fluid ◽  
Base Balance ◽  
Acid Base Status ◽  
Uterine Environment

The acid-base status of late-term Squalus acanthias L. pups in the uterine seawater environment was examined. Blood values for pH, total CO2, partial pressure of CO2, urea and sodium concentrations in late-term pups were not significantly different from those of the mothers. Haematocrit was slightly lower, while total plasma lipid and ammonia concentrations were several times higher. The uterine environment in which these pups reside and maintain normal acid-base status is nevertheless quite remarkable. In the later months of gestation, up to six pups (approx. 60 g each) reside in each horn of the uterus, in about 100 ml of seawater, in which they ventilate. While the major ion concentrations of the uterine fluid resemble normal seawater, the pH may be as low as 5.9, and the ammonia concentration as high as 22 mmol l-1. This system provides a unique opportunity to study acid-base balance, respiration and nitrogenous waste excretion in developing elasmobranchs under quite unusual conditions.

scholarly journals Ingestion of Sodium Bicarbonate (NaHCO3) Following a Fatiguing Bout of Exercise Accelerates Postexercise Acid-Base Balance Recovery and Improves Subsequent High-Intensity Cycling Time to Exhaustion

2017 ◽  
Vol 27 (5) ◽  
pp. 429-438 ◽  
Author(s):  
Lewis A. Gough ◽  
Steven Rimmer ◽  
Callum J. Osler ◽  
Matthew F. Higgins
Keyword(s):  
Sodium Bicarbonate ◽  
Body Mass ◽  
High Intensity ◽  
Recovery Period ◽  
Time To Exhaustion ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
Experimental Trials ◽  
Cycling Time

This study evaluated the ingestion of sodium bicarbonate (NaHCO3) on postexercise acid-base balance recovery kinetics and subsequent high-intensity cycling time to exhaustion. In a counterbalanced, crossover design, nine healthy and active males (age: 23 ± 2 years, height: 179 ± 5 cm, body mass: 74 ± 9 kg, peak mean minute power (Wpeak) 256 ± 45 W, peak oxygen uptake (V̇O2peak) 46 ± 8 ml.kg-1.min-1) performed a graded incremental exercise test, two familiarization and two experimental trials. Experimental trials consisted of cycling to volitional exhaustion (TLIM1) at 100% WPEAK on two occasions (TLIM1 and TLIM2) interspersed by a 90 min passive recovery period. Using a double-blind approach, 30 min into a 90 min recovery period participants ingested either 0.3 g.kg-1 body mass sodium bicarbonate (NaHCO3) or a placebo (PLA) containing 0.1 g.kg-1 body mass sodium chloride (NaCl) mixed with 4 ml.kg-1 tap water and 1 ml.kg-1 orange squash. The mean differences between TLIM2 and TLIM1 was larger for PLA compared with NaHCO3 (-53 ± 53 vs. -20 ± 48 s; p = .008, d = 0.7, CI =-0.3, 1.6), indicating superior subsequent exercise time to exhaustion following NaHCO3. Blood lactate [Bla-] was similar between treatments post TLIM1, but greater for NaHCO3 post TLIM2 and 5 min post TLIM2. Ingestion of NaHCO3 induced marked increases (p < .01) in both blood pH (+0.07 ± 0.02, d = 2.6, CI = 1.2, 3.7) and bicarbonate ion concentration [HCO3-] (+6.8 ± 1.6 mmo.l-1, d = 3.4, CI = 1.8, 4.7) compared with the PLA treatment, before TLIM2. It is likely both the acceleration of recovery, and the marked increases of acid-base after TLIM1 contributed to greater TLIM2 performance compared with the PLA condition.

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